CAS: 17616-04-5; 4-(1H-Imidazol-1-yl)Benzoic Acid
该化合物是一种有机化合物,其特征为一丁二烯酸和苯并二氮酸功能组,该化合物一般是白色至非白固体,由于存在碳化物酸组,在水和酒精等极地溶剂中溶解.Iniidazole环有助于其潜在的生物活动,使其对药物研究感兴趣,特别是针对各种生物途径的药物开发.由于碳酸细胞,该化合物具有复合酸性,可参与氢的结合,影响其与其他分子的抗反应和互动.此外,其结构还允许与金属离子进行潜在协调,这在化学和催化方面可能具有相关性.
相似化合物
10040-98-9 86718-08-3 25372-03-6物理性质
MSDS等安全信息
- GHS象形图
- GHS符号GHS07;
注释: Exclamation mark - 危险类别特定目标器官毒性 - 单次接触 类别3
皮肤腐蚀/刺激 类别2
严重眼刺激 类别2
急性毒性 类别4(吸入)
急性毒性 类别4(经口)
严重眼刺激 类别2A - 警示词Warning(警告)
- 危险描述H335 |可能引起呼吸道刺激.
H315 |造成皮肤刺激.
H319 |造成严重眼刺激.
H332 |吸入有害.
H302 |吞咽有害. - 防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
- 危险品标志Xi
- 风险等级Irritant
- 安全声明26-36-37/39-36/37/39-22
- 危险类别码36/37/38
- WGK Germany3
欧盟法规
ECHA物质C&L通报上下游产品
CAS号288-32-4 咪唑 | CAS号586-76-5 对溴苯甲酸 | CAS号74-11-3 对氯苯甲酸 | CAS号104-88-1 对氯苯甲醛 | CAS号86718-07-2 4-(1-咪唑基)苯甲酸乙酯 | CAS号125234-35-7 4-imidazol-1-yl...合成工艺路线路线简述
- 合成目标产物 4-(1H-Imidazol-1-yl)Benzoic Acid 主要起始原料 Imidazole And 4-Iodobenzoic Acid
- (文献来源)合成步骤主要原料 Imidazole 和 4-Iodobenzoic Acid
📜1-(4-甲醛基苯基)咪唑置于1-羟基环己基苯基甲酮,Sodium Hydroxide体系中,用 乙二醇二甲醚 用作溶剂,以91%的收率获得4-(1H-咪唑-1-基)苯甲酸
参考文献:通过氢原子转移将伯醇和醛氧化成羧酸
标题:通过氢原子转移将伯醇和醛氧化成羧酸
摘要:伯醇和伯醛氧化成相应的羧酸是有机合成中的基本反应.在本文中,我们报告了一种用于氧化伯醇和醛的新化学选择性工艺.这种无金属反应具有新的氧化剂,易于操作的程序,高分离产率以及即使在易受攻击的仲醇和叔丁烷亚磺酰胺存在下也具有非常好至优异的官能团耐受性的特点.
Doi:10.1021/acs.Orglett.1C02188
海关参考信息
- 2905110000-甲醇
2906210000-苄醇
2912110000-甲醛
2912210000-苯甲醛 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-9574189-B2
优先权日:2005-12-01
标题:Enzymatic encoding methods for efficient synthesis of large libraries
发明人：FRANCH THOMAS; LUNDORF MIKKEL DYBRO; JACOBSEN SØREN NYBOE; OLSEN EVA KAMPMANN; ANDERSEN ANNE LEE; HOLTMANN ANETTE; HANSEN ANDERS HOLM; SØRENSEN ANDERS MALLING; GOLDBECH ANNE; DE LEON DAEN; KALDOR DITTE KIEVSMOSE; SLØK FRANK ABILDGAARD; HUSEMOEN GITTE NYSTRUP; DOLBERG JOHANNES; Jensen Kim Birkebæ; PEDERSEN LENE; NØRREGAARD-MADSEN MADS; GODSKESEN MICHAEL ANDERS; GLAD SANNE SCHRØDER; NEVE SØREN; THISTED THOMAS; KRONBORG TINE TITILOLA AKINLEMINU; SAMS CHRISTIAN KLARNER; FELDING JAKOB; FRESKGÃ…RD PER-OLA; GOULIAEV ALEX HAAHR; PEDERSEN HENRIK
权利人:FRANCH THOMAS; LUNDORF MIKKEL DYBRO; JACOBSEN SØREN NYBOE; OLSEN EVA KAMPMANN; ANDERSEN ANNE LEE; HOLTMANN ANETTE; HANSEN ANDERS HOLM; SØRENSEN ANDERS MALLING; GOLDBECH ANNE; DE LEON DAEN; KALDOR DITTE KIEVSMOSE; SLØK FRANK ABILDGAARD; HUSEMOEN GITTE NYSTRUP; DOLBERG JOHANNES; Jensen Kim Birkebæ; PEDERSEN LENE; NØRREGAARD-MADSEN MADS; GODSKESEN MICHAEL ANDERS; GLAD SANNE SCHRØDER; NEVE SØREN; THISTED THOMAS; KRONBORG TINE TITILOLA AKINLEMINU; SAMS CHRISTIAN KLARNER; FELDING JAKOB; FRESKGÃ…RD PER-OLA; GOULIAEV ALEX HAAHR; PEDERSEN HENRIK; NUEVOLUTION AS
摘要:Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).
专利号:US-11702652-B2
优先权日:2005-12-01
标题:Enzymatic encoding methods for efficient synthesis of large libraries
专利号:US-2009264300-A1
优先权日:2005-12-01
标题 :Enzymatic encoding methods for efficient synthesis of large libraries
专利号:US-2020216836-A1
优先权日:2005-12-01
标题 :Enzymatic encoding methods for efficient synthesis of large libraries
专利号:EP-1957644-B1
优先权日:2005-12-01
标 题 :Enzymatic encoding methods for efficient synthesis of large libraries
专利号:US-2019330618-A1
优先权日:2005-12-01
标题 :Enzymatic encoding methods for efficient synthesis of large libraries
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
参考文献:10.1107/s1600536811015522
摘要:Kong F, Yu Z. Aqua[1-(4-carboxyphenyl)-1H-imidazole-κN3](pyridine-2,6-dicarboxylato-κ3O2,N,O6)copper(II) monohydrate. Acta Crystallogr E Struct Rep Online. 2011 May 20;67(6):m783. doi: 10.1107/s1600536811015522.
📝 需求与反馈
尽可能描述清楚需求与问题信息
