CAS: 10597-89-4; (R)-2-(((2R,3R,4R,5R)-2-Acetamido-4,5,6-Trihydroxy-1-Oxohexan-3-yl)Oxy)Propanoic Acid
- 英文名称(R)-2-(((2R,3R,4R,5R)-2-Acetamido-4,5,6-Trihydroxy-1-Oxohexan-3-yl)Oxy)Propanoic Acid
- 中文名称N-乙酰胞壁酸
- IUPAC名称(R)-2-(((2R,3R,4R,5R)-2-acetamido-4,5,6-trihydroxy-1-oxohexan-3-yl)oxy)propanoic acid
- 其它别名Nama; Murnac; (R)-2-(Acetylamino)-3-O-(1-Carboxyethyl)-2-Deoxy-D-Glucose; Murnac
- CAS编号10597-89-4
- MFCD编号:MFCD00221511
- EINECS号:234-214-2
- FDA UNII编号:246FXU111L
- 分子式:C11H19NO8分子量:293.27
- 产品CID: 100370
- 产品分类生物化工 → 糖类化合物 → 寡糖
物理性质
- 熔点125 °C (分解)(文献)
- 沸点696.8±55.0 °C at 760 mmHg
- 闪点375.2±31.5 °C
- 密度1.4±0.1 g/cm3
- PH:D20 +56° (10 minutes) +40° (24 hrs) (c = 0.68 in water)
- pKa:3.25±0.10(预测)
- PSA:153.39
- LogP:-0.51
- 折射率1.530
- 蒸汽压0.0±5.0 mmHg at 25°C
- 溶解性DMF: 2.5 mg/mL; DMSO: 30 mg/mL; Pbs (Ph 7.2): 10 mg/mL
- 敏感性遵照规定使用和储存则不会分解。
- 外观形态固体
- 储存条件2-8°C
- 产品应用该化合物用于确定,区分和定性N-甲酰基酸/N-亚乙酰基氯基胺因和N-苯基基酸醚的基质.
MSDS等安全信息
合成工艺路线路线简述
海关参考信息
- 2905122000-异丙醇
2905310000-1,2-乙二醇
2905320000-1,2-丙二醇
2905399001-1,3-丙二醇
2905399002-1,4-丁二醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-12123041-B2
优先权日:2018-09-21
标 题:Method for the production of amino sugar-containing products
发明人：MAERTENS JO; BAUWENS DAVID; VAN BELLEGEM WOUTER; COUSSEMENT PIETER; DUCHI DRIES; DE MEY MARJAN
权利人:UNIV GENT
摘要:A method or producing amino sugar (containing) products using metabolically engineered microorganisms is disclosed, wherein the conversion of UDP-N-acetylglucosamine to cell envelope precursors and molecules is reduced by altering the activity of enzymes involved in the synthesis of cell envelope precursors and molecules.
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Pathaw N, Gurung AB, Chrungoo NK, Bhattacharjee A, Roy SS, Ansari MA, Sharma SK. In silico molecular modelling, structural dynamics simulation and characterization of antifungal nature of β-glucosidase enzyme from Sechium edule. J Biomol Struct Dyn. 2020 Jul
15:1-9. doi: 10.1080/07391102.2020.1791956. Epub ahead of print.
84:104412. doi: 10.1016/j.meegid.2020.104412. Epub 2020 Jun 9. 70(6):3749-3754. doi: 10.1099/ijsem.0.004229. Epub 2020 Jun 10. 11(1):2848. doi: 10.1038/s41467-020-16600-2.
合成参考文献
参考文献:10.1074/jbc.m111.241414
摘要:Bernard E, Rolain T, Courtin P, Guillot A, Langella P, Hols P, Chapot-Chartier MP. Characterization of O-acetylation of N-acetylglucosamine: a novel structural variation of bacterial peptidoglycan. J Biol Chem. 2011 Jul 08;286(27):23950–8.
参考文献:10.1016/0008-6215(94)84208-6
摘要:Knirel YA, Paramonov NA, Vinogradov EV, Kochetkov NK, Sidorczyk Z, Zych K. 2-Acetamido-4-O-[(S)-1-carboxyethyl]-2-deoxy-D-glucose: a new natural isomer of N-acetylmuramic acid from the O-specific polysaccharide of Proteus penneri 35. Carbohydr Res. 1994 Jun 02;259(1):C1–3. doi: 10.1016/0008-6215(94)84208-6.
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