CAS: 33922-73-5; 1-(Prop-2-Enyltrisulfanyl)Propane

上下游产品

Acetyl-aethyldisulfid toluene-4-thiosulfonic acid S-2-propen-1-yl ester

📜Acetyl-Aethyldisulfid,Allyl Thiotosylate置于sodium Methylate体系中,用 四氢呋喃,甲醇 作为反应溶剂,化学反应 0.18H,以95%的收率获得产物丙基烯丙基三硫醚
参考文献:Unsymmetrical Organotrisulfide Formation Via Low-Temperature Disulfanyl Anion Transfer To An Organothiosulfonate
标题:Unsymmetrical Organotrisulfide Formation Via Low-Temperature Disulfanyl Anion Transfer To An Organothiosulfonate
摘要:New Methodology Is Presented For The Formation Of Unsymmetrical Organotrisulfides In A High Yield And Purity,Relatively Free Of Polysulfide Byproducts. The Highlight Of The Method Is The Low-Temperature (-78 Degrees C) Deprotection Of A Disulfanyl Acetate With Sodium Methoxide In Thf To Form A Disulfanyl Anion,Which Reacts Rapidly In Situ With An Organothiosulfonate (S-Aryl Or S-Alkyl) Within 30 Seconds Followed By Quenching. The Discovery Of These New Reaction Conditions Together With The Relative Greenness Of The Chemistry Overall Makes For An Efficient Protocol,From Which A Range Of Organotrisulfides Covering Aliphatic,Aromatic,As Well As Cysteine And Sugar Groups Can Be Accessed In A High Yield And Purity.
DOI:10.1021/acs.Joc.8B03262