CAS: 23405-15-4; 2,5-Dioxopyrrolidin-1-Yl Benzoate

该化合物是一种化学化合物,通常用于生物合成和浸泡物合成.该化合物的特点是与N-Hydroxsucciniide(NHS)组相连的苯并酸碱,众所周知,该组有能力与初级氨基胺形成稳定的氨化结.NHIS酯在生物化学应用中特别有用,因为它具有反应性,而且能够促进蛋白质和浸渍物等生物分子的聚合,而不需要苛刻条件.该复合物一般是白色至白色的固态,在二甲基硫氧化物和二甲基二亚硫化物(DMF)等有机溶剂中可溶解.其再活动允许选择性地标注和修改生物分子,使其成为药物开发,诊断和研究的有用工具.在处理该化合物时,应当注意安全防范措施,因为它可能会对皮肤和眼睛产生刺激.

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CAS号6066-82-6 N-羟基琥珀酰亚胺 | CAS号65-85-0 苯甲酸 | CAS号532-32-1 苯甲酸钠 | CAS号591-50-4 碘苯 | CAS号201230-82-2 carbon monoxide | CAS号100-51-6 苯甲醇 | CAS号17763-67-6 三氟甲烷磺酰苯 | CAS号100-52-7 苯甲醛 | CAS号108-86-1 溴苯 | CAS号98-88-4 苯甲酰氯 | CAS号3278-14-6 N-苯乙基-苯甲酰胺 | CAS号1464-98-8 N-(丙-2-炔-1-基)苯甲酰胺 | CAS号495-69-2 马尿酸 | CAS号6066-82-6 N-羟基琥珀酰亚胺 | CAS号68388-03-4 N-(3-benzamidop... | CAS号6108-74-3 Benzamide,N-(3-... | CAS号93-98-1 N-苯甲酰替苯胺 | CAS号776-75-0 1-苯甲酰哌啶 | CAS号1485-70-7 N-苄基苯甲酰胺 | CAS号6094-36-6 N-苯甲酰-L-谷氨酸

合成工艺路线路线简述

    📜苯甲醛置于n-羟基丁二酰亚胺,氧气,Cobalt(II) Diacetate Tetrahydrate,碳酸氢钠体系中,用 乙腈 用作溶剂,20.0 °C,101.33 Kpa 条件下,反应 1.0H,反应生成N-(苯甲酸基)丁二酰亚胺
    参考文献:与n-羟基琥珀酰亚胺的好氧酰胺键形成
    标题:与n-羟基琥珀酰亚胺的好氧酰胺键形成
    摘要:轻松呼吸:分子氧是最丰富,原子效率最高且最经济的氧化剂之一.据报道,由醛和胺形成的好氧氧化酰胺.该方法使用催化量的co(oac)2和n-羟基琥珀酰亚胺作为反应促进剂.它适用于手性底物,而不会损失其光学纯度.
    Doi:10.1002/asia.201200017

    海关参考信息

    专利信息


    专利号:US-2004030209-A1
    优先权日:2000-11-30
    标 题:Method for the production of alkyl aryl sulphonates
    发明人:NARBESHUBER THOMAS; STEINBRENNER ULRICH; KRACK GERHARD
    摘要:The preparation of alkylaryl compounds takes place by n 1) preparation of a mixture of, on statistical average, predominantly monobranched C 10-14 -olefins by n a) reaction of a C 4 -olefin mixture over a metathesis catalyst for the preparation of an olefin mixture comprising 2-pentene and/or 3-hexene, and optional removal of 2-pentene and/or 3-hexene, followed by dimerization of the resulting 2-pentene and/or 3-hexene over a dimerization catalyst to give a mixture comprising C 10-12 -olefins, and optionally removal of the C 10-12 -olefins, or n b) extraction of predominantly monobranched paraffins from kerosene cuts and subsequent dehydrogenation, or n c) Fischer-Tropsch synthesis of olefins or paraffins, where the paraffins are dehydrogenated, or n d) dimerization of shorter-chain internal olefins, or n e) isomerization of linear olefins or paraffins, where the isomerized paraffins are dehydrogenated, n 2) reaction of the olefin mixture obtained in stage 1) with an aromatic hydrocarbon in the presence of an alkylation catalyst which contains zeolites of the faujasite type.

    专利号:WO-9209300-A1
    优先权日:1990-11-21
    标 题:Synthesis of equimolar multiple oligomer mixtures, especially of oligopeptide mixtures

    专利号:EP-0558671-A4
    优先权日:1990-11-21
    标题 :Synthesis of equimolar multiple oligomer mixtures, especially of oligopeptide mixtures

    专利号:EP-0558671-A1
    优先权日:1990-11-21
    标 题 :Synthesis of equimolar multiple oligomer mixtures, especially of oligopeptide mixtures

    专利号:US-5556762-A
    优先权日:1990-11-21
    标题:Scanning synthetic peptide combinatorial libraries: oligopeptide mixture sets having a one predetermined residue at a single, predetermined position, methods of making and using the same
    发明人:PINILLA CLEMENCIA; APPEL JR JON R; HOUGHTEN RICHARD A
    权利人:HOUGHTEN PHARMACEUTICAL INC
    摘要:Synthetic peptide combinatorial libraries (sets) having a single, predetermined amino acid residue at a single, predetermined oligopeptide chain position and mixtures of amino acid residues at the other chain positions are disclosed, as are their processes of synthesis and use in determining the amino acid residue sequence of an oligopeptide ligand that binds to an acceptor molecule.

    专利号:EP-0558671-B1
    优先权日:1990-11-21
    标 题 :Synthesis of equimolar multiple oligomer mixtures, especially of oligopeptide mixtures

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Li, Y.; Fang, X.; Wang, Y., Science of Synthesis: DNA-Encoded Libraries, (2024) nan, 81.
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