CAS: 103-04-8; (Phenylthio)Acetic Acid

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17277-58-6 699-12-7 7605-25-6

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CAS号3959-08-8 2-(benzenesulfi... | CAS号108-98-5 硫酚 | CAS号79-11-8 氯乙酸 | CAS号17277-58-6 (苯硫基)乙酸甲酯 | CAS号79-08-3 溴乙酸 | CAS号56377-57-2 S-phenyl 2-brom... | CAS号591-50-4 碘苯 | CAS号68-11-1 硫代乙醇酸(TGA) | CAS号109-72-8 正丁基锂 | CAS号100-68-5 茴香硫醚 | CAS号59865-82-6 2-(苯基硫代)硫代乙酰胺 | CAS号3405-88-7 (4-氯苯基巯基)乙酸 | CAS号5042-53-5 (苯基硫代)丙酮 | CAS号3959-23-7 (苯磺酰)乙酸 | CAS号3959-08-8 2-(benzenesulfi... | CAS号22446-20-4 Acetamide,2-(ph... | CAS号58992-43-1 triphenyl-l5-bi... | CAS号636-70-4 三乙胺氢溴酸盐 | CAS号100-68-5 茴香硫醚 | CAS号108-98-5 硫酚

2-苯硫基乙醇置于1-羟基环己基苯基甲酮,Sodium Hydroxide体系中,用 乙二醇二甲醚 用作溶剂,以91%的收率获得苯硫基乙酸
参考文献:通过氢原子转移将伯醇和醛氧化成羧酸
标题:通过氢原子转移将伯醇和醛氧化成羧酸
摘要:伯醇和伯醛氧化成相应的羧酸是有机合成中的基本反应.在本文中,我们报告了一种用于氧化伯醇和醛的新化学选择性工艺.这种无金属反应具有新的氧化剂,易于操作的程序,高分离产率以及即使在易受攻击的仲醇和叔丁烷亚磺酰胺存在下也具有非常好至优异的官能团耐受性的特点.
Doi:10.1021/acs.Orglett.1C02188

专利信息

专利号:US-2003004337-A1
优先权日:2000-05-04
标 题 :Efficient lactam synthesis
发明人：JUNG KYUNG WOON; YOON CHEOL HWAN
摘要:Lactams, libraries of lactams, and an efficient method of synthesizing a lactam, including a γ-lactam, in which an a-diazoacetamide of the general structure (I) is reacted under conditions promoting intramolecular C-H insertion, for example in the presence of a rhodium salt such as Rh 2 (OAc) 4 , n n n by which means lactams that are precursors in the synthesis of diverse natural and synthetic products, including pyrrolidinone compounds such as lactacystin, pramanicin, kainic acid, statine, AHPPA, and rolipram, are produced.

专利号:US-6689890-B2
优先权日:2000-05-04
标 题:Efficient lactam synthesis
发明人：JUNG KYUNG WOON; YOON CHEOL HWAN
权利人:UNIV SOUTH FLORIDA
摘要:Lactams, libraries of lactams, and an efficient method of synthesizing a lactam, including a gamma-lactam, in which an alpha-diazoacetamide of the general structure (I) is reacted under conditions promoting intramolecular C-H insertion, for example in the presence of a rhodium salt such as Rh2(OAc)4,by which means lactams that are precursors in the synthesis of diverse natural and synthetic products, including pyrrolidinone compounds such as lactacystin, pramanicin, kainic acid, statine, AHPPA, and rolipram, are produced.

专利号:US-7390801-B2
优先权日:1996-12-23
标题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
发明人：THORSETT EUGENE D; PLEISS MICHAEL A; LATIMER LEE H; JOHN VARGHESE; FREEDMAN STEPHEN; BRITTON THOMAS C; AUDIA JAMES A; REEL JON K; DRESSMAN BRUCE A; DROSTE JAMES J; HENRY STEVEN S; STUCKY RUSSELL D; PORTER WARREN J
权利人:ATHENA NEUROSCIENCES INC; LILLY CO ELI
摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

专利号:US-4803280-A
优先权日:1986-07-08
标题:Substituted 1,2,3-thia-diazole-4-thiolates
发明人：LEE VING J; CURRAN WILLIAM V
权利人:AMERICAN CYANAMID CO
摘要:Intermediates useful for synthesis of cephalosporins are disclosed, which intermediates are concerned with 1,2,3-thiadiazole-4-thiolates and the preparation of such thiolates.

专利号:US-6562844-B2
优先权日:1998-01-23
标 题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
发明人：GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
权利人:UPJOHN CO
摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

专利号:EA-002100-B1
优先权日:1996-12-23
标题:CYCLOALCYL COMPOUNDS, LACTAMS, LACTONES AND RELATED COMPOUNDS CONTAINING THEIR PHARMACEUTICAL COMPOSITIONS AND METHODS OF INHIBITING THE SURVIVAL AND / OR SYNTHESIS OF β-AMYLOUS PEPTIDE SOFTWARE AGREED SOFTWARE, SOFTWARE, SOFTWARE, SOFTWARE, SOFTWARE, SOFTWARE, SOFTWARE, SOFTWARE, SOFTWARE, SOFTWARE, SOFTWARE AND SOFTWORK