📜2,4,6-Tris(O-Methoxymethyl)Benzaldehyde置于palladium On Activated Charcoal 盐酸,氢氧化钾,Ad-Mix-α,氯化亚砜,甲基磺酰胺,氢气,1,8-二氮杂双环[5.4.0]十一碳-7-烯体系中,用 甲醇,乙醇,二氯甲烷,水,叔丁醇,苯 用作溶剂,化学反应 29.58H,反应生成阿夫儿茶精 参考文献:Nel,Reinier J. J.; Heerden,Pieter S. Van; Rensburg,Hendrik Van,Journal Of Chemical Research,Miniprint,1999,# 10,P. 2610-2625 标题:Nel,Reinier J. J.; Heerden,Pieter S. Van; Rensburg,Hendrik Van,Journal Of Chemical Research,Miniprint,1999,# 10,P. 2610-2625
专利号:US-2008311580-A1 优先权日:2004-03-09 标 题:Novel genes encoding proteins involved in proanthocyanidin synthesis 发明人:ABRAHAMS SHARON; ASHTON ANTHONY RICHARD; TANNER GREGORY JOHN; LARKIN PHILIP JOHN 权利人:COMMW SCIENT IND RES ORG 摘要:This inventions provides an isolated protein or polypeptide having activity in the synthesis of proanthocyanidin (PA) polymer from epicatechin or catechin in plants, and which is not naturally regulated by the TT2 or TT8 regulators, or a fragment comprising at least about 10 contiguous amino acids derived from said protein or polypeptide, particularly TDS1, TDS2, TDS3, TDS4, TDS5, or TDS6 protein, or fragment thereof. n Also provided are nucleic acid encoding such proteins or polypeptides; plant cells and plants containing and expressing such nucleic acids; antibodies that bind to such proteins or polypeptides; and related methods.
专利号:US-7126014-B2 优先权日:2000-09-05 标题 :Synthesis of epecatechin-4α, 8-epicatechin and -catechin dimers and derivatives thereof 发明人:KOZIKOWSKI ALAN P; ROMANCZYK JR LEO J; TUECKMANTEL WERNER 权利人:MARS INC 摘要:Oligomeric procyanidins containing 4α-linked epicatechin units are rare in nature and have hitherto not been accessible through stereoselective synthesis. Provided herein is the preparation of the prototypical dimer, epicatechin-4α,8-epicatechin, by reaction of the protected 4-ketones with aryllithium reagents derived by halogen/metal exchange from the aryl bromides. Removal of the 4-hydroxyl group from the resulting tertiary benzylic alcohols is effected by tri-n-butyltin hydride and trifluoroacetic acid in a completely stereoselective manner, resulting in hydride delivery exclusively from the β face.
专利号:US-2024182435-A1 优先权日:2021-05-21 标题 :Chemical synthesis method of prodelphinidin b9 gallate 发明人:CHEN SHIGUO; XU XINLEI; PAN HAIBO; YE XINGQIAN; WANG YI; CHENG HUAN; CHEN JIANLE 权利人:UNIV ZHEJIANG 摘要:The disclosure aims to provide a chemical synthesis method of a prodelphinidin B9 gallate, in which the prodelphinidin B9 gallate is synthesized by using a proanthocyanidin from Chinese bayberry leaves as a raw material, and using epigallocatechin gallate (EGCG) as a nucleophilic reagent to attack C4 sites of subunits EGCG and epigallocatechin (EGC) of the proanthocyanidin from Chinese bayberry leaves in the presence of hydrochloric acid as a catalyst. Compared with prodelphinidin B9 gallates extracted and separated from materials such as tea leaves, and Chinese bayberry leaves, the prodelphinidin B9 gallate prepared by the method provided in the present disclosure has higher purity and yield, and can be directly used as a nutrient enhancer and a natural antioxidant in the field of food.
专利号:US-6013622-A 优先权日:1998-04-15 标题:Method of regulating appetite and metabolism 发明人:BRUNO JOHN F; WHITE JEFFREY; BERELOWITZ MICHAEL; TRIPODI DANIEL; HEIL MATTHEW 权利人:NUTRICEUTICAL TECHNOLOGY CORP; UNIV NEW YORK STATE RES FOUND 摘要:Methods and compositions capable of controlling weight in an animal, preferably a human, which methods involve administering diet compositions that modulate, and preferably reduce, synthesis and secretion of neuropeptide Y (NPY) and modulate, and preferably increase synthesis and secretion of growth hormone releasing factor (GRF), compared to pre-administration amounts in the animal. The administration of such diet compositions results in a reduced appetite and a regulated metabolism that enhance weight control, including weight loss and reduction of obesity.
专利号:US-2007232495-A1 优先权日:2006-03-24 标题:Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof 发明人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L 权利人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L 摘要:The invention is related to compositions and methods that naturally protect plant tissues against ultraviolet radiation and temperature, thus giving protection against sunburn to plants, plant parts, fruits and/or flowers during their development. The invention is also related to compositions and methods to naturally improve the color of plants, plant parts, fruits and/or flowers by inducing the natural synthesis of flavonoids and anthocyanins present in plants. Likewise, the present invention is directed to improving the nutritional value of plants, plant parts, fruits and/or flowers by increasing the normal levels of polyphenolic compounds, especially flavonoids, present therein. Additionally, the present invention is related to compositions and methods that give more resistance to plants, plant parts, fruits and/or flowers against pathogens as bacteria and fungi. Finally, the present invention is related to plants, plant parts, fruits, flowers and/or propagating material treated with the compositions described in the present document.
专利号:US-2003100775-A1 优先权日:2000-09-05 标 题 :Synthesis of 4alpha-arylepicatechins