CAS: 18293-54-4; 1-(Trimethylsilyl)-1H-1,2,4-Triazole

上下游产品

CAS号288-88-0 1,2,4-三氮唑 | CAS号75-77-4 三甲基氯硅烷 | CAS号999-97-3 六甲基二硅氮烷 | CAS号54230-60-3 1-(2,4,6-三异丙基苯磺... | CAS号122967-52-6 Me2B(μ-1,2,4-tr... | CAS号2857-97-8 三甲基溴硅烷 | CAS号288-88-0 1,2,4-三氮唑 | CAS号107-46-0 六甲基二硅氧烷 | CAS号73844-90-3 1-methylthiomet... | CAS号15625-88-4 1-(1H-1, 2, 4-三... | CAS号13578-51-3 1-对甲苯磺酰基-1,2,4-三唑 | CAS号75-77-4 三甲基氯硅烷 | CAS号112809-51-5 来曲唑

📜1H-1,2,4-三唑 反应生成1-(三甲硅基)-1H-1,2,4-三唑
参考文献: Process And Intermediate Of Letrozole[fr] Procédé Et Produit Intermédiaire Du Létrozole
标题: Process And Intermediate Of Letrozole[fr] Procédé Et Produit Intermédiaire Du Létrozole
摘要:本发明涉及一种利用新的i式中间体制备来曲唑的方法.

专利信息

专利号:US-6380378-B1
优先权日:1998-12-24
标 题:Nucleotide compound, nucleotide block oligonucleotide, and method for producing them
发明人：KITAMURA AKINORI; HORIE YOJI; UCHIDA TAKAYOSHI; YOSHIDA TADAO
权利人:TOAGOSEI COMPANY LTD
摘要:Novel nucleotide compounds represented by the formula (I)wherein R1 represents a protective group or a PEG bearing organic group; R2, R2', R2'', R3, R3' and R3'' each represents a hydrogen atom or an alkyl, cycloalkyl, aryl or aralkyl group which may contain a hetero-atom; B1, B2, B3 and B4 each represents a base, if necessary, protected by a protective group common in nucleotide chemistry or by a PEG bearing organic group; X, X' and X'' each represents an oxygen atom or a sulfur atom; Y represents an azolyl group, a mono- or di-alkylamino group or a saturated nitrogenous heterocyclic ring; A1, A2, A3 and A4 each represents a hydrogen atom, a hydroxyl group, an alkoxy group or a trialkylsilyloxy group; and m and n each represents 0 or an integer of 1 to 100. The nucleotide of the formula (I) can be used as it is in a reaction mixture for further reaction with 3'-O- and 5'-O-unprotected nucleoside or nucleotide of the formula (II) to yield a nucleotide block or oligonucleotide, and thus is useful as in situ DNA synthesis reagents.