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参考文献:Francois,H. Et Al.,Bulletin De La Societe Chimique De France,1970,# 2,P. 617-624
标题:Francois,H. Et Al.,Bulletin De La Societe Chimique De France,1970,# 2,P. 617-624
专利信息
专利号:US-11149065-B2
优先权日:2017-04-07
标 题:One-bead-two-compound macrocyclic library and methods of preparation and use
发明人:CAI JIANFENG; SHI YAN
权利人:UNIV SOUTH FLORIDA
摘要:A one-bead-two-compound combinatorial synthesis technique provides libraries of macrocyclic peptidomimetic compounds and compositions with use as ligands for the Ephrin type-A receptor 2 (EphA2). The one-bead-two-compound technique and libraries of macrocyclic compounds are useful as research tools in drug discovery and/or to treat or prevent a range of diseases or disorders.
专利号:US-8088923-B2
优先权日:2006-07-07
标题:Cyclic-fused beta-lactones and their synthesis
发明人:ROMO DANIEL; HENRY-RIYAD HUDA; LEE CHANGSUK; NGUYEN HENRY; PUROHIT VIKRAM C; OH SEONGHO
权利人:ROMO DANIEL; HENRY-RIYAD HUDA; LEE CHANGSUK; NGUYEN HENRY; PUROHIT VIKRAM C; OH SEONGHO; TEXAS A & M UNIV SYS
摘要:The present invention provides a concise synthetic method for generating lactam-fused beta-lactones that feature, in some embodiments, a tertiary fused carbinol, quaternary carbons, and a reactive beta-lactone moiety available for further reactions. The present invention further provides compounds synthesized by this method as well as methods of using these compounds as inhibitors of the proteasome and fatty acid synthase.
专利号:US-3636119-A
优先权日:1969-10-20
标题:4-amino-2-(8-cyclohexyloctyl or 7-cyclohexylheptyl)-1-naphthol
发明人:FIESER LOUIS F; LORENZ ROMAN R; ARCHER SYDNEY
权利人:FIESER LOUIS F; ROMAN R LORENZ; SYDNEY ARCHER
摘要:4-AMINO-2-Q-1 NAPHTHOL COMPOUNDS WHICH ARE USEFUL AS INTERMEDIATES IN THE SYNTHESIS OF 2-Q-1,4-NAPHTHOQUINONE COMPOUNDS, WHERE Q IS (7-CYCLOHEXYLHEPTYL OR 8-CYCLOHEXYLOCTYL).