CAS: 25561-30-2; N,O-Bis(Trimethylsilyl)Trifluoroacetamide

相似化合物

10416-59-8 105384-38-1

上下游产品

trifluoracetyl chloride sodium hexamethyldisilazane chloro-trimethyl-silane 2,2,2-trifluoroacetamideDimethoxymethane Bis-trimethylsilanyloxy-methane (E)-3-(3-Methoxy-4-trimethylsilanyloxy-phenyl)-acrylic acid

三氟乙酰氯,Sodium Hexamethyldisilazane 反应生成N,O-双(三甲基硅烷基)三氟乙酰胺
参考文献:Lidy,W.; Sundermeyer,W.,Chemische Berichte,1976,Vol. 109,P. 2542-2546
标题:Lidy,W.; Sundermeyer,W.,Chemische Berichte,1976,Vol. 109,P. 2542-2546

专利信息

专利号:US-2009131688-A1
优先权日:2007-11-21
标 题 :Method for the synthesis of 4-benzofuran-carboxylic acid
发明人：BURGOS ALAIN; MARUANI MARTINE; PERRIN FLORENCE; FREIN STEPHANE
权利人:ZACH SYSTEM
摘要:The invention concerns a novel method for synthesis of 4-benzofuran-carboxylic acid or alkyl ester thereof. n This method is characterized in that a reaction for aromatization of a compound of formula (II) is performed for the synthesis of the compound of formula (I), according to the scheme A2 below: n n n n n n n n n n wherein R independently represents hydrogen or a linear or branched C 1 - 15 alkyl group. n With the invention, it is possible to industrially synthesize 4-benzofuran-carboxylic acid or alkyl ester thereof with good yield and very good purity.

专利号:US-2023287032-A1
优先权日:2020-08-14
标 题:Synthesis of fluorinated nucleotides
发明人：CHUNG CHEOL KEUN; LIU ZHIJIAN; MALIGRES PETER E; MAO EDNA; OBLIGACION JENNIFER V; PHILLIPS ERIC M; PIRNOT MICHAEL; POIRIER MARC; SONG ZHIGUO JAKE; WANG TAO
权利人:CHUNG CHEOL KEUN; LIU ZHIJIAN; MALIGRES PETER E; MAO EDNA; OBLIGACION JENNIFER V; PHILLIPS ERIC M; PIRNOT MICHAEL; POIRIER MARC; SONG ZHIGUO JAKE; WANG TAO; MERCK SHARP & DOHME LLC
摘要:The present invention relates to efficient processes useful in the preparation of fluorinated nucleosides, such as (O—{[(2R,3R,4S,5R)-5-(6-amino-9H-purin-9-yl)-4-fluoro-3-hydroxyoxolan-2-yl]methyl}O,O-dihydrogen phosphorothioate, also known as 2′-(S)-fluoro-thio-adenosine monophosphate or 2′-F-thio-AMP. Such fluorinated nucleosides may be useful as a biologically active compound and or as an intermediate for the synthesis of more complex biologically active compounds. The present invention also encompasses intermediates useful in the disclosed synthetic processes and the methods of their preparation.

专利号:WO-9507882-A1
优先权日:1993-09-14
标 题:Synthesis of amido acids from carboxylic acid esters and amino acid salts
发明人：HEINZMAN STEPHEN WAYNE; DUPONT JEFFREY SCOTT
权利人:PROCTER & GAMBLE
摘要:Chemical synthesis of amido acids, and their conversion to amido acid phenyl ester sulfonates for use as bleach activators, starting from carboxylic acid esters and amino acid salts.

专利号:US-9266863-B2
优先权日:2010-03-30
标题 :Process for the synthesis of azacitidine and decitabine
发明人：DE FERRA LORENZO; ZENONI MAURIZIO; TURCHETTA STEFANO; ANIBALDI MAURO; AMMIRATI ETTORE; BRANDI PAOLO; BERARDI GIORGIO
权利人:DE FERRA LORENZO; ZENONI MAURIZIO; TURCHETTA STEFANO; ANIBALDI MAURO; AMMIRATI ETTORE; BRANDI PAOLO; BERARDI GIORGIO; CHEMI SPA
摘要:Described herein is a process for the synthesis of azacitidine or decitabine, comprising the silylation of azacytosine in the presence of N,O-bis-trimethylsilyl-trifluoroacetamide. Such reaction is performed in an organic solvent, preferably aprotic, even more preferably selected from among dichloromethane, dichloroethane and/or acetonitrile. According to a further aspect of the process, 2 to 3 moles of N,O-bis-trimethylsilyl-trifluoroacetamide are used per mole of azacytosine, preferably from 2.2 to 2.5.

专利号:US-5681971-A
优先权日:1994-12-12
标题 :Synthesis of fatty N-alkyl amides
发明人：SCHEIBEL JEFFREY JOHN; SHUMATE ROBERT EDWARD
权利人:PROCTER & GAMBLE
摘要:Fatty N-alkyl amides are synthesized directly from glycerides (preferably triglycerides) and amines in the absence of a catalyst, and preferably without a solvent. The method provides for products suitable for use without further purification, preferably after separating the glycerol and amide products. The disclosed method is also useful for the synthesis of glycerol from glycerides and ammonia and/or primary amines.

专利号:US-5534642-A
优先权日:1993-09-14
标题 :Synthesis of amido acids from carboxylic acids and lactams
发明人：HEINZMAN STEPHEN W; DUPONT JEFFREY S; TETTENHORST WILLIAM C
权利人:PROCTER & GAMBLE
摘要:Chemical synthesis of amido acids, and their conversion to amido acid phenyl ester sulfates for use as bleach activators, starting from carboxylic acids and lactams.