CAS: 137-05-3; Methyl 2-Cyanoacrylate

上下游产品

氰乙酸甲酯 Methyl Cyanoacetate 105-34-0

📜2-Acetoxy-2-Cyano-Propionic Acid Methyl Ester置于铜体系中,535.0~550.0 °C,26.66 Kpa 条件下,反应生成2-氰基丙烯酸甲酯
参考文献:Derivatives Of Fatty Acids And Method Of Preparing Same
标题:Derivatives Of Fatty Acids And Method Of Preparing Same

专利信息

专利号:US-8563760-B2
优先权日:2009-08-31
标 题:Process for the synthesis of long-chain fatty acids
发明人：FAUQ ABDUL H; EDWARDS ALBERT O
权利人:FAUQ ABDUL H; EDWARDS ALBERT O; MAYO FOUNDATION
摘要:This invention relates to processes for preparing long-chain fatty acids of Formula I: n nand salts thereof, as well as intermediates for the processes, wherein L 1 and L 2 are described herein.

专利号:US-5504252-A
优先权日:1995-05-05
标 题 :Synthesis of cyanoacrylate esters by oxidation of aromatic selenyl cyanopropionates
发明人：KLEMARCZYK PHILIP
权利人:LOCTITE CORP
摘要:A method of preparing an α-cyanoacrylate ester of a desired alcohol includes the steps of n preparing a compound which is an α-selenoaryl-α-cyanopropionate ester of the desired alcohol, n oxidizing said α-selenoaryl-α-cyanopropionate ester to the corresponding selenoxide, n eliminating arylselenic acid from the selenoxide to produce said α-cyanoacrylate ester, and n separating said α-cyanoacrylate ester from the selenic acid. n At temperatures of about 0° C. or higher, the elimination step occurs concurrently with the oxidizing step using a peroxide or ozone oxidizing agent. The desired cyanoacrylate ester is obtained in good yield and very high purity. The method can be used to prepare difficult to synthesize plural functional cyanoacrylate monomers and mono- cyanoacrylate monomers regardless of alcohol chain length.

专利号:US-8288497-B2
优先权日:2008-02-27
标 题 :Synthesis of poly-(P-aryleneethynylene)s in neat water under aerobic conditions
发明人：KANG YOUN K; DERIA PRAVAS; THERIEN MICHAEL J
权利人:KANG YOUN K; DERIA PRAVAS; THERIEN MICHAEL J; UNIV PENNSYLVANIA
摘要:Provided are ethyne synthons comprising boron and related methods. Also provided are related water-soluble arylethynylene polymers capable of being synthesized in neat water under aerobic conditions.

专利号:US-4876323-A
优先权日:1984-02-27
标题:α-substituted acrylic acid esters, their polymers and method of synthesizing same
发明人：ENGEL JAMES F; BYERLEY THOMAS J; CHRISTIE HOWARD W
权利人:MIDWEST RESEARCH INST
摘要:α-Substituted acrylic acid esters, their polymers and adhesives therefrom, and methods of synthesizing these compounds. The compounds of the invention are useful as intermediates in the synthesis of isocyanato esters and can be polymerized to form an effective, non-toxic adhesive. The method of the invention encompasses utilizing the adhesive composition in biomedical applications, such as joining live animal tissue. Other adhesive applications are contemplated for living tissue and inanimate objects. The compounds are also used as monomers which can be polymerized, used in conjunction with other monomers as adhesive compositions, cross-linking agents, dye acceptor additives to vinylic polymers and useful chemical intermediates. The method of the invention encompasses synthesizing the aforementioned monomers and intermediates. Methyl α-(ethoxycarbonamido)acrylate is synthesized from either DL-serine or methyl pyruvate. For use as an intermediate, silyl substitution of the compound is accomplished by reacting the ester with trimethylchlorosilane. This α-substituted silated ester is used as an intermediate in the preparation of methyl α-isocyanatoacrylate, which can be polymerized with N-vinyl-2-pyrrolidone to produce a desirable adhesive. Analagous procedures, starting with L-ethyl serine and L-benzyl serine, respectively, are followed to arrive at the corresponding ethyl and benzyl esters.

专利号:US-2006165683-A1
优先权日:2001-12-05
标题:Methods and compositions for control of bone formation via modulation of sympathetic tone
发明人：KARSENTY GERARD; TAKEDA SHU; ELEFTERIOU FLORENT
权利人:KARSENTY GERARD; TAKEDA SHU; ELEFTERIOU FLORENT
摘要:This invention relates to methods for treatment, diagnosis and prevention of bone disease and comprises methods including measurement and modulation of sympathetic tone and leptin activity. Alteration of sympathetic tone in bone disease can be accomplished by decreasing or increasing leptin synthesis, leptin receptor synthesis, leptin binding to the leptin receptor, and leptin receptor activity. Alteration of sympathetic tone in bone disease can also be accomplished in the foregoing manner, in combination with traditional sympathetic nervous system agonists and/or antagonists, such as, but not limited to, a dopamine β hydroxylase antagonist or a β adrenergic antagonist for treatment or prevention of osteoporosis.

专利号:US-2004127440-A1
优先权日:2000-01-20
标 题:Methods and compositions for control of bone formation via modulation of neuropeptide Y activity
发明人：KARSENTY GERARD; DUCY PATRICIA; AMLING MICHAEL
权利人:BAYLOR COLLEGE MEDICINE
摘要:The invention relates to the method for treatment, diagnosis and prevention of bone disease and comprises methods including inhibiting or increasing neuropeptide Y synthesis, neuropeptide Y receptor synthesis, neuropeptide Y binding to the neuropeptide Y receptor, and neuropeptide Y receptor activity. The invention also relates to screening assays to identify compounds that modulate neuropeptide Y and/or neuropeptide Y receptor activity. The invention further relates to gene therapy methods utilizing neuropeptide Y and neuropeptide Y-related sequences for the treatment and prevention of bone disease.