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N-tert-butoxycarbonyl-L-methionine2B°C-Met(O)-Asp(OBzl)-Phe-NH2 112H140Cl2N14O22S2C112H140Cl2N14O22S2 L-methionine gastrin-5 海关参考信息
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专利信息
专利号:US-2004110228-A1
优先权日:2002-04-01
标 题:Combinatorial organic synthesis of unique biologically active compounds
发明人:MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.
专利号:EP-0193910-A2
优先权日:1985-03-06
标题:Synthesis of a derivative of GRF and intermediate peptides
专利号:US-4507230-A
优先权日:1982-05-12
标 题 :Peptide synthesis reagents and method of use
发明人:TAM JAMES P; HEATH JR WILLIAM F; MERRIFIELD ROBERT B
权利人:RESEARCH CORP
摘要:A method of releasing a functional group present in an amino acid or amino acyl residue from a resin or protecting residue which is bonded to the functional group by a linkage having proton affinity, which comprises: reacting the functional group bonded to the organic residue, with a mixture of HF and a base for a time and under conditions effective to produce the release; wherein the amounts of HF and base in the mixture are adjusted so that said release occurs substantially by an SN2 mechanism.
专利号:CN-106928313-B
优先权日:2015-12-31
标题 :Synthesis method of C-terminal modified peptide
专利号:WO-2009000950-A1
优先权日:2007-06-25
标题:Method for the deblocking/deprotection of compounds obtained by solid phase synthesis