CAS: 1190-22-3; 1,3-Dichlorobutane

该化合物是一种有机化合物,被归类为氯化碳氢化合物,具有四碳直链结构,与第一和第二碳原子相连的两个氯原子,该化合物一般是室内温度无色液体,具有独特的气味,其分子式为C4H8Cl2, 其沸点相对较低,导致其挥发性. 1,3-二氯丁烷在有机溶剂中可溶解,但由于其疏水性,其溶解性有限.该物质主要用于有机合成,并作为各种化学品的生产中间体.氯原子在其结构中的存在有助于其再活性,使其在替代反应中有用.然而,重要的是要谨慎地处理这一化合物,因为氯化碳氢化合物可能对环境和健康造成危害,包括潜在的毒性和致癌性.在实验室或工业环境中与1,1,3-二氯丁烷合作时,应当采取适当的安全措施.

结构式图片

相似化合物

626-92-6 2346-81-8 30122-12-4

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

formaldehyd propene s-butyl chloride 1.3-butanediol 4-chloro-valeronitrile 2-methylglutaronitrile 1.3-butanediol methylcyclopropane

合成工艺路线路线简述

    1,3-丁二醇置于氯化亚砜,2,3-二甲基苯胺体系中,化学反应生成1,3-二氯正丁烷
    参考文献:Shishido; Nozaki,Journal Of The American Chemical Society,1947,Vol. 69,P. 963
    标题:Shishido; Nozaki,Journal Of The American Chemical Society,1947,Vol. 69,P. 963

    海关参考信息

    专利信息


    专利号:US-5144073-A
    优先权日:1988-08-31
    标 题 :Process for preparation of dipeptides
    发明人:HUBBS JOHN C
    权利人:HUBBS JOHN C
    摘要:Disclosed is a process for synthesis of a dipeptide such as N-acetyl-L- alpha -aspartyl-L-phenylalanine methyl ester wherein one amino acid serves as a chiral template which allows for synthesis of a second amino acid residue to form said dipeptide. The process involves several novel steps such as a nucleophile addition step. In addition, several novel intermediates are described.

    专利号:US-2023111600-A1
    优先权日:2019-12-17
    标题 :Polymeric fatty acid compounds for the treatment of fibrous amino acid-based substrates, especially hair
    发明人:WAGNER ROLAND; STREICHER KATHARINA; ROHMANN LAURA; WENSKE CHRISTIAN; HAVELI SHRUTISAGAR DATTATRAYA
    权利人:MOMENTIVE PERFORMANCE MAT GMBH
    摘要:The present invention is directed at mono-, di- or polyquaternary ammonium compounds of the formula (I) wherein x is 1 to 50, and F can be the same or different and is represented by the general formula (II) wherein at least one of the optionally substituted and optionally functional-group-containing hydrocarbon radicals R 1 , R 2 , R 3 , R 4 or R 5 contains at least one estolide moiety comprising two or more ester or amide moieties. The invention also relates to a process for the synthesis of such compounds, the use of the compounds in cosmetic formulations for skin and hair care, cosmetic compositions for the treatment of fibers, and compositions containing one or more of the compounds for the treatment of hair.

    专利号:US-2004110228-A1
    优先权日:2002-04-01
    标 题:Combinatorial organic synthesis of unique biologically active compounds
    发明人:MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
    摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.

    专利号:US-5783577-A
    优先权日:1995-09-15
    标题 :Synthesis of quinazolinone libraries and derivatives thereof
    发明人:HOUGHTEN RICHARD A; OSTRESH JOHN M
    权利人:TREGA BIOSCIENCES INC
    摘要:The present invention provides synthetic combinatorial libraries of organic compounds based on the quinazolinone ring.

    专利号:WO-9710221-A1
    优先权日:1995-09-15
    标 题:Synthesis of quinazolinone libraries
    发明人:HOUGHTEN RICHARD A; OSTRESH JOHN M
    权利人:TORREY PINES INST
    摘要:The present invention provides synthetic combinatorial libraries of organic compounds based on the quinazolinone ring.

    专利号:US-6664282-B2
    优先权日:1999-09-17
    标 题:Synthesis of [3,5,7]-1H-imidazo [1,5-a]imidazol-2 (3H)- one compounds
    发明人:ELABDELLAOUI HASSAN M; OSTRESH JOHN M; HOUGHTEN RICHARD A
    权利人:TORREY PINES INST
    摘要:Individual substituted [3,5,7]-1H-imidazo[1,5-a]imidazol-2(3H)-one compounds and their pharmaceutically-acceptable salts are disclosed, as are libraries of such compounds. Methods of preparing and using the libraries of compounds as well as individual compounds of the libraries are also disclosed.
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    合成参考文献


    摘要:Kantchev, E. A. B.; Organ, M. G., Science of Synthesis, (2009) 48, 38.
    摘要:Adak, L.; Sahoo, S.; Aoki, S.; Kawanaka, Y.; Nakamura, M., Science of Synthesis: Base-Metal Catalysis, (2023) 2, 391.
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