CAS: 15128-82-2; 2-Nitropyridin-3-Ol

相似化合物

16867-03-1 20265-37-6 15128-89-9

上下游产品

CAS号74037-50-6 3-乙氧基-2-硝基吡啶 | CAS号109-00-2 3-羟基吡啶 | CAS号1111637-77-4 3-(二氟甲氧基)-2-硝基吡啶 | CAS号106840-72-6 ethyl N-(3-hydr... | CAS号337463-88-4 L-4-氰基苯丙氨酸 | CAS号39968-33-7 1-羟基-7-偶氮苯并三氮唑(HOAt) | CAS号152170-29-1 噻唑并[4,5-b]吡啶-2(3H)-酮 | CAS号443956-08-9 6-溴-2-硝基吡啶-3-醇 | CAS号209530-92-7 1-AZETIDINECARB... | CAS号74037-50-6 3-乙氧基-2-硝基吡啶 | CAS号52092-47-4 2-硝基-5-氯吡啶 | CAS号6636-78-8 2-氯-3-羟基吡啶

3-羟基吡啶置于aluminium Trinitrate体系中,用 乙腈 用作溶剂,以60%的收率获得3-羟基-2-硝基吡啶
参考文献:碘(III)通过非布朗斯台德酸性no 2 +生成的苯酚亲电硝化
标题:碘(III)通过非布朗斯台德酸性no 2 +生成的苯酚亲电硝化
摘要:使用碘基苯作为基于碘(III)和硝酸铝作为硝基基团来源的有机催化剂,开发了用于苯酚亲电硝化的第一个催化程序.该原子经济方案发生在温和的,非布朗斯台德酸性和开放式烧瓶反应条件下,具有宽泛的官能团耐受性,包括多个杂环.(smd:Mecn)mo8-Hx /(lanlo8 + F,6-311 + G *)水平的密度泛函理论(dft)计算表明反应通过阳离子途径进行,该途径有效地产生了no 2 +离子,从而是中性条件下的硝化物种.
Doi:10.1021/acs.Orglett.8B04141

专利信息

专利号:US-7465842-B2
优先权日:2004-08-26
标 题 :Enantioselective biotransformation for preparation of protein tyrosine kinase inhibitor intermediates
发明人：KUNG PEI-PEI; MARTINEZ CARLOS; TAO JUNHUA
权利人:AGOURON PHARMA
摘要:The invention relates to biocatalytic methods for preparing enantiomerically pure stereoisomers of 1-(2,6-dichloro-3-fluorophenyl)ethanol. Disclosed are methods of preparation of the desired (S)-enantiomer, which methods are based on a combination of enzymatic resolution, chemical esterification and chemical hydrolysis with inversion of 1-(2,6-dichloro-3-fluorophenyl)ethyl esters or stereoselective bio-reduction of 2,6-dichloro-3-fluoro-acetophenone with a biocatalyst such as an enzyme or a microorganism. The chiral (S)-enantiomer can be used in the synthesis of certain enantiomerically enriched, ether linked 2-aminopyridine compounds that potently inhibit auto-phosphorylation of human heptocyte growth factor receptor.

专利号:US-9919064-B2
优先权日:2012-08-10
标 题 :Compositions, methods, and systems for the synthesis and use of imaging agents
发明人：CESATI RICHARD R; RADEKE HEIKE S; PANDEY SURESH K; PUROHIT AJAY; ROBINSON SIMON P
权利人:LANTHEUS MEDICAL IMAGING INC
摘要:The present invention provides compounds with imaging moieties for imaging a subject. The present invention also relates to systems, compositions, and methods for the synthesis and use of imaging agents, or precursors thereof. An imaging agent precursor may be converted to an imaging agent using the methods described herein. In some cases, a composition or plurality of imaging agents is enriched in 18 F. In some cases, an imaging agent may be used to image an area of interest in a subject, including, but not limited to, the heart, cardiovascular system, cardiac vessels, brain, and other organs.

专利号:US-11401277-B2
优先权日:2017-11-29
标 题 :Anti-bacterial heterocyclic compounds and their synthesis
发明人：PEER MOHAMED SHAHUL HAMEED; BHARATHAM NAGAKUMAR; KATAGIHALLIMATH NAINESH; SHARMA SREEVALLI; NANDISHAIAH RADHA; RAMACHANDRAN VASANTHI
权利人:BUGWORKS RES INC
摘要:The invention relates to compounds of Formula I and Formula (B) along with their stereoisomers, pharmaceutically acceptable salts, complexes, hydrates, solvates, tautomers, polymorphs, racemic mixtures, optically active forms, and pharmaceutically active derivatives thereof. These compounds are useful for killing or inhibiting the growth of a microorganism selected from the group consisting of bacteria, virus, fungi, and protozoa.

专利号:US-11229713-B2
优先权日:2014-11-25
标题:Methods and compositions for 18F-radiolabeling of biologics
发明人：DONNELLY DAVID
权利人:BRISTOL MYERS SQUIBB CO
摘要:The invention relates to water soluble 18 F-prosthetic groups and the synthesis and use of 18 F-labeled biological molecules containing the 18 F-prosthetic groups for imaging various processes within the body, for detecting the location of molecules associated with disease pathology, and for monitoring disease progression are disclosed.

专利号:CN-112125841-A
优先权日:2020-10-23
标题:A new method for the synthesis of crizotinib intermediates

专利号:US-4552967-A
优先权日:1984-01-12
标 题:Process for the synthesis of intermediates in the preparation of diaminopyridines
发明人：GREENE JAMES M; LAVAGNINO EDWARD R; PIKE ANDREW J; TAYLOR EDWARD C
权利人:LILLY CO ELI
摘要:The present invention relates to a process for preparing aminonitropyridines comprising reacting an alkoxynitropyridine with ammonium acetate.