CAS: 25054-53-9; Piperonyloyl Chloride

上下游产品

CAS号94-53-1 胡椒酸 | CAS号120-57-0 胡椒醛 | CAS号326-56-7 甲基 1,3-苯并二茂-5-羧酸酯 | CAS号7719-09-7 氧氯化硫 | CAS号10026-13-8 五氯化磷 | CAS号110623-40-0 3H-1,2,4-Triazo... | CAS号4720-72-3 N-羟基苯并[d][1,3]二... | CAS号94-53-1 胡椒酸 | CAS号326-56-7 甲基 1,3-苯并二茂-5-羧酸酯 | CAS号6951-08-2 ethyl benzo[1,3... | CAS号6938-53-0 1,3-benzodioxol... | CAS号93-97-0 苯甲酸酐 | CAS号27855-25-0 (1,3-苯并二氧代l-5-基... | CAS号81581-27-3 3-(6-胡椒环基)-3-氧代丙酸乙酯 | CAS号3162-29-6 3',4'-(亚甲基二氧)苯乙酮

胡椒酸置于草酰氯,N,N-二甲基甲酰胺体系中,用 二氯甲烷 用作溶剂,化学反应 2.0H,反应生成胡椒酸酰氯
参考文献:C-F 键裂解通过 C-H 键活化实现氧化还原中性 [4+1] 环化
标题:C-F 键裂解通过 C-H 键活化实现氧化还原中性 [4+1] 环化
摘要:使用 α,α-二氟亚甲基炔作为非传统的单碳反应伙伴,报道了一种通过 Rh(III) 催化的 [4+1] 环化反应构建异吲哚啉-1-One 衍生物的合成新方法.2 倍 Cf 键断裂不仅能够在整体无氧化剂的条件下生成所需的产物,而且还会导致碳-碳三键的净迁移.此外,由于采用了温和的反应条件,本反应方案对广泛的官能团具有耐受性.
Doi:10.1021/jacs.6B12142

专利信息

专利号:US-5861532-A
优先权日:1997-03-04
标 题:Solid-phase synthesis of N-alkyl amides
发明人：BROWN EDWARD G; NUSS JOHN M
权利人:CHIRON CORP
摘要:Methods for solid phase synthesis of N-alkyl amides comprise reductive amination of carbonyl compounds using a reducing agent and an amine-containing linker bound to a solid support. The methods afford high yields of linker-bound, monoalkylated amines, and subsequent coupling with acid derivatives provide derivatized N-substituted amides in excellent yields after cleavage from the solid-phase. Compositions useful in solid phase synthesis are also described.

专利号:WO-2017135901-A1
优先权日:2016-02-05
标题 :Heterocyclic compounds, methods of synthesis and uses thereof
发明人：CHUA BOON TIN; KERI GYORGY; ORFI LASZLO; Németh Gábor; WÃ?CZEK FRIGYES; Varga Zoltán; MARKO PETER
权利人:AGENCY SCIENCE TECH & RES; VICHEM CHEMIE RES LTD
摘要:The present invention relates to 3-quinolinecarbonitrile compounds of formula (I) disclosed herein, methods for their synthesis, and uses thereof. Advantageously, the disclosed heterocyclic compounds may demonstrate enhanced efficacy in antitumor properties. Hence, the present disclosure also relates to the use of the disclosed 3-quinolinecarbonitrile compounds or pharmaceutical compositions thereof in cancer treatment.

专利号:US-8273403-B2
优先权日:2002-05-10
标题 :Generation of surface coating diversity
发明人：BARDEN MICHAEL C; KAMBOURIS PETER A
权利人:BARDEN MICHAEL C; KAMBOURIS PETER A; BIO LAYER PTY LTD
摘要:This invention relates to a surface discovery system and high-throughput combinatorial synthesis methods for generating large numbers of diverse surface coatings on solid substrates. The system is built upon a synthon which comprises at least three elements: a chemical backbone coating on the solid substrate that comprises a copolymer (B) of at least one passive constituent (P) and at least one active constituent (A); a spacer unit (S) separating the backbone from a functional group; and a functional group (F). The methods comprise the following steps: 1) selecting a plurality of synthons so that each synthon has at least two points of diversity selected from P, A, S and F; 2) applying copolymer B onto a substrate; and 3) attaching a combination of S and F to constituent A of copolymer B. Steps 2) and 3) are performed such that different synthons are generated on localized regions of the substrate.

专利号:US-5064953-A
优先权日:1983-12-29
标 题:Intermediates cephalosporin derivatives
发明人：OHNISHI HARUO; KOSUZUME HIROSHI; MIZOTA MASAHIRO; SUZUKI YASUO; MOCHIDA EI
权利人:MOCHIDA PHARM CO LTD
摘要:The present invention relates to novel cephalosporin derivatives, processes for preparing thereof, compositions for preventing and/or treating infectious diseases which comprise the novel cephalosporin derivatives as active components, and the intermediate compounds in the synthesis of cephalosporin derivatives and processes for producing thereof. The novel cephalosporin derivatives according to the present invention contain condensed heterocyclic groups, particularly a triazolopyrimidine ring or a thiadiazolopyrimidine ring as substituents at the 3-position of the cephem skeleton, and a hydroxyimino, an alkyloxyimino or an acyloxyimino moiety as substituents at the 7-position of the cephem skeleton. The compounds of the present invention containing the aforementioned substituents have a strong antibacterial activity against gram-negative bacteria and also against gram-positive bacteria including methicillin-resistant Staphylococcus aureus. These compounds are extremely useful for the treatment of infectious diseases.

专利号:US-4778805-A
优先权日:1987-06-18
标题:4,7-benzofurandione derivatives useful as inhibitors of leukotriene synthesis
发明人：ADAMS JULIAN; GUINDON YVAN; BELANGER PATRICE C; BELLEY MICHEL L; ROKACH JOSHUA
权利人:MERCK FROSST CANADA
摘要:4,7-Benzofurandione derivatives of Formula I, pharmaceutical compositions, and methods of treatment are disclosed. These compounds are useful as inhibitors of mammalian leukotriene biosynthesis. As such, these compounds are useful therapeutic agents for treating allergic conditions, asthma, cardiovascular disorders, inflammation, psoriasis and allergic conjunctivitis. The compounds are also useful as analgesics and as cytoprotective agents. Also disclosed are novel intermediates useful for the preparation of the 4,7-benzofurandiones of this invention. ##STR1##

专利号:US-2015038591-A1
优先权日:2002-05-31
标 题:Compounds, compositions and methods for the treatment of tauopathies
发明人：SNOW ALAN D; CAM JUDY A; CASTILLO GERARDO; HU QUBAI; LAKE THOMAS
权利人:PROTEOTECH INC
摘要:Bis- and tris-dihydroxyaryl compounds and their methylenedioxy analogs and pharmaceutically acceptable esters, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of tauopathies, such as Alzheimer's disease and Parkinson's disease, and the manufacture of medicaments for such treatment.