CAS: 94444-58-3; 2-Chloro-4-Fluorobenzotrifluoride

该化合物是一种芳香化合物,其特点是存在一个苯环,代之以氯原子,氟原子和三氟甲基组;该化合物显示出一个分子结构,有助于其独特的化学特性,包括其反应性和极度;多种电阴性卤原子(氯和氟)的存在,增强了其电子带生特性,这可能影响其化学反应行为,特别是电光替代;已知三氟甲基组具有显著的亲脂性和稳定性,使该化合物在各种应用中,包括制药和农用化学品中潜在有用;此外,该化合物的物理特性,如沸点和溶性,受到其卤素亚体的影响,可能影响其与其他物质的相互作用;

英文名称2-Chloro-4-Fluorobenzotrifluoride
中文名称2-氯-4-氟三氟甲苯
IUPAC名称2-chloro-4-fluoro-1-(trifluoromethyl)benzene
其它别名2-氯-4-氟三氟甲基苯; 2-Chloro-4-Fluorobenzotrifluor
CAS编号94444-58-3
MFCD编号:MFCD03412197
分子式:C7H3ClF4
分子量:198.55
产品CID: 1995034
产品分类有机原料→分子砌块→芳环类化合物→苯类化合物

相似结构搜索
InChIKey: UHHZGIHGBLCIJM-UHFFFAOYSA-N
InChI=1S/C7H3ClF4/c8-6-3-4(9)1-2-5(6)7(10,11)12/h1-3H…
计算化学: 氢键受体数0.0氢键供体数0.0可旋转键数0.0

MSDS等安全信息

GHS符号GHS07
警示词Warning
危险描述H302-H315-H319-H335
防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
危险品标志Xi
风险等级Irritant
安全声明26-36/37/39
危险类别码36/37/38

上下游产品

CAS号151504-80-2 2-氯-4-硝基三氟甲苯 | CAS号37900-81-5 3-氯-4-三氟甲基苯酚

合成工艺路线路线简述

151504-80-2 = 94444-58-3
反应条件:1.1 Reagents: Tetraphenylphosphonium Bromide,Potassium Fluoride Solvents: Dimethyl Sulfoxide
标题:Selective Fluorodenitration Of Chloronitroaromatics
作者:Beaumont,Andrew J.; Clark,James H.; Boechat,Nubia A.
参考文献:Journal Of Fluorine Chemistry 日期:1993 卷标:63(1-2) 页码:25-30]

= 94444-58-3 [标题:Reaction Conditions
标题:(Trifluoromethyl)Benzene Derivatives
参考文献:France]

654-99-9 = 94444-58-3
反应条件:1.1 Reagents: Trichloroisocyanuric Acid,Bromine Solvents: Carbon Tetrachloride; 18 H,100 °C
标题:Process For The Preparation Of Organic Halides
参考文献:World Intellectual Property Organization]

= 94444-58-3 [标题:Reaction Conditions
标题:Method For Producing Fluorinated Aromatic Compound
参考文献:World Intellectual Property Organization

2-氯-4-硝基三氟甲苯置于potassium Fluoride,四苯基溴化膦体系中,用二甲基亚砜作为反应溶剂,化学反应 5.0H,以48%的收率获得产物2-氯-4-氟三氟甲苯
参考文献:Selective Fluorodenitration Of Chloronitroaromatics
标题:Selective Fluorodenitration Of Chloronitroaromatics
摘要:Nucleophilic Fluorination Of Chloronitrobenzenes Shows A Strong Bias For Fluorodenitration Rather Than Halogen Exchange.
DOI:10.1016/s0022-1139(00)80394-2

海关参考信息

2902300000-甲苯
2903919090-氯苯
2903399090-其他无环烃卤化衍生物
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:WO-9724318-A1
优先权日:1995-12-28
标题:Method for synthesis of an aromatic derivative substituted by a halogen atom other than fluorine and by a cyano group

专利号:EP-0882012-B1
优先权日:1995-12-28
标题 :Method for synthesis of an aromatic derivative substituted by a halogen atom other than fluorine and by a cyano group

专利号:EP-0882012-A1
优先权日:1995-12-28
标题:Method for synthesis of an aromatic derivative substituted by a halogen atom other than fluorine and by a cyano group

专利号:EP-1853548-A1
优先权日:2005-02-22
标题 :Process for the preparation of benzoic acid derivatives via a new intermediate of synthesis

专利号:WO-2006090210-A1
优先权日:2005-02-22
标题:Process for the preparation of benzoic acid derivatives via a new intermediate of synthesis