CAS: 139-85-5; 3,4-Dihydroxybenzaldehyde

相似化合物

17345-61-8 3897-89-0 3943-89-3

上下游产品

CAS号621-59-0 异香兰素； 3-羟基-4-甲氧... | CAS号121-33-5 香草醛 | CAS号120-57-0 胡椒醛 | CAS号859451-00-6 DL-3,4-dihydrox... | CAS号869277-74-7 isatinsulfonic acid | CAS号869224-41-9 sodium isatin-s... | CAS号775-01-9 DL-3,4-二羟基扁桃酸 | CAS号4383-06-6 3-羟基-4-甲氧基苯甲醇 | CAS号120-80-9 邻苯二酚 | CAS号10586-13-7 3,4-bis(trimeth... | CAS号10554-65-1 6-(2-Nitrovinyl... | CAS号34098-18-5 3-氯-4,5-二羟基苯甲醛 | CAS号54337-90-5 3,4-二羟基苯甲酰胺 | CAS号3897-89-0 3,4-二羟基苄醇 | CAS号3131-52-0 5,6-二羟基吲哚 | CAS号4049-39-2 3-羟基-4-苄氧基苯甲醛 | CAS号50773-56-3 3-(苄氧基)-4-羟基苯甲醛 | CAS号5447-02-9 3,4-二苄氧基苯甲醛 | CAS号3934-87-0 5-羟基香草醛

香草醛置于aluminium(III) Iodide,N,N-二甲基甲酰胺二甲基缩醛体系中,用 乙腈 用作溶剂,化学反应 18.0H,以88%的收率获得3,4-二羟基苯甲醛
参考文献:三碘化铝和n,N-二甲基甲酰胺二甲基乙缩醛对酸不稳定的芳烷基醚的手性辅助选择性裂解.
标题:三碘化铝和n,N-二甲基甲酰胺二甲基乙缩醛对酸不稳定的芳烷基醚的手性辅助选择性裂解.
摘要:N,N-二甲基甲酰胺二甲基乙缩醛(dmf-Dma)利用三碘化铝通过相邻基团的参与选择性裂解醚.包括羧酸盐,烯丙基,叔丁基二甲基甲硅烷基(tbs)和叔丁氧羰基(boc)在内的各种酸不稳定官能团均完好无损.该方法为裂解邻苯二酚单烷基醚和从乙缩醛型保护基(如甲氧基甲基(mom),甲氧基乙氧基甲基(mem)和四氢吡喃基(thp))上化学选择性解吸酚提供了一种有效的方法.
Doi:10.1021/acs.Joc.0C00290

专利信息

专利号:WO-2021014395-A1
优先权日:2019-07-24
标题:Process for the synthesis of deuterated capsaicin, capsaicinoids and synthetic capsaicin analogs
发明人：ORUGANTI SRINIVAS; AMRUTAPU SRAVANTH KUMAR; SAMPATH MAGESH; SEN SAIKAT
权利人:DR REDDY’S INST OF LIFE SCIENCES
摘要:The present application provides novel processes for the synthesis of deuterated intermediates of capsaicinoids, particularly II, III, IV and V of capsaicinoids, relating to pharmaceutical applications. The invention also provides novel intermediates of compounds of formula IX, XIV, XV, XVI, XVII, XVIII, XX and XXI utilized in the process of making deuterated capsaicin II, III, IV and V.

专利号:US-6552213-B1
优先权日:2002-05-10
标 题:Stereoselective route to produce tris-O-substituted-(E)-1-(3,5-dihydroxyphenyl)-2-(4-hydroxyphenyl)ethene, an intermediate in the synthesis of trans-resveratrol
发明人：DESHPANDE PANDURANG BALWANT; SENTHILKUMAR UDAYAMPALAYAM PAL; ANDREW GNANAPRAKASAM
权利人:ORCHID CHEMICALS & PHARM LTD
摘要:The present invention relates to a new stereoselective method for the preparation of tris-O-substituted-(E)-1-(3,5-dihydroxyphenyl)-2-(4-hydroxyphenyl)ethene derivative of the formula (I) which is a key intermediate in the synthesis of trans-resveratrol (I, R2=R2=R3=H). The invention also provides a method for the exclusive synthesis of trans-isomer of compounds of formula (I) without any contamination of cis-isomer.

专利号:US-6251689-B1
优先权日:1998-05-14
标 题:Methods for the solid phase synthesis of combinatorial libraries of benzimidazoles benzoxazoles benzothiazoles and derivatives thereof
发明人：LABORDE EDGARDO; MATSUMOTO YUKIHARU
权利人:TELIK INC
摘要:The present invention provides an efficient and versatile method for the synthesis and screening of combinatorial libraries of benzimidazoles, benzoxazoles, benzothiazoles, and derivatives thereof. In order to expedite the synthesis of large arrays of compounds possessing these core structures, a general methodology for solid phase synthesis of these derivatives is provided. Arrays of benzimidazoles, benzoxazoles, benzothiazoles, and derivatives thereof useful as peptidomimetics and for the identification of agents having antifungal, antiviral, antimicrobial, anticoagulant, and antiulcer activity, or use in the treatment of inflammation, hypertension, cancer, and other conditions can be prepared by this method.

专利号:US-11512303-B2
优先权日:2017-05-27
标 题 :Engineered polypeptides and their applications in the synthesis of beta-hydroxy-alpha-amino acids
发明人：CHEN HAIBIN; BONG YONG KOY; XU QING; ZHOU AMENG; SHEN TIANRAN; YANG JIADONG; YANG ZHUHONG
权利人:ENZYMASTER NINGBO BIO ENG CO LTD
摘要:The present invention provides engineered polypeptides that are useful for the asymmetric synthesis of β-hydroxy-α-amino acids under industrial-relevant conditions. The engineered polypeptides disclosed in this invention were developed through directed evolution based on the ability of catalytic synthesis of (2S, 3R)-2-amino-3-hydroxy-3-(4-nitrophenyl) propanoic acid. The present disclosure also provides polynucleotides encoding engineered polypeptides, host cells capable of expressing engineered polypeptides, and methods of producing β-hydroxy-α-amino acids using engineered polypeptides. Compared to other processes of preparation, the use of the engineered polypeptides of the present invention for the preparation of β-hydroxy-α-amino acids results in high purity of the desired stereoisomers, mild reaction conditions, low pollution and low energy consumption. So, it has good industrial application prospects.

专利号:US-2023119068-A1
优先权日:2020-02-13
标题:Methods for rapid synthesis of pyranoanthocyanins
发明人：ZHU XIAOYI; STRAATHOF NICOLE; MIYAGUSUKU-CRUZADO GONZALO; GIUSTI M MONICA; CANO ISRAEL GARCIA; JIMENEZ-FLORES RAFAEL
权利人:OHIO STATE INNOVATION FOUNDATION
摘要:The present disclosure provides methods for the rapid synthesis of pyranoanthocyanins.

专利号:US-7973175-B2
优先权日:2005-09-28
标 题 :Synthesis of renin inhibitors involving a cycloaddition reaction
发明人：MICKEL STUART J; MARTERER WOLFGANG
权利人:NOVARTIS AG
摘要:The invention related to a novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active compounds, especially renin inhibitors, such as Aliskiren. Inter alia, the invention relates to a process for the manufacture of a compound of the formula III, n nwherein R, R 1 , and R′ are as defined in the specification, or a salt thereof, and a compound of formula IVn n nwherein R, R 1 , R 2 and R′ are as defined in the specification, and processes of manufacturing these.