CAS: 538-81-8; (1E,3E)-1,4-Diphenylbuta-1,3-Diene

上下游产品

(E)-3-phenylpropenal methanol sodium methylate benzyltriphenylphosphonium chloride4,7-diphenyl-2-benzofuran-1,3-dione non-3-ene-7,9-dionecis-2,5-diphenyl-8-oxabicyclo4.3.0non-3-ene-7,9-dione phenyl[1, 1'; 4', 1'']terphenyl-2'-yl-methanone 4-nitro-3,5,6-triphenyl-cyclohexene

📜苯乙烯置于bis(Cyclopentadienyl)Dihydrozirconium,Copper Diacetate体系中,用 乙醇,N,N-二甲基甲酰胺,甲苯 作为反应溶剂,化学反应 8.0H,反应生成 1,4-二苯基-1,3丁二烯
参考文献:锆催化剂促成的h2-无受体脱氢硼酸化和烯烃转移硼酸化.
标题:锆催化剂促成的h2-无受体脱氢硼酸化和烯烃转移硼酸化.
摘要:使用锆催化剂获得了用于乙烯基硼酸酯合成的烯烃的有效且直接的脱氢硼酸化的第一个例子.我们的方法避免了使用宝贵的过渡金属,额外的氢受体,高温和长反应时间,而这是克服硼烷还原烷基硼酸酯所必需的.详细的机理研究揭示了可逆的反应途径,并进一步建议将锆配合物用作转移硼酸化的"穿梭催化剂",从而避开了相对敏感的硼烷的使用.
DOI:10.1002/anie.201908931

专利信息

专利号:US-2003162992-A1
优先权日:2001-12-14
标 题 :Preparation of intermediates useful in the synthesis of antiviral nucleosides
发明人：WATANABE KYOICHI A; DU JINFA
摘要:The present invention is an efficient process for the manufacture of α-acyloxyacetaldehyde, a key intermediate in the synthesis of 1,3-oxathiolane and 1,3-dioxolane nucleosides.

专利号:WO-9847910-A1
优先权日:1997-04-21
标题:Method for solution phase synthesis of oligonucleotides
发明人：PIEKEN WOLFGANG; MCGEE DANNY; SETTLE ALECIA; ZHAI YANSHENG; HUANG JIANPING; HILL KEN; SMITH RANDALL S
权利人:NEXSTAR PHARMACEUTICALS INC; PIEKEN WOLFGANG; MCGEE DANNY; SETTLE ALECIA; ZHAI YANSHENG; HUANG JIANPING; HILL KEN; SMITH RANDALL S
摘要:This invention discloses an improved method for the sequential solution phase synthesis of oligonucleotides. The method lends itself to automation and is ideally suited for large scale manufacture oligonucleotides with high efficiency.

专利号:US-6479599-B1
优先权日:1997-04-04
标题:Catalyst system for high yield synthesis of polyolefins
发明人：PEIL KEVIN P; WILSON DAVID R
权利人:BP CHEM INT LTD
摘要:This invention relates to a supported metallocene catalyst system for the high yield synthesis of polyolefins, to methods of preparation of the catalyst system, to polymerization processes which use the catalyst system and to polyolefin polymers produced by the polymerization processes.

专利号:US-5498734-A
优先权日:1991-09-23
标 题:Preparation and use of (2-butene-1,4-diyl)magnesium complexes in organic synthesis
发明人：RIEKE REUBEN D
权利人:UNIV NEBRASKA
摘要:The magnesium complexes of cyclic hydrocarbons containing conjugated dienes, such as 1,2-dimethylenecycloalkanes, and 1,3-butadienes, are readily prepared in high yields using highly reactive magnesium. Reactions of these (2-butene-1,4 diyl)magnesium reagents with electrophiles such as dibromoalkanes, alkylditosylates, alkylditriflates, bromoalkylnitriles, esters, or amides serve as a convenient method for synthesizing carbocyclic systems. Significantly, carbocycles prepared by this method contain functional groups such as the exocyclic double bond or a keto group in one of the rings which could be used for further elaboration of these molecules. Furthermore, fused bicyclic systems containing a substituted five-membered ring can be conveniently prepared at high temperatures by the reactions of (2-butene-1,4-diyl)magnesium complexes with carboxylic esters or acid halides whereas low temperatures lead to regioselective synthesis of β,γ-unsaturated ketones. Additionally, γ-lactones, including spiro γ-lactones, can be easily prepared in a one pot synthesis from the reaction of (2-butene-1,4-diyl)magnesium complexes with a ketone or aldehyde and carbon dioxide. Also, δ-lactones can be easily prepared in a one pot synthesis from the reaction of (2-butene-1,4-diyl)magnesium complexes with epoxides followed by reaction with CO 2 . Use of α-hydroxy epoxides without the addition of CO 2 leads to the synthesis of vicinal diols. Chiral epoxides lead to chiral alcohols.

专利号:US-5581004-A
优先权日:1991-09-23
标题 :Preparation and use of (2-butene-1,4-diyl) magnesium complexes in organic synthesis
发明人：RIEKE REUBEN D
权利人:UNIV NEBRASKA
摘要:The magnesium complexes of cyclic hydrocarbons and conjugated dienes, such as 1,2-dimethylenecycloalkanes and 1,3-butadienes, are readily prepared in high yields using highly reactive magnesium. Reactions of these (2-butene-1,4-diyl)magnesium reagents with electrophiles such as dibromoalkanes, alkylditosylates, alkylditriflates, bromoalkylnitriles, esters, or amides serve as a convenient method for synthesizing carbocyclic systems. Significantly, carbocycles prepared by this method contain functional groups such as the exocyclic double bond or a keto group in one of the rings which could be used for further elaboration of these molecules. Furthermore, fused bicyclic systems containing a substituted five-membered ring can be conveniently prepared at high temperatures by the reactions of (2-butene-1,4-diyl)magnesium complexes with carboxylic esters or acid halides whereas low temperatures lead to regioselective synthesis of β,γ-unsaturated ketones. Additionally, γ-lactones, including spiro γ-lactones, can be easily prepared in a one pot synthesis from the reaction of (2-butene-1,4-diyl)magnesium complexes with a ketone or aldehyde and carbon dioxide.

专利号:US-12006540-B2
优先权日:2015-09-28
标题:Synthesis of novel disulfide linker based nucleotides as reversible terminators for DNA sequencing by synthesis
发明人：JU JINGYUE; LI XIAOXU; CHEN XIN; LI ZENGMIN; KUMAR SHIV; SHI SHUNDI; GUO CHENG; REN JIANYI; HSIEH MIN-KANG; CHIEN MINCHEN; TAO CHUANJUAN; ERTURK ECE; KALACHIKOV SERGEY; RUSSO JAMES J
权利人:UNIV COLUMBIA
摘要:Disclosed herein, inter alia, are compounds, compositions, and methods of use thereof in the sequencing of a nucleic acid.