CAS: 6909-93-9; 4-Methylpyridine-2,5-Diamine

该化合物是一种环环环有机化合物,其特点是氨基代代丙烯核心,在4点位置有一个甲基组,这种结构具有独特的反应性,使其成为制药和农用化学合成中有价值的中间体,其双重性能允许多用途衍生,能够形成复杂的异丙环或与金属中心进行协调.甲基组增强溶性并影响电子特性,便于在催化或材料科学中进行量身定制的应用.高纯度能确保研究和工业过程的一贯性.由于对空气或湿度的潜在敏感性,因此建议谨慎处理.

结构式图片

相似化合物

21901-40-6 53929-59-2 6992-84-3

上下游产品

CAS号21901-40-6 2-氨基-4-甲基-5-硝基吡啶 | CAS号7772-99-8 无水氯化亚锡 | CAS号179555-04-5 5-乙酰基氨基-2-氨基-4-甲基吡啶

合成工艺路线路线简述

    📜2-氨基-4-甲基-5-硝基吡啶置于palladium 10% On Activated Carbon,氢气体系中,用 四氢呋喃 作为反应溶剂,化学反应 3.0H,以3.2 G的收率获得产物4-甲基-2,5-二氨基吡啶
    参考文献:Inhibitors Of Hepatitis C Virus Replication
    标题:Inhibitors Of Hepatitis C Virus Replication
    摘要:本发明涉及一种具有式(i)的化合物,该化合物可用作丙型肝炎病毒(hcv)ns5A抑制剂,以及该类化合物的合成,以及利用该类化合物抑制hcv Ns5A活性,用于治疗或预防hcv感染,以及在基于细胞的系统中抑制hcv病毒复制和/或病毒产生.

    海关参考信息

    专利信息


    专利号:US-2022356182-A1
    优先权日:2009-03-27
    标题 :Inhibitors of hepatitis c virus replication
    发明人:COBURN CRAIG A; LUDMERER STEVEN W; LIU KUN; WU HAO; SOLL RICHARD; ZHONG BIN; ZHU JIAN
    权利人:MERCK SHARP & DOHME
    摘要:The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

    专利号:US-11053243-B2
    优先权日:2009-03-27
    标 题:Inhibitors of hepatitis C virus replication
    发明人:COBURN CRAIG A; LUDMERER STEVEN W; LIU KUN; WU HAO; SOIL RICHARD; ZHONG BIN; ZHU JIAN
    权利人:MERCK SHARP & DOHME
    摘要:The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

    专利号:US-9090661-B2
    优先权日:2009-03-27
    标 题:Inhibitors of hepatitis C virus replication
    发明人:COBURN CRAIG A; MCCAULEY JOHN A; LUDMERER STEVEN W; LIU KUN; VACCA JOSEPH P; WU HAO; HU BIN; SOLL RICHARD; SUN FEI; WANG XINGHAI; YAN MAN; ZHANG CHENGREN; ZHENG MINGWEI; ZHONG BIN; ZHU JIAN
    权利人:MERCK SHARP & DOHME
    摘要:The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    参考标题: Inhibitors Of Hepatitis C Virus Replication Inhibiteurs De La Réplication Du Virus De L'Hépatite C
    摘要:The Present Invention Relates To Compounds Of Formula (I) That Are Useful As Hepatitis C Virus (Hcv) Ns5A Inhibitors, The Synthesis Of Such Compounds, And The Use Of Such Compounds For Inhibiting Hcv Ns5A Activity, For Treating Or Preventing Hcv Infections And For Inhibiting Hcv Viral Replication And/or Viral Production In A Cell-Based System.
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知