CAS: 4920-77-8; 2-Nitro-3-Methylphenol

上下游产品

5-hydroxy-6-nitro-toluene-2,4-disulfonyl chloride 5-methoxy-6-nitro-toluene-2,4-disulfonyl chloride 3-methyl-phenol 2,3-epoxy-3-methylcyclohexanone 2-amino-3-methylphenol acetic acid-(3-methyl-2-nitro-phenyl ester) 1-(benzyloxy)-3-methyl-2-nitrobenzene (3-methyl-2-nitro-phenoxy)-acetic acid

间甲酚置于硫酸,硝酸体系中,化学反应 2.0H,以75%的收率获得产物2-硝基-3-甲基苯酚
参考文献:Design,Synthesis And Anticancer Activity Evaluation Of Diazepinomicin Derivatives
标题:Design,Synthesis And Anticancer Activity Evaluation Of Diazepinomicin Derivatives
摘要:合成了一系列地西泮米辛衍生物,并在体外评估了其对人类癌瘤细胞系的生长抑制活性.结果表明这种化合物具有抗癌选择性.根据结果,讨论了初步的结构-活性关系.
DOI:10.2174/1570180811310040011

专利信息

专利号:US-4764263-A
优先权日:1987-05-18
标 题:Electrochemical synthesis of substituted aromatic amines in basic media
发明人：GREGORY THOMAS D; STUTTS KENNETH J
权利人:DOW CHEMICAL CO
摘要:Substituted amino aromatic compounds such as 3-amino-4-hydroxybenzoic acid are prepared by electrolytically reducing the corresponding nitro aromatic compound in a basic medium at temperatures below 60° C. and current densities greater than 50 milliamps per square centimeter. The aminohydroxybenzoic acids are useful in the preparation of polybenzoxazoles which are used to make fibers and composites having high strength and thermal stability.

专利号:WO-9729091-A1
优先权日:1996-02-09
标题:Balanol analogues
发明人：NIELSEN JOHN; LYNGSOE LARS OLE
权利人:AUDA PHARMACEUTICALS APS; NIELSEN JOHN; LYNGSOE LARS OLE
摘要:The present invention relates to a solid phase methodology for the preparation of a combinatorial library of structural analogues of the natural product balanol (ophiocordin, azepinostatin), which is a protein kinase C (PKC) and protein kinase A (PKA) inhibitor. The method comprises solid-phase synthesis of the analog variants of balanol whereby a high molecular diversity is introduced. The synthetic scheme is based on a retrosynthetic analysis of the native structure which revealed three main building blocks suitable as templates for modification. The dicarboxy-functional moiety can be immobilised to the polymer support either as the monoallyl ester or as the internal anhydride. The libraries produced by the method are especially suited for high throughput screening of potential drug candidates for the treatment of mammals, especially humans.

专利号:FI-86563-C
优先权日:1987-05-18
标题:Electrochemical synthesis of substituted amines in basic media

专利号:JP-2651230-B2
优先权日:1987-05-18
标 题 :Electrochemical synthesis of substituted aromatic amines in basic media

专利号:US-2006211603-A1
优先权日:2004-08-18
标 题:Ramoplanin derivatives possessing antibacterial activity
发明人：RAJU BORE G; CIABATTI ROMEO; MAFFIOLI SONIA I; SINGH UPINDER; ROMANO GABRIELLA; MICHELUCCI ELENA; TISENI PAOLO S; CANDIANI GIANPAOLO; KIM BUM; O'DOWD HARDWIN
权利人:VICURON PHARM INC
摘要:Novel ramoplanin derivatives are disclosed. These ramoplanin derivatives exhibit antibacterial activity. As the compounds of the subject invention exhibit potent activities against gram positive bacteria, they are useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.