CAS: 139115-91-6; Tert-Butyl (2-(2-Hydroxyethoxy)Ethyl)Carbamate

相似化合物

1628679-52-6 85475-01-0 136533-09-0

二甘醇胺置于二碳酸二叔丁酯体系中,用 二氯甲烷 用作溶剂,化学反应 3.0H,以87.95%的收率获得2-(2-Boc-氨基乙氧基)乙醇
参考文献: Hmg-Coa Reductase Degradation Inducing Compound[fr] Composé Induisant La Dégradation De La Hmg-Coa Réductase
标题: Hmg-Coa Reductase Degradation Inducing Compound[fr] Composé Induisant La Dégradation De La Hmg-Coa Réductase
摘要:本发明涉及hmg-Coa还原酶降解诱导化合物.具体而言,本发明涉及一种双功能化合物,其中hmg-Coa还原酶结合基团和e3泛素连接酶结合基团通过化学连接剂连接.本发明还涉及一种制备这些化合物的方法,以及使用这些化合物降解hmg-Coa还原酶的方法,以及使用这些化合物预防或治疗与hmg-Coa还原酶相关疾病的方法.

专利信息

专利号:US-8450469-B2
优先权日:2008-01-21
标 题:Synthesis of peptide nucleic acids conjugated with amino acids and their application
发明人：LEE HYUNIL; MIN JUNG HYUN
权利人:LEE HYUNIL; MIN JUNG HYUN; PANAGENE INC
摘要:This invention relates to a peptide nucleic acid (PNA) oligomer which is conjugated with one or more linear-type amino acid containing a plurality of alkyleneglycols and to a synthesis method thereof. In addition, this invention related to a linear amino acid spacer in a device for detection for detecting a target gene using the PNA oligomers which is fixed on a surface of a functionalized solid support. The linear amino acid spacer contains a plurality of alkyleneglycols and maintains enough space between the solid support and PNA oligomer in the device in order to prevent the interference of the interaction between the PNA oligomer and a target gene. Furthermore, this invention relates to a PNA array, a PNA chip and a gene diagnosis kit whereof sensitivity and specificity are improved by being manufactured with the PNA conjugated with the amino acid spacer.

专利号:US-9562037-B2
优先权日:2014-02-26
标题:Synthesis and use of amine-containing flavonoids as potent anti-leishmanial agents
发明人：CHOW LARRY MING-CHEUNG; CHAN WILLIAM TAK HANG; CHAN KIN-FAI; WONG IRIS LAI KING; KAN WING-YIU
权利人:UNIV HONG KONG POLYTECHNIC
摘要:The present invention relates to novel series of amine-containing flavonoids and compositions containing the compounds, as well as the synthesis and the use of the same. The invention also relates to methods of treatment and prevention of diseases, in particular, parasitic infections including Leishmaniasis, comprising administration of the compounds.

专利号:WO-2009093821-A2
优先权日:2008-01-21
标题:Synthesis of peptide nucleic acids conjugated with amino acids and their application

专利号:US-2009286938-A1
优先权日:2008-04-30
标题 :Synthesis of hybrid block copolymers from difluoroacetate ammonium salts
发明人：SILL KEVIN N; CARDOEN GREGOIRE; BREITENKAMP KURT
权利人:INTEZYNE TECHNOLOGIES INC
摘要:The present invention provides polymerization initiators and uses thereof.

专利号:JP-2004238353-A
优先权日:2003-02-07
标题 :5-substituted pyrimidine deoxynucleotide derivative and method for synthesis of nucleic acid using the same

专利号:WO-2009093821-A9
优先权日:2008-01-21
标 题 :Synthesis of peptide nucleic acids conjugated with amino acids and their application