专利号:US-8722852-B2 优先权日:2006-04-28 标 题 :Cosmetic composition for stimulating the synthesis of proteins of the basement membrane 发明人:ZIEGLER HUGO; IMFELD DOMINIK; STOCKLI MARTIN; HEIDL MARC 权利人:ZIEGLER HUGO; IMFELD DOMINIK; STOCKLI MARTIN; HEIDL MARC; DSM IP ASSETS BV 摘要:Cosmetic composition which can be applied topically, comprising at least one compound of the general formula (I) in which R 1 is H, C 1 -C 20 -alkyl, cycloalkyl or aryl-C 1 -C 4 -alkyl, n is 1-4, X is —O—, —NH— or —NR 2 — and R 2 H or C 1 -C 20 -alkyl; and at least one compound corresponding to the above formula (I) but in which XR 1 with X having the possible meaning of —NH— is the residue of an alpha-amino acid; use of these compounds and of the composition for stimulating the synthesis of the proteins of the basement membrane; and also both those compounds of the formula (I) in which X is —NR 2 — and both R 1 and R 2 are different from H, and the compounds corresponding to formula (I) but in which XR 1 with X having the possible meaning of —NH— is the residue of an alpha-amino acid, as such.
专利号:US-2012094919-A1 优先权日:2009-03-16 标题 :Use of tripeptides 发明人:GRAEUB REMO; HEIDL MARC; IMFELD DOMINIK; MUELLER EIKE; WIKSTROEM PETER; ZIEGLER HUGO 权利人:GRAEUB REMO; HEIDL MARC; IMFELD DOMINIK; MUELLER EIKE; WIKSTROEM PETER; ZIEGLER HUGO 摘要:The present invention relates to the use of tripeptide derivatives for tightening, firming and/or moisturizing skin. Furthermore, the invention relates to a method for stimulating the synthesis of glycosaminoglycans containing a D-glucosamine and/or N-acetyl-D-glucosamine residue and/or proteoglycans by fibroblasts and/or keratinocytes such as in particular the synthesis of Hyaluronic acid and/or of the proteoglycans Decorin and/or Lumican.
专利号:EP-1779900-B1 优先权日:2005-10-29 标 题 :Cosmetic or dermatological composition for prevention of light-induced aging 发明人:NEUFANG HARTMUT; TILL MARTINA 权利人:APOTHEKER WALTER BOUHON GMBH 摘要:Use of a composition (I) comprising vitamin A (0.02-0.09 wt.%), phytosterol (0.1-3 wt.%), vitamin E (0.5-3 wt.%) and their biochemical precursors or derivatives, for the production of cosmetic or dermatological preparation for the inhibition of a light-induced gene expression of the synthesis of a collagenase in the skin. An independent claim is included for the cosmetic or dermatological preparation comprising (I), urea (1-4 wt.%), caprylic/capric acid triglyceride (caprylic/capric triglyceride according to INCI standard), lipids, consistency agents, emulsifying agents, polymers, perfumes, preservatives and water. ACTIVITY : Dermatological. MECHANISM OF ACTION : Gene expression of synthesis of collagenase Inhibitor.
专利号:US-8513310-B2 优先权日:2002-03-01 标题:Cosmetic use of phytosphingosine as slimming agent and cosmetic compositions comprising phytosphingosine 发明人:FRANCHI JOCELYNE; PELLICIER FRANCOISE 权利人:FRANCHI JOCELYNE; PELLICIER FRANCOISE; LVMH RECH 摘要:The invention relates to novel cosmetic uses of phytosphingosine or of one of its cosmetically acceptable salts, particularly its hydrochloride, as a slimming agent and/or as an active agent which stimulates the synthesis of leptin by adipocytes, for preparing a cosmetic composition intended for reducing subcutaneous excess fat. n The invention also relates to a method of cosmetic treatment intended for obtaining a slimming effect on the human body according to which a cosmetic composition containing phytosphingosine or one of its cosmetically acceptable salts, particularly its hydrochloride, is applied on the parts of the body to be treated. n The invention also relates to novel cosmetic compositions containing phytosphingosine or one of its cosmetically acceptable salts, particularly its hydrochloride, in combination with a lipolytic agent selected from the group consisting of CAMP and its derivatives, adenylate cyclase enzyme activating agents and phosphodiesterase enzyme inhibiting agents.
专利号:US-11850220-B2 优先权日:2020-05-19 标题 :Synthesis of ibuprofen hybrid conjugates as anti-inflammatory and analgesic agents 发明人:PANDA SIVA 权利人:UNIV RES INST INC AUGUSTA 摘要:Disclosed herein as ibuprofen hybrid conjugates and methods of their use to reduce inflammation, pain, and fever. The ibuprofen conjugates have potent anti-inflammatory and analgesic properties with low potential for ulcerogenic activity. An exemplary compound is an ibuprofen-amino acid-4-aminophenol hybrid. Also disclosed are methods of treating or reducing inflammation, pain, and fever in a subject.
专利号:EP-3485971-A1 优先权日:2017-11-21 标 题:Catalyst and process for the synthesis of fatty acid esters 发明人:LAROCCA SUSANNA; CAVANI FABRIZIO; VELASQUEZ OCHOA JULIANA; MELLONI MATTIA 权利人:SO G I S IND CHIMICA S P A; UNIV BOLOGNA ALMA MATER STUDIORUM 摘要:The present invention relates to a heterogeneous catalyst comprising silica (SiO2) and a metal co-oxide selected from the group consisting of magnesium oxide (MgO), calcium oxide (CaO), barium oxide (BaO) and zinc oxide (ZnO) and having a metal co-oxide/SiO 2 molar ratio between 0.05 and 0.3. The invention also relates to a process for preparing esters of one or more fatty acids with one or more alcohols comprising the step of reacting the one or more fatty acids with the one or more alcohols in the presence of the heterogenous catalyst, and to a process for manufacturing the heterogeneous catalyst.
摘要:S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118 摘要:International Journal of Toxicology 24(Suppl. 1):1-102, 2005 摘要:International Journal of Toxicology 34(Suppl.2):5-69, 2015 摘要:Journal of the American College of Toxicology 4(5):107-146, 1985 参考文献:10.5650/jos.ess19322 摘要:Gawas SD, Rathod VK. Ultrasound Assisted Green Synthesis of 2-Ethylhexyl Stearate: A Cosmetic Bio-lubricant. J Oleo Sci. 2020 Sep 02;69(9):1043–9. doi: 10.5650/jos.ess19322.