CAS: 627-11-2; 2-Chloroethyl Carbonochloridate

相似化合物

17341-93-4 50893-53-3 628-11-5

上下游产品

CAS号32315-10-9 三光气 | CAS号107-07-3 2-氯乙醇 | CAS号75-44-5 光气 | CAS号75-21-8 环氧乙烷 | CAS号96-49-1 碳酸乙烯酯 | CAS号10288-17-2 2-chloroethyl n... | CAS号124-05-0 亚乙基二氯甲酸酯 | CAS号503-38-8 氯甲酸三氯甲酯 | CAS号110-86-1 吡啶 | CAS号5130-24-5 氯甲酸乙烯酯 | CAS号4926-55-0 N-(2-硝基苯基)乙醇胺 | CAS号4620-70-6 N-叔丁基乙醇胺 | CAS号20485-86-3 2-chloroethyl N... | CAS号107-21-1 乙二醇 | CAS号25216-25-5 Carbamic acid,1... | CAS号25217-18-9 2-chloroethyl N... | CAS号2508-01-2 3-(2-氯乙基)-2-噁唑烷酮 | CAS号25203-37-6 Carbanilic acid... | CAS号107-06-2 1,2-二氯乙烷

碳酸乙烯酯置于五氯化磷体系中,化学反应生成 氯甲酸氯乙酯
参考文献:Gross,H. Et Al.,Chemische Berichte,1961,Vol. 94,P. 544-550
标题:Gross,H. Et Al.,Chemische Berichte,1961,Vol. 94,P. 544-550

专利信息

专利号:US-8269001-B2
优先权日:2005-10-05
标题 :Process for the synthesis of HMG-CoA reductase inhibitors
发明人：CASAR ZDENKO
权利人:CASAR ZDENKO; LEK PHARMACEUTICALS
摘要:A novel synthesis of statins uses Wittig reaction of a heterocyclic core of statin with a lactonized side chain already possessing needed stereochemistry. Any separation of diastereoisomers is performed early in the course of synthesis.

专利号:US-6306179-B1
优先权日:1997-10-22
标题:Method for the synthesis of 2-hydroxyalkyl-para-phenylenediamines, new 2-hydroxyalkyl-para-phenylenediamines, their use for oxidation dyeing, dyeing compositions and methods of dyeing
发明人：GENET ALAIN; LAGRANGE ALAIN
权利人:OREAL
摘要:The present invention relates to a new method for the synthesis of 2-hydroxyalkyl-para-phenylenediamines which are substituted or unsubstituted at the 5-position of the benzene ring, new 2-hydroxyalkyl-para-phenylenediamines which are substituted or unsubstituted at the 5-position of the benzene ring, their use for the oxidation dyeing of keratinous fibers, the dyeing compositions containing them, as well as the methods of dyeing using them.

专利号:EP-2465936-A1
优先权日:2010-12-20
标题 :Enzymatic synthesis of statins and intermediates thereof
权利人:LEK PHARMACEUTICALS
摘要:The present invention discloses a process for preparing an active pharmaceutical ingredient (API) or intermediates thereof, notably particular step in the synthesis of an intermdiate useful for example in the preparation of statins, by using an enzyme capable of catalyzing oxidation or dehydrogenation. The invention further provides an expression system effectively translating said enzyme. In addition, the invention relates to a specific use of such enzyme for preparing API or intermediate thereof, and in particular for preparing statin or interemediate thereof.

专利号:US-8471045-B2
优先权日:2007-04-03
标题 :Synthesis of statins
发明人：CASAR ZDENKO; MESAR TOMAZ; KOPITAR GREGOR; MRAK PETER; OSLAJ MATEJ
权利人:CASAR ZDENKO; MESAR TOMAZ; KOPITAR GREGOR; MRAK PETER; OSLAJ MATEJ; LEK PHARMACEUTICALS
摘要:The process for the synthesis of statins featuring the use of an early intermediate (4R,6S)-6-(dialkoxymethyl)tetrahydro-2H-pyran-2,4-diol which already possesses the desired stereochemistry corresponding to the final statin.

专利号:WO-2008101514-A1
优先权日:2007-02-22
标 题:Nucleoside analogues for the treatment of viral infections and methods for preparing them
发明人：BIONDI FABIO
权利人:NANODREAM S R L UNIPERSONALE; BIONDI FABIO
摘要:New pyrrolidine derivatives are disclosed having formula (I) wherein R1 and R2 are protecting groups independently selected from R-C(=O), wherein R is straight or branched C1-C15 alkyl, C6-C15 aryl, substituted C5-C15 aryl including from (1) to (5) heteroatoms and R3 is a nucleobase selected from thymine I, cytosine II, adenine III, guanine IV, uracile V, xanthine VI and hypoxanthine VII, a derivative of said nucleobases I- VII protected at the reactive functionalities NH2 or imidic NH, a deazacarbocyclic derivative of said nucleobases I-VII optionally protected at the reactive functionality NH2. These pyrrolidine derivatives are nucleoside isosteres and can be employed for the synthesis of DNA chimeras or as termination sequences for diagnostic and therapeutic applications. Also disclosed are novel intermediates useful for the preparation of the aforementioned pyrrolidine derivatives, as well as to methods for preparing both the intermediates and the final pyrrolidine derivatives.

专利号:US-4111933-A
优先权日:1976-04-30
标题:Protection of functional groups during reaction and their subsequent restoration
发明人：ECKERT HEINER; UGI IVAR; KABBE HANS-JOACHIM
权利人:BAYER AG
摘要:In the process for preparing an organic compound of the formula n n A' -- X n n in which n X is an amino group, a hydroxyl group or a carboxyl group, and n A' is the remainder of the molecule, from an organic compound of the formula n n A -- X n n in which n A is the remainder of the molecule which can undergo reaction to form A', by converting A -- X into a compound of the formula n n A -- Z -- COOR n n in which n Z is --NH--, --O-- or a direct C--C bond, and n R is a radical of the formula ##STR1## IN WHICH Y is a direct C--C single bond, the --CHâ• CH-- group or an arylene group, n R 1 to R 4 each independently is hydrogen, halogen or an alkyl, aryl, aralkyl, alkoxycarbonyl, alkylaminocarbonyl, arylaminocarbonyl or cycloalkylaminocarbonyl radical, or n R 1 + r 2 and R 3 + R 4 each independently completes a 5- or 6-membered carbocyclic ring, or n R 1 and R 3 conjointly with the grouping --C--Y--C-- forms a carbocyclic ring with 5 or 6 carbon atoms, and Hal is halogen, n Thereby to protect X, then converting A -- Z -- COOR into a compound of the formula n n A' -- Z -- COOR n n and then treating the compound A' -- Z -- COOR to restore the group X, the improvement which comprises effecting the treatment of the compound A' -- Z -- COOR with an alkali metal compound of a complex of monovalent cobalt. The process is applicable particularly to aminocarboxylic acids including intermediates from various stages of the synthesis of penicillins and cephalosporis.