CAS: 2571-54-2; 2,4,6-Trimethoxybenzonitrile

该化合物是一种有机化合物,其特点是在2,4和6个位置上存在一个苯环,代之以三个甲氧基组(-OCH3),以及1个位置上的硝酸盐组(-CN),该化合物一般是白色至白色的,在乙醇和乙酮等有机溶剂中可溶解,但由于其水分恐惧甲氧基组,其溶解性有限.硝酸性功能组的存在有助于其再活性,使其在各种化学合成和有机化学应用中有用.应参考安全数据处理和储存,如所有化学物质.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

2,4,6-trimethoxybenzaldehyde 1,2,3-trimethoxybenzene potassium cyanide 2,4,6-trimethoxybenzaldehyde oxime 2,4,6-trimethoxybenzylamine 2,4,6-trimethoxybenzonitrile N-oxide N-Trifluoracetyl-glycin-(2,4,6-Trimethoxy-benzylamid) N-(p-Methoxy-benzyloxycarbonyl)-glycin-(2,4,6-Trimethoxy-benzylamid)

合成工艺路线路线简述

    📜2,4,6-三甲氧基苯甲醛置于xy-Zeolite,盐酸羟胺体系中,化学反应 0.02H,以90%的收率获得2,4,6-三甲氧基苯甲腈
    参考文献:使用 Hy 沸石将醛非常方便和高效地一锅法转化为腈类和酮类转化为酰胺
    标题:使用 Hy 沸石将醛非常方便和高效地一锅法转化为腈类和酮类转化为酰胺
    摘要:使用 Hy-沸石作为催化剂,醛类转化为腈类和酮类转化为酰胺类可以方便有效地进行一锅法转化.研发了微波辐射和常规方法.
    Doi:10.1055/s-2002-22701

    海关参考信息

    专利信息


    专利号:US-6933303-B2
    优先权日:2001-10-19
    标 题:Heteroaryl-fused nitrogen heterocycles as therapeutic agents
    发明人:MJALLI ADNAN M M; ANDREWS ROBERT C; XIE RONGYUAN; YARRAGUNTA RAVINDRA R; REN TAN
    权利人:TRANSTECH PHARMA INC
    摘要:This invention provides compounds which are useful as inhibitors of protein tyrosine phosphatases (PTPases). As inhibitors of PTPases, the compounds of the invention are useful for the management, treatment, control and adjunct treatment of diseases mediated by PTPase activity. Such diseases include type I diabetes, type II diabetes, immune dysfunction, AIDS, autoimmunity, glucose intolerance, obesity, cancer, psoriasis, allergic diseases, infectious diseases, inflammatory diseases, diseases involving the modulated synthesis of growth hormone or the modulated synthesis of growth factors or cytokines which affect the production of growth hormone, or Alzheimer's disease.

    专利号:US-7569606-B2
    优先权日:2006-01-26
    标 题 :Platinum complexes with mononitrile-containing ligands
    发明人:XIAO ZEJUN; HAUSHEER FREDERICK H; PETLURU PAVANKUMAR
    权利人:BIONUMERIK PHARMACEUTICALS INC
    摘要:Disclosed herein are novel platinum-based complexes possessing one nitrile substituent group (mononitrile) covalently-bonded to the platinum, one or more nitrogen donor ligands capable of forming hydrogen bonds with the bases in DNA or RNA and leaving groups (i.e., L 1 and L 2 )which can be hydrolyzed iii vivo to active species, which can then form coordinate adducts with DNA or RNA at the Guanine or Adenine bases thereof. Also disclosed herein are the reaction schemes for the synthesis of said platinum complexes, as well as methods of treatment of various types of cancer by the administration of a pharmaceutically-effective dose of said novel platinum complexes.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Li, D.-D.; Wang, G.-W., Science of Synthesis: Catalytic Transformations via CH Activation, (2015) 2, 344.
    摘要:Rudzinski, D. M.; Leadbeater, N. E., Science of Synthesis: Knowledge Updates, (2012) 1, 394.
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