2-溴-6-硝基甲苯置于硫酸,三氯化铁,甲烷,一水合肼,Sodium Nitrite体系中,用 甲醇 作为反应溶剂,化学反应 12.0H,反应生成 3-溴-2-甲基苯酚 参考文献:First Total Synthesis Of The Neuronal Cell Protecting Carbazole Alkaloid Carbazomadurin A By Sequential Transition Metal-Catalyzed Reactions 标题:First Total Synthesis Of The Neuronal Cell Protecting Carbazole Alkaloid Carbazomadurin A By Sequential Transition Metal-Catalyzed Reactions 摘要:从异香兰酸出发,经过九个步骤合成了保护神经细胞的高氧咔唑生物碱咔唑马杜林 A,总收率为 11%. DOI:10.1039/b301979A
专利号:WO-0031134-A9 优先权日:1998-11-20 标题:Regulation of hair follicle morphogenesis based on beta-catenin 发明人:GAT URI; DASGUPTA RAMANUJ; DEGENSTEIN LINDA; FUCHS ELAINE 权利人:ARCH DEV CORP; GAT URI; DASGUPTA RAMANUJ; DEGENSTEIN LINDA; FUCHS ELAINE 摘要:The present invention provides a method for inducing hair growth by providing beta-catenin activity to a skin cell. This may be achieved by providing a beta-catenin polypeptide, providing a beta-catenin agonist, providing a polynucleotide encoding a beta-catenin polypeptide, enhancing the de novo synthesis of beta-catenin, increasing the stability or decreasing the degradation of beta-catenin polypeptides.
专利号:US-10815255-B2 优先权日:2017-01-06 标题:Synthesis of benzyloxyphenoxy phenol ligands 发明人:FALER CATHERINE A; HARLAN C JEFF 权利人:UNIVATION TECH LLC 摘要:Synthetic methods for the preparation of ligands and metal-ligand complexes are disclosed.
专利号:US-2009093521-A1 优先权日:2005-06-14 标 题 :2, 5-Bis-Diamine [1,4] Benzoquinone-Derivatives 发明人:BOLOGNESI MARIA LAURA; BANZI RITA; MINARINI ANNA; MELCHIORRE CARLO 权利人:BOLOGNESI MARIA LAURA; BANZI RITA; MINARINI ANNA; MELCHIORRE CARLO 摘要:Synthesis of 2,5-bis-diamine-[1,4]benzoquinonic derivatives having the general formula (I), products and intermediates of said synthesis; the synthesis involves the use of p-benzoquinones having the general formula (IX) and diamines having the general formula (XI).
专利号:US-2019352314-A1 优先权日:2017-01-06 标题:Synthesis of benzyloxyphenoxy phenol ligands
专利号:US-9889182-B2 优先权日:2009-09-15 标 题 :Assisted enzyme replacement therapy 发明人:ESKO JEFFREY D; TOR YITZHAK 权利人:ESKO JEFFREY D; TOR YITZHAK; UNIV CALIFORNIA 摘要:Reagents and methods useful for the synthesis of conjugates comprising guanidinylated cyclic acetals are provided. Also provided are methods for increasing the cellular uptake of various therapeutic compounds and treatment modalities using these conjugates.
专利号:WO-2018129235-A1 优先权日:2017-01-06 标 题 :Synthesis of benzyloxyphenoxy phenol ligands
参考文献:10.1186/2191-0855-3-14 摘要:Chanwun T, Muhamad N, Chirapongsatonkul N, Churngchow N. Hevea brasiliensis cell suspension peroxidase: purification, characterization and application for dye decolorization. AMB Express. 2013 Feb 12;3(1):14.