邻氯乙苯置于盐酸,Sodium Hydroxide,对苯二酚,Zinc(II) Chloride体系中,用 二硫化碳,乙醇 用作溶剂,化学反应生成(4-乙烯基苯基)甲醇 参考文献:Chloromethylation Of β-Chloroethylbenzene And The Preparation Of P-Vinylbenzyl Alcohol1 标题:Chloromethylation Of β-Chloroethylbenzene And The Preparation Of P-Vinylbenzyl Alcohol1 摘要: Doi:10.1021/jo01066A015
专利号:US-7592392-B2 优先权日:2003-04-04 标 题 :Synthesis of functional polymers for use in organic synthesis and combinatorial chemistry 发明人:LINDSLEY CRAIG W; WISNOSKI DAVID D 权利人:MERCK & CO INC 摘要:The present invention relates to a novel process for the preparation of solid-supported scavenging reagents and solid-supported functional polymers. The invention further relates to novel solid-supported functional polymers and to their use in organic synthesis and combinatorial chemistry.
专利号:US-2009263858-A1 优先权日:2004-09-14 标 题 :Process for synthesis of mucin-type peptides and muc1-related glycopeptides 发明人:NISHIMURA SHINICHIRO; HINOU HIROSHI; FUMOTO MASATAKA 权利人:SHIONOGI & CO 摘要:The invention aims at providing novel compounds useful as primer in producing mucin-type glycopeptides which are useful in a wide field including materials for biochemical research, drugs, and food and the production of which was difficult in the prior art; and a process for the production of glycopeptides by using the primers. The aim is attained by providing novel glycopeptide derivatives (represented by the general formula (I)) which each bear an aldehyde or ketone group at the end and each contain an amino acid residue cleavable with a protease; and an easy and simple process for the production of glycopeptides by using the derivative as the primer.
专利号:US-3888844-A 优先权日:1971-09-10 标 题:Halogenated esters of phosphorus-containing acids (ii) 发明人:D ALELIO GAETANO F 权利人:ALELIO GAETANO F D 摘要:This invention deals with new phosphorus containing polymeric esters having pendent groups therein of the formula OBTAINED BY THE REACTION OF A POLYMER HAVING AT LEAST 2 AND PREFERABLY AT LEAST 4 HYDROXY GROUPS THEREIN WITH A PHOSPHORUSHALOGEN COMPOUND OF THE FORMULA XP(O) (ORCX CXR'')2 wherein: R represents a divalent hydrocarbon radical containing 1-20 carbon atoms; R'' represents X, hydrogen or R''''; R'''' represents a monovalent hydrocarbon radical containing 1-20 carbon atoms; and X represents chlorine or bromine. Somewhat related polymers are also disclosed as derived by the reaction of WHEREIN Q'' is an organic moiety, n'' has a value of at least one, n'''' is one or two, R'''''' represents hydrogen or a monovalent hydrocarbon group of 1-20 carbon atoms, and the other symbols have the same meaning as defined above. Also disclosed are the reaction products of the phosphite compound HOP(ORCX CXR'')2 with an aldehyde and an organic nitrogen compound having one or two hydrogen atoms on the nitrogen, or with a compound having an ethylenic group therein. These new ester polymers and compounds are useful particularly as fire retardants, agricultural chemicals, fuel additives, plasticizers, monomers and intermediates for the synthesis of other useful derivatives.
专利号:US-2016115113-A1 优先权日:2014-10-28 标题 :Aerobic Oxidative Esterification of Sugar-Derived 1,4-Disubstituted Benzene for Direct Synthesis of Dimethylterephthalate 发明人:SHIRAMIZU MIKA; LATTNER JAMES R; KANDEL KAPIL 权利人:EXXONMOBIL CHEM PATENTS INC 摘要:This invention relates to a dimethylterephthalate production process comprising reacting substituted furan with ethylene under cycloaddition reaction conditions and in the presence of a cycloaddition catalyst to produce a bicyclic ether, dehydrating the bicyclic ether to produce a substituted phenyl, dissolving said substituted phenyl in methanol, and oxidizing and esterifying the substituted phenyl in the presence of an oxidative esterification catalyst to form dimethylterephthalate. Importantly, the process does not include oxidizing the substituted phenyl to form terephthalic acid.
专利号:US-6803447-B2 优先权日:2002-08-16 标题:Preparation of supramolecular polymers by copolymerization of monomers containing quadruple hydrogen bonding units with regular monomers 发明人:JANSSEN HENRICUS MARIE; VAN GEMERT GABY MARIA LEONARDA; TEN CATE AAFKE TESSA; VAN BEEK DIMPHNA JOHANNA MARIA; SIJBESMA RINTJE PIETER; MEIJER EGBERT WILLEM; BOSMAN ANTON WILLEM 权利人:EUTECHPARK MMP1 28 摘要:The invention relates to the synthesis of polymers containing self-complementary quadruple hydrogen groups by copolymerizing monomers containing a quadruple hydrogen bonding group with one or more monomers of choice. The resulting polymers show unique new characteristics due to the presence of additional physical interactions between the polymer chains that are based on multiple hydrogen bonding interactions (supramolecular interactions).
专利号:WO-0078740-A1 优先权日:1999-06-23 标 题 :Solid-supported initiators and functional polymers for use in organic synthesis and combinatorial chemistry 发明人:HARIKRISHNAN LALGUDI SANKARAN; HODGES JOHN COOKE; LINDSLEY CRAIG WILLIAM 权利人:WARNER LAMBERT CO; HARIKRISHNAN LALGUDI SANKARAN; HODGES JOHN COOKE; LINDSLEY CRAIG WILLIAM 摘要:Solid-supported initiator and functional polymers are described as well as methods for the preparation and use in solution phase, solid-phase organic synthesis, and combinational chemistry including use as initiators of solid-supported free-radical polymerization, as solid-supported scavengers for purification of crude solution phase reaction mixtures, as a stationary phase for solid-phase organic synthesis, and as solid-supported reagents in solution-phase organic synthesis.