📜氧化亚镍,水 反应生成氢氧化镍(III)
参考文献:Walker,S. M.;Thornton,E. W.,Water Chem. Nucl. React. Syst. 5: Proc. Int. Conf.,Bournemouth,23-27 oc+
标题:Walker,S. M.;Thornton,E. W.,Water Chem. Nucl. React. Syst. 5: Proc. Int. Conf.,Bournemouth,23-27 oc+
专利信息
专利号:US-2023286918-A1
优先权日:2020-07-02
标 题:Manufacturing process for 3,5-dichloropicolinonitrile for synthesis of vadadustat
发明人:JURKAUSKAS VALDAS; JUNG YOUNG CHUN; KWON TAESOO; KANNAN ARUNACHALAM; GONDI VIJAYA BHASKER
权利人:AKEBIA THERAPEUTICS INC
摘要:Disclosed herein are methods and processes of preparing vadadustat or a pharmaceutically acceptable salts thereof, and intermediates (e.g., a compound of Formula (I), (I-F), (II), or (IV), or a pharmaceutically acceptable salts thereof) useful for the synthesis of vadadustat.
专利号:US-12269802-B2
优先权日:2018-05-09
标题:Process for preparing 2-[[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl] amino] acetic acid
发明人:GORIN BORIS I; LANTHIER CHRISTOPHER M; LUONG ANNE BUU CHAU; COPP JAMES DENSMORE; GONZALEZ JAVIER; JAUTZE SASCHA; KRAUS ERICH; O'CONNOR ALAN
权利人:AKEBIA THERAPEUTICS INC
摘要:Disclosed herein are methods and processes of preparing vadadustat and pharmaceutically acceptable salts thereof, and intermediates of formula (I) and their salts useful for the synthesis of vadadustat.