CAS: 1004-75-7; 2,5,6-Triaminopyrimidin-4(3H)-One

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📜2,5,6-Triaminopyrimidin-4(3H)-One Dihydrochloride置于sodium Sulfite体系中,用 水 用作溶剂,化学反应 0.5H,反应生成6-羟基-2,4,5-三氨基嘧啶
参考文献:7-甲基-6-吲哚蝶呤和7-甲基-6-吲哚喹喔啉的合成
标题:7-甲基-6-吲哚蝶呤和7-甲基-6-吲哚喹喔啉的合成
摘要:摘要 吲哚蝶呤和吲哚喹喔啉是分别连接吲哚的 C-2 和蝶呤的 C-6(显示生物活性的重要位置)和喹喔啉的两个重要且不同的二杂环,它们的首次合成基于两个经典反应.将酮甲基引入蝶呤和喹喔啉的 6 位,然后进行 Fischer 吲哚合成,产生这些目标二杂环.这些吲哚取代的二杂环会显着增加蝶呤-5-N和喹恶唑啉-2-N上的电子密度,这可能会改变蝶呤和喹喔啉的氧化还原性质,而且吸电子蝶呤或喹恶唑啉应该使吲哚nh更酸.图形概要
Doi:10.1080/00397911.2016.1215467

专利信息

专利号:US-8809553-B2
优先权日:2010-06-15
标题:Process for the preparation of pteridine derivatives
发明人：ATTOLINO EMANUELE; MICHIELETTI MARIO; ROSSI DAVIDE; ALLEGRINI PIETRO
权利人:ATTOLINO EMANUELE; MICHIELETTI MARIO; ROSSI DAVIDE; ALLEGRINI PIETRO; DIPHARMA FRANCIS SRL
摘要:The application discloses a process for the preparation of 5-deoxy-L-arabinose of formula (VI); comprising the conversion of a compound of formula (XII); wherein n is 0, 1 or 2; which can be used as intermediate for the synthesis of sapropterin.

专利号:WO-2011000481-A1
优先权日:2009-07-02
标 题 :Synthesis of pyrazine derivates
发明人：IGNATYEV NIKOLAI MYKOLA; SHEREMETEV ALEXEI B; ALEXANDROVA NATALIA S
权利人:MERCK PATENT GMBH; IGNATYEV NIKOLAI MYKOLA; SHEREMETEV ALEXEI B; ALEXANDROVA NATALIA S
摘要:The present invention relates to a method for producing pyrazine derivates, wherein the reaction medium comprises at least one ionic liquid, and to the use of ionic liquids for producing pyrazine derivates.

专利号:US-2012184724-A1
优先权日:2009-09-22
标 题 :Protected monomers and methods of deprotection for rna synthesis
发明人：SIERZCHALA AGNIESZKA B; SMART BRIAN PHILLIP; DELLINGER DOUGLAS J; DELLINGER GERALDINE; MYERSON JOEL; TIMAR ZOLTAN
权利人:SIERZCHALA AGNIESZKA B; SMART BRIAN PHILLIP; DELLINGER DOUGLAS J; DELLINGER GERALDINE; MYERSON JOEL; TIMAR ZOLTAN; AGILENT TECHNOLOGIES INC
摘要:A nucleoside monomer that is protected by a thionocarbamate protecting group and contains one or more 2 H, 13 C, or 15 N isotopes in the ribose and/or base part is provided, as well as a method for making a polynucleotide that uses the same. Also provided is a polynucleotide synthesis method that employs a diamine to deprotect a protected polynucleotide.

专利号:US-9266889-B2
优先权日:2011-03-25
标题:Composition, synthesis, and use of new substituted pyran and pterin compounds
发明人：BASU PARTHA; PIMKOV IGOR
权利人:UNIV HOLY GHOST DUQUESNE
摘要:The present invention relates to substituted pterin compounds, their synthesis and use. In particular, the present invention relates to a new precursor compound and its analogs for synthesizing a new substituted pterin compound and its analogs. These new compounds are particularly suitable for treating molybdenum cofactor deficiency.

专利号:US-2007243147-A1
优先权日:2004-07-24
标 题:Skin and/or Hair Composition Containing Compounds for Increasing The Tanning of Skin
发明人：WOLBER RAINER; TOM DIECK KAREN; SCHERNER CATHRIN; SCHLENZ KATHRIN; KRUSE INGE
权利人:BEIERSDORF AG
摘要:The invention relates to agents that are to be applied to the skin or hair and contain compounds for intensifying tanning of the skin and increasing melanin synthesis in skin or hair. The invention particularly relates to cosmetic or dermatological preparations. Using said preparations results in inducing and intensifying the tanning mechanisms of the skin, intensifying the hair color, and thus also increasing intrinsic protection of the skin or hair.

专利号:US-9943809-B2
优先权日:2014-02-27
标题 :Solvent resistant thin film composite membrane and its preparation
发明人：DOM ELKE; HERMANS SANNE; KOECKELBERGHS GUY; VANKELECOM IVO
权利人:KATHOLIEKE UNIV LEUVEN KU LEUVEN RESEARCH & DEVELOPMENT; UNIV LEUVEN KATH
摘要:The present invention relates to improved methods for synthesis of thin film composite membranes by interfacial polymerization. More in particular, the method of the present invention comprises the impregnation of an ultrafiltration porous support membrane with an aqueous solution containing a polyfunctional nucleophilic monomer, and contacting the impregnated support membrane with a second largely water-immiscible solvent containing a polyfunctional epoxide monomer.