CAS: 28177-48-2; 2,6-Difluorophenol

上下游产品

CAS号1228447-86-6 (2,6-difluoroph... | CAS号437-82-1 2,6-二氟苯甲醚 | CAS号437-81-0 2,6-二氟苯甲醛 | CAS号162101-25-9 2,6-二氟苯硼酸 | CAS号372-18-9 1,3-二氟苯 | CAS号363-47-3 3,5-二氟-4-甲氧基苯胺 | CAS号437-82-1 2,6-二氟苯甲醚 | CAS号486424-36-6 1-溴-2,5-二氟-4-羟基苯 | CAS号392-25-6 2,6-二氟-4-硝基苯甲醚 | CAS号2362-50-7 噻蒽5-氧化物 | CAS号139656-65-8 5-(4-hydroxy-3,... | CAS号92-85-3 噻蒽 | CAS号554-84-7 3-硝基苯酚 | CAS号36914-78-0 (2,6-difluoroph... | CAS号619-08-9 2-氯-4-硝基酚

2,6-二氟苯甲醚置于盐酸,三(五氟苯基)硼烷体系中,用 乙醇,正己烷,水 用作溶剂,化学反应 1.52H,反应生成2,6-二氟苯酚
参考文献:芳基烷基醚的快速温和裂解以释放酚类
标题:芳基烷基醚的快速温和裂解以释放酚类
摘要:使用三(五氟苯基)硼烷通过 Piers-Rubinsztajn 反应实现芳基烷基醚的温和,快速和有效的去甲基化.这种两步脱保护允许烷基醚用作有效的苯酚保护基团,而不需要苛刻的脱保护条件.
Doi:10.1002/ejoc.202200570

专利信息

专利号:WO-2025149479-A1
优先权日:2024-01-12
标题:Synthesis of modified nucleoside triphosphates
发明人：KUCHELMEISTER HANNES; PFAFFENEDER TONI; MEX MARTIN; VETH SIMON; MENKE JAN-MICHAEL
权利人:ROCHE DIAGNOSTICS GMBH
摘要:The invention relates to a new diastereoselective synthesis method for highly modified nucleoside triphosphates with two conjugable groups. The method works in liquid phase with conventional laboratory equipment as used in any chemical laboratory or production. For this, a new chiral P(V) phosphorylation reagent has been designed that allows highly efficient diastereoselective synthesis under mild conditions. Overall, a highly efficient, diastereoselective, high quality, cost-effective synthetic method of modified nucleoside triphosphates has been developed.

专利号:US-2004110228-A1
优先权日:2002-04-01
标 题:Combinatorial organic synthesis of unique biologically active compounds
发明人：MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.

专利号:US-2015158809-A9
优先权日:2013-02-26
标 题 :Method of making 1-(acyloxy)-alkyl carbamate compounds
发明人：WANG HUAN; LIU PENG; DAI QUNYING; YIN HAO; RAILLARD STEPHEN P
权利人:XENOPORT INC
摘要:Methods of preparing carbamate prodrugs of amine-containing drugs are provided. Carbonates useful in the synthesis of the carbamate prodrugs are also provided.

专利号:US-6689919-B1
优先权日:1999-09-22
标 题 :Catalysts for oxidative polymerization of fluorophenol, method of oxidative polymerization of fluorophenol, and poly(oxyfluorophenylene) derivative
发明人：TSUCHIDA EISHUN; OYAIZU KENICHI; KUMAKI YOSUKE; SAITO KEI
权利人:JAPAN SCIENCE & TECH CORP
摘要:The synthesis of fluoropolyarylene ether with a high degree of polymerization is enabled, by using a copper complex catalyst with an oxidation potential in the range of -1V to 2V, for the oxidative polymerization of fluorophenols that contain at least one hydrogen atom as well as a fluorine atom bonded to the carbon atoms constituting the benzene ring.

专利号:US-2012115907-A1
优先权日:2009-04-24
标题 :Novel compounds as inhibitors of renin
发明人：THOMBARE PRAVAIN; DESAI JIGAR; JAIN MUKUL R
权利人:THOMBARE PRAVAIN; DESAI JIGAR; JAIN MUKUL R; CADILA HEALTHCARE LTD
摘要:The present invention relates to novel renin inhibitors of general formula (1), novel intermediates involved in their synthesis, their pharmaceutically acceptable salts and pharmaceutical compositions containing them. The present invention also relates to a process of preparing compounds of general formula (1), their tautomeric forms, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, and novel intermediates involved in their synthesis.

专利号:US-9751851-B2
优先权日:2013-09-20
标 题:Molecules and compositions that inhibit gram negative bacteria and their uses
发明人：BASSLER BONNIE L; SEMMELHACK MARTIN F; DRESCHER KNUT; SIRYAPORN ALBERT; CONRAD-MILLER LAURA C; O'LOUGHLIN COLLEEN T
权利人:UNIV PRINCETON; BASSLER BONNIE L; SEMMELHACK MARTIN F; DRESCHER KNUT; SIRYAPORN ALBERT; MILLER LAURA C; O'LOUGHLIN COLLEEN T
摘要:Antivirulence strategies to combat Pseudomonas aeruginosa , are described. One strategy encompasses synthesis of a series of compounds that inhibit the production of pyocyanin, a redox-active virulence factor produced by this pathogen. A related strategy encompasses synthesis of compounds that inhibit the two P. aeruginosa quorum-sensing receptors, LasR and RhlR, inhibit production of pyocyanin, and inhibit biofilm formation.