CAS: 117-02-2; 1,3-Dihydroxy-2-Methylanthracene-9,10-Dione

该化合物是天然产生的炭疽衍生物,主要与Rubia colifolia及相关植物隔离,它显示出显著的生物活动,包括抗炎,抗氧化剂和潜在的抗癌特性. 它的特征清晰的结构和药理效应使它成为药物开发和植物化学研究的宝贵化合物.

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上下游产品

CAS号85-44-9 苯酐 | CAS号608-25-3 2,6-二羟基甲苯 | CAS号28026-96-2 3,5-二羟基-4-甲基苯甲酸 | CAS号65-85-0 苯甲酸 | CAS号22170-89-4 1-hydroxy-3-met... | CAS号7460-43-7 甲基异茜草素-1-甲醚 | CAS号1010-60-2 2-氯-1,4-萘醌 | CAS号122305-38-8 (Z)-4-ethoxy-2,... | CAS号6971-52-4 Phenol, 3-metho... | CAS号477-84-9 丹宁卡 | CAS号7460-43-7 甲基异茜草素-1-甲醚 | CAS号7416-31-1 (4-acetyloxy-3-...

合成工艺路线路线简述

    📜1-羟基-3-甲氧基-2-甲基蒽醌置于三氯化铝体系中,化学反应生成茜根定
    参考文献:Mitter; Biswas,Journal Of The Indian Chemical Society,1930,Vol. 7,P. 839
    标题:Mitter; Biswas,Journal Of The Indian Chemical Society,1930,Vol. 7,P. 839

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    专利信息


    专利号:US-6531591-B1
    优先权日:1999-07-07
    标 题 :Synthesis of stable quinone and photoreactive ketone phosphoramidite reagents for solid phase synthesis of photoreactive-oligomer conjugates
    发明人：FENSHOLDT JEF
    权利人:EXIQON AS
    摘要:Quinone phosphoramidite reagents as well as photoreactive ketone phosphoramidite reagents, such as anthraquinone phosphoramidite reagents and benzophenone phosphoramidite reagents were synthesized and used for the solid phase synthesis of photoreactive-oligonucleotide conjugates. These phosphoramidite reagents are stable, suitable for large-scale synthesis and designed for automated solid phase synthesis of oligomers terminating in a photoreactive moiety.

    专利号:EP-1202998-B1
    优先权日:1999-07-07
    标 题 :Synthesis of stable quinone and photoreactive ketone phosphoramidite reagents for solid phase synthesis of photoreactive-oligomer conjugates
    发明人：FENSHOLDT JEF
    权利人:EXIQON AS
    摘要:Quinone phosphoramidite reagents as well as photoreactive ketone phosphoramidite reagents, such as anthraquinone phosphoramidite reagents and benzophenone phosphoramidite reagents were synthesized and used for the solid phase synthesis of photoreactive-oligonucleotide conjugates. These phosphoramidite reagents are stable, suitable for large-scale synthesis and designed for automated solid phase synthesis of oligomers terminating in a photoreactive moiety.

    专利号:EP-1202998-A1
    优先权日:1999-07-07
    标题:Synthesis of stable quinone and photoreactive ketone phosphoramidite reagents for solid phase synthesis of photoreactive-oligomer conjugates

    专利号:DE-60006680-T2
    优先权日:1999-07-07
    标题 :SYNTHESIS OF STABLE CHINONE- AND PHOTOREACTIVE KETONE-PHOSPHORAMIDITE REAGENT FOR SOLID-PHASE SYNTHESIS OF PHOTOREACTIVE OLIGOMER CONJUGATES

    专利号:WO-0104129-A1
    优先权日:1999-07-07
    标题:Synthesis of stable quinone and photoreactive ketone phosphoramidite reagents for solid phase synthesis of photoreactive-oligomer conjugates

    专利号:AU-5805900-A
    优先权日:1999-07-07
    标 题 :Synthesis of stable quinone and photoreactive ketone phosphoramidite reagents for solid phase synthesis of photoreactive-oligomer conjugates

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    合成参考文献


    摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198
    摘要:Tripathi YB, Sharma M. Comparison of the antioxidant action of the alcoholic extract of Rubia cordifolia with rubiadin. Indian J Biochem Biophys. 1998 Oct;35(5):313–6.
    参考文献:10.1016/j.toxicon.2008.03.011
    摘要:Núñez Montoya SC, Comini LR, Rumie Vittar B, Fernández IM, Rivarola VA, Cabrera JL. Phototoxic effects of Heterophyllaea pustulata (Rubiaceae). Toxicon. 2008 Jun 15;51(8):1409–15. doi: 10.1016/j.toxicon.2008.03.011.
    摘要:Huang WH, Li YB, Jiang JQ. [Chemical constituents from Hedyotis diffusa]. Zhongguo Zhong Yao Za Zhi. 2008 Mar;33(5):524–6.
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