CAS: 38945-21-0; O-Allylhydroxylamine Hydrochloride

该化合物是一种多用途有机化合物,主要用作合成化学的试剂,其主要优点包括它作为合成异性循环,氧化氮和其他含氮衍生物的构件的作用.Allyl组为进一步的功能化提供了回动性,使其在医学化学和材料科学中具有价值.盐能增强稳定性和溶解性,便利处理和储存.该化合物由于其双功能性质,在点击化学和聚合物应用方面特别有用.高纯度和一贯的质量可以确保研究和工业工艺的可靠性能.

结构式图片

相似化合物

87851-77-2 3332-29-4 624-86-2

欧盟法规

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合成工艺路线路线简述

  • 合成目标产物 O-Allylhydroxylamine Hydrochloride 主要起始原料 1,3-Dichloropropene
  • (文献来源)合成步骤主要原料 1,3-Dichloropropene
N-Benzoyl-O-Allylhydroxylamine置于盐酸体系中,用 乙醇 作为反应溶剂,以50%的收率获得产物o-烯丙基羟胺盐酸盐
参考文献:Singha,A. S.; Misra,B. N.,Indian Journal Of Chemistry-Section B Organic And Medicinal Chemistry,1982,Vol. 21,# 4,P. 361-363
标题:Singha,A. S.; Misra,B. N.,Indian Journal Of Chemistry-Section B Organic And Medicinal Chemistry,1982,Vol. 21,# 4,P. 361-363

海关参考信息

专利信息


专利号:US-10717718-B2
优先权日:2015-11-17
标 题:5-azido-5-deoxy-2 :3-isopropylidene-D-arabinose compounds; their method of manufacture and their use for the synthesis of ARA-N3, KDO-N3 and 4EKDO-N3
发明人:VAUZEILLES BORIS; MAS PONS JORDI; BARON AURÈLIE
权利人:CENTRE NAT RECH SCIENT
摘要:Disclosed are new compounds of formulae: n nWherein: R 1 and R 2 can be independently H; a C 1 to C 6 alkyl including methyl, ethyl, propyl, butyl; aryl including phenyl, para-methoxyphenyl; or R 1 ,R 2 together with the carbon C-6 can be a cyclopentylidene or cyclohexylidene; each of these groups being substituted or not; and R 3 can be a C 1 to C 6 alkyl including methyl, ethyl, propyl, isopropyl, butyl, isobutyl, tert-butyl, pentyl; or aryl including phenyl, methylphenyl, ethylphenyl, each of these groups being substituted or not. The invention also relates to their method of manufacture and their use for the synthesis of Ara-N 3 , Kdo-N 3 and 4eKdo-N 3 .

专利号:US-2024390383-A1
优先权日:2021-09-28
标题 :Dioxazines and their use in treatment of gba-related diseases
发明人:NEVE SØREN; BROWN WILLIAM DALBY; THIRSTRUP KENNETH
权利人:ZEVRA DENMARK AS
摘要:The present invention relates to dioxazines, their synthesis, and their use for increasing GBA activity and/or levels as well as treatment of GBA-related diseases, such as Parkinson's disease.

专利号:EP-3377507-A1
优先权日:2015-11-17
标 题 :New 5-azido-5-deoxy-2 :3-isopropylidene-d-arabinose compounds; their method of manufacture and their use for the synthesis of ara-n3, kdo-n3 and 4ekdo-n3

专利号:US-2018370942-A1
优先权日:2015-11-17
标 题:New 5-azido-5-deoxy-2 :3-isopropylidene-d-arabinose compounds; their method of manufacture and their use for the synthesis of ara-n3, kdo-n3 and 4ekdo-n3

专利号:US-5510511-A
优先权日:1992-01-14
标 题 :Process for preparing N,O-dialkylhydroxylamine, its salts or intermediates in their synthesis
发明人:INOKI SATOSHI; TAKESUE MITSUYUKI; HASHIMOTO ISAO; KIHARA NORIAKI; SUGI KIYOAKI
权利人:MITSUI PETROCHEMICAL IND
摘要:A process for preparing N,O-dialkylhydroxycarbamic acid ester which comprises reacting hydroxylamine or its salt with dihydrocarbyl carbonate in the presence of a basic compound to prepare hydroxycarbamic acid ester and subsequently alkylating this compound with an alkylating agent; a process for recovering N,O-dialkylhydroxycarbamic acid ester which comprises azeotropically distilling the ester with water from a solution containing the ester; a process for preparing N,O-dialkylhydroxylamine which comprises hydrolyzing N,O-dialkylhydroxycarbamic acid ester in an aqueous solution or a hydrous solvent in the presence of an alkali; a process for purifying N,O-dialkylhydroxylamine hydrochloride which comprises adding aldehyde or ketone to a solution of N,O-dialkylhydroxylamine hydrochloride containing O-alkylhydroxylamine hydrochloride as impurities to convert the O-alkylhydroxylamine hydrochloride into O-alkyl aldoxime or O-alkyl ketoxime and subsequently separating the N,O-dialkylhydroxylamine hydrochloride from the reaction system; and a process for separating N,O-dialkylhydroxylamine hydrochloride which comprises (i) adding benzene or alkylated benzene to an aqueous solution containing N,O-dialkylhydroxylamine hydrochloride, azeotropically removing water or a hydrochloride solution, and, subsequently (ii)adding alcohol thereto to obtain N,O-dialkylhydroxylamine hydrochloride in the form of crystal.

专利号:EP-3170830-A1
优先权日:2015-11-17
标题:New 5-azido-5-deoxy-2 :3-isopropylidene-d-arabinose compounds ; their method of manufacture and their use for the synthesis of ara-n3, kdo-n3 and 4ekdo-n3
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合成参考文献


参考文献:10.1007/s00706-014-1319-1
摘要:Häring AP, Klahn P, Jübermann M, Mohr F, Kirsch SF. Gold(I)-catalyzed heterocyclization of β-alkynyl hydroxamic acids: synthesis of isoxazolidin-3-ones. Monatshefte für Chemie - Chemical Monthly. 2014 Nov 04;146(1):119–34. doi: 10.1007/s00706-014-1319-1.
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