CAS: 58-82-2; L-Arginyl-L-Prolyl-L-Prolylglycyl-L-Phenylalanyl-L-Seryl-L-Prolyl-L-Phenylalanyl-L-Arginine

上下游产品

CAS号74-79-3 L-精氨酸 | CAS号15958-92-6 血管舒缓激肽片段1-8,醋酸盐水合物 | CAS号56-45-1 L-丝氨酸 | CAS号63-91-2 L-苯丙氨酸 | CAS号56-40-6 甘氨酸 | CAS号147-85-3 脯氨酸

📜Z-(No2)Arg-Pro-Pro-Gly-Phe-(Obzl)Ser-Pro-Phe-(No2)Arg-Pnb置于钯 盐酸,氢气体系中,用 溶剂黄146 作为反应溶剂,化学反应 48.0H,以45 Mg的收率获得产物舒缓激肽
参考文献:Jaouadi,Mahmoud; Selve,Claude; Dormoy,Jean-Robert,Bulletin De La Societe Chimique De France,1988,# 5,P. 870-874
标题:Jaouadi,Mahmoud; Selve,Claude; Dormoy,Jean-Robert,Bulletin De La Societe Chimique De France,1988,# 5,P. 870-874

专利信息

专利号:US-7323575-B2
优先权日:2003-04-09
标题:Process for the synthesis of (2S)-indoline-2-carboxylic acid
发明人：SOUVIE JEAN-CLAUDE; LECOUVE JEAN-PIERRE
权利人:SERVIER LAB
摘要:Process for the synthesis of (2S)-indoline-2-carboxylic acid of formula (I): n nApplication in the synthesis of perindopril and its pharmaceutically acceptable salts.

专利号:US-6774259-B2
优先权日:2000-04-11
标 题 :Method for synthesis of n-[(s)]-1-carboxybutyl-(s)-alanine esters and use in synthesis of perindopril
发明人：SOUVIE JEAN-CLAUDE; RENAUD ALAIN
权利人:SERVIER LAB
摘要:A stereoselective process for the industrial synthesis of compounds of formula (I):wherein R represents linear or branched (C1-C6)alkyl, andapplication in the synthesis of perindopril and pharmaceutically acceptable salts thereof.

专利号:US-6818788-B2
优先权日:2000-03-31
标 题:Method for synthesis of n-[(s)-1-carboxybutyl]-(s)-alanine esters and use in synthesis of perindopril
发明人：SOUVIE JEAN-CLAUDE
权利人:SERVIER LAB
摘要:Stereoselective process for the industrial synthesis of compounds of formula (I):wherein R represents linear or branched (C1-C6)alkyl.Application in the synthesis of perindopril and pharmaceutically acceptable salts thereof.

专利号:US-4902817-A
优先权日:1987-09-17
标 题 :Process for the synthesis of alpha n alkylated amino acids and esters thereof, application to the synthesis of carboxyalkyl dipeptides
发明人：VINCENT MICHEL; BALIARDA JEAN; MARCHAND BERNARD; REMOND GEORGES
权利人:ADIR
摘要:Stereoselective process for the industrial synthesis of compounds of formula (I): ##STR1## where R 1 is linear or branched lower alkyl with 1 to 6 carbon atoms, n R 2 is a linear or branched lower alkyl with 1 to 4 carbon atoms, n employing inexpensive starting materials and obtaining optimum yields. n Application to the synthesis of carboxyalkyl dipeptides.

专利号:US-7288661-B2
优先权日:2003-12-10
标 题 :Process for the synthesis of (2S,3aS,7aS)-1-[(S)-alanyl]-octahydro-1H-indole-2-carboxylic acid compounds and application in the synthesis of perindopril
发明人：DUBUFFET THIERRY; LECOUVE JEAN-PIERRE
权利人:SERVIER LAB
摘要:Process for the synthesis of compounds of formula (I): n nwherein R represents a hydrogen atom or a protecting group for the amino function.n n Application in the synthesis of perindopril and pharmaceutically acceptable salts thereof.

专利号:US-12351573-B2
优先权日:2019-05-09
标 题:Compounds for use in synthesis of peptidomimetics
发明人：AL-ABED YOUSEF; CHENG KAI FAN
权利人:FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH
摘要:Synthesis of O-benzotriazole and O-imidazole synthons are described. Uses of synthons in synthesis of azapeptides and other peptidomimetics, azapeptides and other peptidomimetics synthesized from the synthons and uses of azapeptides and other peptidomimetics are also described.