CAS: 18523-47-2; 3-Azidopropanoic Acid

相似化合物

54447-68-6 79583-98-5 1620171-64-3

上下游产品

acrylic acid β-Propiolactone 3-Bromopropionic acid azido-b-alanine methyl ester 74H74N10O18SC74H74N10O18S

📜丙烯酸置于叠氮基三甲基硅烷,Amberlite Ira900F体系中,化学反应 2.0H,以73%的收率获得3-叠氮丙酸
参考文献:Amberlite Ira900F 作为固体氟化物源,用于在无溶剂条件下进行各种有机转化
标题:Amberlite Ira900F 作为固体氟化物源,用于在无溶剂条件下进行各种有机转化
摘要:我们已经报道,Amberlite Ira900F (Amb-F) 是一种有效的无金属催化剂,用于在无溶剂条件下激活 Si-N 和 Si-O 键和各种有机转化中的温和碱,例如添加将 Tmsn3 转化为 (E)-2-芳基-1-氰基-1-硝基乙烯,腈,α,β-不饱和酸及其酯,以及将二甲基甲硅烷基乙烯酮缩醛和硝基乙酸乙酯加成到 β-硝基苯乙烯.(© Wiley-Vch Verlag Gmbh & Co. Kgaa,69451 Weinheim,Germany,2008)
Doi:10.1002/ejoc.200800142

专利信息

专利号:US-2023407293-A1
优先权日:2021-10-27
标 题:Dna-encoded and affinity-tagged masked-warhead compounds and use thereof in assembling libraries of small molecules enabled for late-stage purification and multiplexed screening of covalent ligands
发明人：MAIANTI JUAN PABLO
权利人:MAIANTI JUAN PABLO
摘要:The present disclosure relates to DNA-encoded and affinity-tagged masked warhead installation compounds and use thereof in the synthesis of electrophilic warhead DNA-Encoded Libraries (eDEL), including substituted and unsubstituted acrylamide warheads, which can be purified from unreacted library intermediates and byproducts.

专利号:US-8076496-B2
优先权日:2000-03-16
标题:Chemoselective ligation
发明人：SAXON ELIANA; BERTOZZI CAROLYN RUTH
权利人:SAXON ELIANA; BERTOZZI CAROLYN RUTH; UNIV CALIFORNIA
摘要:The present invention features a chemoselective ligation reaction that can be carried out under physiological conditions. In general, the invention involves condensation of a specifically engineered phosphine, which can provide for formation of an amide bond between the two reactive partners resulting in a final product comprising a phosphine moiety, or which can be engineered to comprise a cleavable linker so that a substituent of the phosphine is transferred to the azide, releasing an oxidized phosphine byproduct and producing a native amide bond in the final product. The selectivity of the reaction and its compatibility with aqueous environments provides for its application in vivo (e.g., on the cell surface or intracellularly) and in vitro (e.g., synthesis of peptides and other polymers, production of modified (e.g., labeled) amino acids).

专利号:US-2024109924-A1
优先权日:2021-01-29
标 题 :Ip4-4,6 substituted derivative compounds
发明人：PÉREZ FERRER MARÃ?A DEL MAR; FERRER REYNÉS MIQUEL DAVID; BASSISSI MOHAMAD FIRAS; SALCEDO ROCA CAROLINA; SERRA COMAS CARME; CATENA RUIZ JUAN LORENZO; LLEBARIA SOLDEVILA AMADEU; ORTEGA CASTRO JOAQUÃ?N; PERELLÓ BESTARD JOAN
权利人:SANIFIT THERAPEUTICS S A
摘要:The present invention provides IP4-4,6 substituted derivatives, their methods of synthesis and their uses. In some aspects, the IP4-4,6 derivative is a compound of formula I wherein R1, R3, R7, and R11 are OPO32−, and R5 and R9 are selected from the group consisting of —O(Alkyl)nX, —O(Alkyl)yCy(Alkyl2)y-Z, —O(Alkyl)yA(Alkyl)y-Z′, and their thiophosphate analogs. Also provided are methods, pharmaceutical compositions and formulations, methods of use, articles of manufacture, and kits for the treatment of diseases and conditions such as pathological crystallization-related diseases and conditions.

专利号:US-12188086-B2
优先权日:2018-03-15
标 题:Nucleotide analogues and use thereof for nucleic acid sequencing and analysis preliminary class
发明人：JU JINGYUE; LI XIAOXU; KUMAR SHIV; CHEN XIN; RUSSO JAMES J; CHIEN MINCHEN; JOCKUSCH STEFFEN; TAO CHUANJUAN; WANG XUANTING; KALACHIKOV SERGEY; Morozova Irina; SHI SHUNDI
权利人:UNIV COLUMBIA
摘要:The invention provides various orthogonal nucleotide analogues and methods for using combinations of said various orthogonal nucleotide analogues for sequencing by synthesis.

专利号:CN-116640123-A
优先权日:2022-02-15
标 题:Bifunctional molecule compound for inducing degradation of HK2 protein and synthesis and application thereof

专利号:CN-115433356-A
优先权日:2022-03-11
标 题:A kind of PEG-modified fluorinated Cy7 micelles and its synthesis method and application