专利号:US-2009018343-A1 优先权日:2005-03-16 标题 :Fluorous Oxazolidinone Chiral Auxiliary Compounds and Methods of Manufacture 发明人:HULTIN PHILIP GREGORY; HEIN JASON ELLIS 权利人:UNIV MANITOBA 摘要:The present invention relates generally to perfluoroalkyl chiral auxiliary compounds and methods of manufacture. These compounds have the functionality to effectively support the synthesis of chiral compounds in single reactions, high-throughput parallel reactions, or combinatorial reactions The invention relates to two oxazolidinone chiral auxiliaries (1) and (2): wherein R f is a perfluoroalkyl group having the general formula (CH 2 ) x —C y F 2y+1 where x=1-5 and y=4-10 and wherein B is an unfunctionalized aryl, alkyl or arylalkyl group in a preferred embodiment, x=2 and y=6 and B is derived from unfunctionalized amino acids The amino acids may be from either the D- or L-series, and are preferably enantiomerically pure or in very high enantiomeric excess in either configuration.
专利号:US-2007100184-A1 优先权日:2005-10-27 标题 :Alkylation of aromatic compounds 发明人:HARMER MARK A; JUNK CHRISTOPHER P; VICKERY JEMMA 权利人:HARMER MARK A; JUNK CHRISTOPHER P; VICKERY JEMMA 摘要:The present invention relates to the synthesis of alkylated aromatic compounds using ionic liquids as the solvent. Alkylated aromatic compounds are synthesized by reacting an aromatic compound with a monoolefin in the presence of an acid catalyst.
专利号:US-4791223-A 优先权日:1986-12-22 标题:Process for the preparation of 1,1,2,2-tetrahydroperfluoroalkanols and their esters 发明人:LANTZ ANDRE; MICHAUD PASCAL 权利人:ATOCHEM 摘要:The invention relates to the synthesis of 1,1,2,2-tetrahydroperfluoroalkanols and their esters by oxidizing a 2-(perfluoroalkyl)ethyl iodide using hydrogen peroxide in a carboxylic acid or carboxylic acid ester in the presence of sulphuric acid. n In the process according to the invention, from 1 to 30 moles of sulphuric acid, from 1 to 50 moles of carboxylic acid or of an ester of such an acid, and from 3 to 20 moles of hydrogen peroxide per mole of 2-perfluoralkyl)ethyl iodide are used.
专利号:US-4800234-A 优先权日:1986-12-22 标 题 :Synthesis of 1,1,2,2-tetrahydroperfluoroalkanols and their esters 发明人:LANTZ ANDRE; MICHAUD PASCAL 权利人:ATOCHEM 摘要:The invention relates to the preparation of 1,1,2,2-tetrahydroperfluoroalkanols and their esters. n A 2-(perfluoroalkyl)ethyl iodide is oxidized using peroxomonosulphuric acid or peroxodisulphuric acid in a carboxylic acid or carboxylic acid ester.
专利号:US-6656446-B1 优先权日:1999-04-29 标题:Synthesis of hydrogen peroxide 发明人:BECKMAN ERIC J; HANCU DAN 权利人:UNIV PITTSBURGH 摘要:A method for synthesizing hydrogen peroxide comprises the step of: mixing an analog of a secondary alcohol that is soluble with carbon dioxide with a free radical initiator and oxygen in carbon dioxide to generate hydrogen peroxide. Another method of synthesizing hydrogen peroxide comprises the step of: mixing hydrogen, oxygen and a CO 2 -philic catalyst in carbon dioxide phase. The CO 2 -philic catalyst is soluble or miscible in carbon dioxide and is suitable to catalyze the reaction of hydrogen and oxygen to produce hydrogen peroxide. The method also comprises the step of reacting the hydrogen and oxygen to produce hydrogen peroxide.
专利号:WO-03070714-A1 优先权日:2002-02-20 标题 :Fluorous acetylation 发明人:READ ROGER 权利人:UNISEARCH LTD; READ ROGER 摘要:The present invention relates to a method for the synthesis of highly fluorinated compounds and to novel highly fluorinated compounds. In particular, the present invention relates to the synthesis of highly fluorinated acetals and ketals and their thio analogues and to novel highly fluorinated acetals and ketals and their thio analogues.