CAS: 120-15-0; 6-Methoxy-1,2,3,4-Tetrahydroquinoline

该化合物是一个双环有机化合物,其特点是四氢基noline结构,由一个有引信的苯和管道环组成.六点的甲氧基化合物的存在有助于其独特的化学特性,影响其再活性和溶解性.该化合物一般没有色素,可视其纯度和形态而成为黄色液体或固体;由于甲基氧基化合物的替代结构,该化合物呈现中度极性,可增强有机溶剂的溶性. 6-Methoxy-1,2,3,4-ttratrothyquiline 6-Methycycroom, 包括医药化学化学学领域,它可能作为药物开发的支架.其潜在的生物活动,如抗微生物或抗炎效应,是正在进行的研究的主题.此外,它可能参与各种化学反应,包括碱和氧化和氧化,包括碱化剂,它成为有机合成的多种中间体.在处理和储存方面,应参考安全数据.

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合成工艺路线路线简述

    📜6-甲氧基喹啉置于甲醇,Ammonia Borane体系中,化学反应 24.0H,以99%的收率获得6-甲氧基-1,2,3,4-四氢喹啉
    参考文献:双金属 Pdrh-Fe3O4 纳米颗粒催化氨硼烷高选择性喹啉加氢
    标题:双金属 Pdrh-Fe3O4 纳米颗粒催化氨硼烷高选择性喹啉加氢
    摘要:我们报告了在 Fe 3 O 4上使用双金属 Pdrh 合金纳米颗粒在室温下以氨硼烷作为方便的氢源,将喹啉化学选择性氢化为 1,2,3,4-四氢喹啉.在催化剂设计中将钯引入铑使我们能够最大限度地减少喹啉的中毒效应.当我们改变 Pd 与 Rh 的摩尔比时,Pd:Rh 比为 0.23:1.0 的催化剂表现出最高的喹啉还原催化活性,产率 > 99%.此外,使用 Fe 3 O 4作为载体具有独特的优势,因为它可以借助外部磁体轻松地将催化剂从溶液中分离出来,以使催化剂重复使用多达 10 次.
    Doi:10.1016/j.Apcata.2022.118709

    海关参考信息

    专利信息


    专利号:WO-2025065137-A1
    优先权日:2023-09-25
    标 题:Method for producing single-cell protein by means of high-density fermentation
    发明人:WANG BEI; MA GUANG; PAN ZHAOYANG; ZHANG YAPING; MA LINGYAN; ZHANG YONGZHEN
    权利人:WANHUA CHEMICAL GROUP CO LTD
    摘要:Disclosed herein is a method for producing a single-cell protein by means of high-density fermentation. The method comprises: inoculating a Yarrowia lipolytica strain into a seed culture medium for seed culture to obtain a seed liquid; and inoculating the seed liquid into a fermentation culture medium for high-density fermentation, and supplementing same with acetic acid and a nitrogen source during the process of high-density fermentation to obtain the single-cell protein, wherein the carbon source of the seed culture medium comprises a first acetate, and the carbon source of the fermentation culture medium comprises a second acetate and/or a ketone compound. In the present application, the compounding of specific materials and processes effectively increases the growth rate of bacteria and the synthesis rate of single-cell proteins, so that the method can realize the high-density fermentation of bacteria and efficient synthesis of single-cell proteins in a short time, a fermentation product with a higher content of crude proteins can be obtained while the culture time of high-density fermentation is significantly shortened, and the production efficiency and yield of single-cell proteins are greatly improved.

    专利号:CN-1209464-C
    优先权日:1996-04-19
    标 题 :Synthesis of poly deoxynucleosides, synthesis of chromosome DNA, and method for preparing chromosome

    专利号:CN-105879906-A
    优先权日:2015-08-19
    标 题 :Ionic liquid catalyst for catalytic synthesis of microbial diesel and method for catalytic synthesis of microbial diesel

    专利号:CN-1177008-A
    优先权日:1996-04-19
    标题:Synthesis of poly deoxynucleosides, synthesis of chromosome DNA, and method for preparing chromosome

    专利号:CN-106635880-A
    优先权日:2016-11-02
    标 题:Escherichia coli mutant strain resistant to phenyl lactic acid, application in synthesis of phenyl lactic acid and synthesis method thereof

    专利号:CN-104762275-B
    优先权日:2015-04-15
    标题 :A kind of enzyme with the function of catalyzing the synthesis of DMAPP from DMA and its application

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Phenacetin and Thallin for Children. Ind Med Gaz. 1889 Jul;24(7):215.
    2: Robison JA. Antipyrine and Thallin. Chic Med J Exam. 1887 Jan;54(1):10-14.

    合成参考文献


    摘要:Chen, Z.-P.; Zhou, Y.-G., Science of Synthesis: Catalytic Reduction in Organic Synthesis, (2017) 1, 160.
    摘要:Li, H.; Wang, Y.; Liu, Q., Science of Synthesis: Base-Metal Catalysis, (2023) 2, 600.
    摘要:Shehzad, A.; Vu, H. D.; Devi, K.; Bissinger, B. R. G.; Wiesenfeldt, M. P., Science of Synthesis: Dearomatizations, (2026) .
    参考文献:10.1038/nchem.1506
    摘要:Over B, Wetzel S, Grütter C, Nakai Y, Renner S, Rauh D, Waldmann H. Natural-product-derived fragments for fragment-based ligand discovery. Nat Chem. 2013 Jan;5(1):21–8. doi: 10.1038/nchem.1506.
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