CAS: 98-56-6; 4-Chlorobenzotrifluoride

上下游产品

4-chlorotrichloromethylbenzene 4-trifluoromethylphenylamine brom°Chlorobenzene Bromotrifluoromethane 1-ethoxy-4-(trifluoromethyl)benzene methyl 4-(trifluoromethyl)phenyl ether 4-hydroxy-benzoic acid 4,4'-Dichlorobenzophenone

4-氯三氯甲苯置于氢氟酸体系中,90.0 °C,1.5 Mpa 条件下,反应 2.0H,反应生成 对氯三氟甲苯
参考文献:一种芳香族含氟化合物的连续合成方法及其合成设备
标题:一种芳香族含氟化合物的连续合成方法及其合成设备
摘要:本发明公开了一种芳香族含氟化合物的连续合成方法及其合成设备,包括以下步骤:芳香族氯化物自氟化反应塔的顶部进入,无水氟化氢液体自底部进入,在氟化反应塔内进行逆向氟化反应;尾气依次经过冷凝器和酸雾捕集器后,与无水氟化氢液体混合后共同自顶部进入;氟化反应塔的底部得到芳香族含氟化合物.连续合成设备包括氟化反应塔,氟化反应塔的氯化物进口连通有氯化物储罐;氟化反应塔的下部和中部分别设有氟化氢进口;氟化反应塔尾气出口依次连通有冷凝器,酸雾捕集器和混合器;混合器的出口连通所述氯化物进口;氟化反应塔的底部设有芳香族含氟化合物出口.本发明不仅实现了连续反应,而且工艺流程短,生产安全性高,产品质量稳定.

专利信息

专利号:US-5512701-A
优先权日:1995-06-07
标题:Process for the synthesis of vinyl sulfenic acid derivatives
发明人：HOARD DAVID W; LUKE WAYNE D
权利人:LILLY CO ELI
摘要:The present invention is directed to a new process for the synthesis of vinyl sulfenic acid derivatives. These compounds are useful for the synthesis of benzo[b]thiophenes, in particular 2-aryl-benzo[b]thiophenes.

专利号:EP-0058173-B1
优先权日:1980-08-26
标 题:Process for the synthesis of aryloxy derivatives
摘要:Process for the synthesis of compounds of formula I (FORMULA) wherein O, is a substituted or unsubstituted aryl or heteroaryl group and U and V may be chosen from a range of substituents including hydrogen, halogen, alkyl and alkoxy; the process comprising reacting a sulfate ester of formula II, wherein Q is a cation, with a compound of formula III, wherein L is a leaving group (FORMULA) and hydrolysing the sulfate ester formed. Preferably the sulfate ester of formula II is prepared by the oxidation of a phenol of formula IV with a persulfate.

专利号:US-6372945-B1
优先权日:1995-06-07
标 题 :Process for the synthesis of vinyl sulfoxides
发明人：AIKINS JAMES A; MILLER RANDAL SCOT; ZHANG TONY Y
权利人:LILLY CO ELI
摘要:The present invention is directed to a new process for the synthesis of vinyl sulfoxides, in particular diarylvinyl sulfoxides

专利号:US-6846957-B2
优先权日:2002-11-22
标题 :Synthesis of 3-aminomethyl-1-propanol, a fluoxetine precursor
发明人：ZELENIN ALEXANDER
权利人:UNIV TEXAS
摘要:The present invention concerns a method of synthesizing fluoxetine hydrochloride. The method includes the synthesis of 3-methylamino-1-phenyl-1-propanol by reduction of 1-phenyl-3-methylamino-2-propen-1-one with sodium borohydride and acetic acid.

专利号:US-5606076-A
优先权日:1995-06-07
标 题 :Process for the synthesis of benzo[b]thiophenes
发明人：AIKINS JAMES A; ZHANG TONY Y
权利人:LILLY CO ELI
摘要:The present invention is directed to a process for the synthesis of 2-arylbenzo[b]thiophenes.

专利号:US-5569772-A
优先权日:1995-06-07
标 题:Process for the synthesis of benzo[b]thiophenes
发明人：HOARD DAVID W; LUKE WAYNE D
权利人:LILLY CO ELI
摘要:The present invention is directed to a new process for the synthesis of 2-aryl benzo[b]thiophenes, and to novel intermediates therefor.