CAS: 69257-04-1; (2S,4S,5R)-1-Benzyl-2-((R)-Hydroxy(Quinolin-4-yl)Methyl)-5-Vinylquinuclidin-1-Ium Chloride

相似化合物

69221-14-3 95088-20-3 67174-25-8

上下游产品

benzyl chloride CinchonidinN-9-benzylcinchonidinium p-vinylbenzoate

📜氯化苄,辛可尼丁 以 四氢呋喃 作为反应溶剂,化学反应生成 N-苄基氯化辛可宁丁
参考文献:外消旋 1,1'-联萘-2,2'-二醇 (Binol) 的动态热力学拆分
标题:外消旋 1,1'-联萘-2,2'-二醇 (Binol) 的动态热力学拆分
摘要:报道了一种以 100% 理论产率将 (R / S)-Binol(1,1'-联萘-2,2'-二醇)转化为 (R)-Binol 的动态热力学拆分方法.该技术涉及将 (R / S)-Binol 与n-苄基辛可尼丁溴化物(1 当量)和 [cu 2 (Tmeda) 2 (μ-Oh) 2]Br 2 (2.5 Mol%) 氧化还原催化剂在乙腈中混合.在这个过程的背景下,观测到当从联醇中除去电子时,阻转异构化的能量显着降低.因此,可以将两种对映体转化为热力学有利的[N-苄基辛可尼溴化物.(R)-Binol]加合物.
DOI:10.1021/acs.Orglett.4C00520

专利信息

专利号:US-5554753-A
优先权日:1993-08-25
标 题:Catalytic enantioselective synthesis of α-amino acid derivatives by phase-transfer catalysis
发明人：O'DONNELL MARTIN J; WU SHENGDE; ESIKOVA IRENA; MI AIQIAO
权利人:INDIANA UNIVERSITY FOUNDATION
摘要:Described are improved processes for the enantioselective synthesis of α-amino acids which involve combinations of solvents, highly-mixed and low-temperature reaction conditions, and novel catalysts. Also described are novel catalysts and precursors to α-amino acid derivatives.

专利号:US-2024025839-A1
优先权日:2020-11-11
标 题 :Method of synthesis
发明人：KITCHING MATTHEW OLIVER; WALSH MARK PATRICK
权利人:UNIV DURHAM
摘要:The present invention provides a method of making an enantiomerically enriched tertiary or quaternary ammonium salt, and the use of a non-racemic chiral compound in the synthesis of an enantiomerically enriched tertiary or quaternary ammonium salt. The control of nitrogen-based chirality, achieved via the method of the invention, is useful where a specific tertiary or quaternary ammonium enantiomer is preferred over the other enantiomer, for example where a specific tertiary or quaternary ammonium enantiomer is more effective than the other enantiomer in treating a specific medical condition.

专利号:US-8981152-B2
优先权日:2009-02-25
标题:Microwave induced single step green synthesis of some novel 2-aryl aldehydes and their analogues
发明人：SINHA ARUN KUMAR; SHARMA ABHISHEK; KUMAR RAKESH; SHARMA NAINA
权利人:COUNCIL SCIENT IND RES
摘要:A microwave-induced process for the preparation of 2-aryl and 2,2-diaryl aldehydes and analogs wherein halohydrin formation and subsequent rearrangement to 2-aryl aldehydes from corresponding aryl alkanols occurs without formation of an intermediate epoxide or use of transition metal catalysts or lewis acids/bases.

专利号:US-2012041234-A1
优先权日:2009-02-25
标题:Microwave induced single step green synthesis of some novel 2-aryl aldehydes and their analogues

专利号:US-2014197024-A1
优先权日:2009-02-25
标题:Microwave induced single step green synthesis of some novel 2-aryl aldehydes and their analogues

专利号:WO-2010097811-A1
优先权日:2009-02-25
标题 :Microwave induced single step green synthesis of some novel 2-aryl aldehydes and their analogues