CAS: 20938-62-9; Pantothenate

📜泛硫醇,水 反应生成泛酸根,2-巯基乙胺
参考文献:Is Pantetheinase The Actual Identity Of Mouse And Human Vanin-1 Proteins
标题:Is Pantetheinase The Actual Identity Of Mouse And Human Vanin-1 Proteins
摘要:Pantetheinase Is An Amidohydrolase Involved In The Dissimilative Pathway Of Coa,Allowing The Turnover Of The Pantothenate Moiety. We Have Determined The N‐terminal Sequence As Well As The Sequences Of A Number Of Tryptic And Chymotryptic Peptides Of The Protein Isolated From Pig Kidney. These Sequence Stretches Were Used As Probes To Search In The Swissprot Database And Significant Similarities Were Found With A Gpi‐anchored Protein (Mouse Vanin‐1,With A Suggested Role In Lymphocyte Migration),With Two Putative Proteins Encoded By Human Cdnas (Vnn1 And Vnn2) And With Human Biotinidase. On The Basis Of Sequence Similarity,We Propose That Vanin‐1 And Vnn1 Should Be Identified As Pantetheinase.
Doi:10.1016/s0014-5793(99)01439-8

专利信息

专利号:EP-3748009-A1
优先权日:2019-06-07
标 题 :Synthesis of (r)-pantolactone acetate
发明人：BEKERLE-BOGNER MYRIA; MEDLOCK JONATHAN ALAN; STEINKELLNER GEORG; STROHMEIER GERNOT; STEINER KERSTIN
权利人:DSM IP ASSETS BV
摘要:The present invention relates to a 2-step process comprising step (1) kinetic resolution of R/S-pantolactone using an enantioselective acetylating enzyme and step (2) racemization of (S)-pantolactone in the presence of at least one specific chemical catalyst leading to highly enriched (R)-pantolactone acetate. Both step (1) and (2) might be carried-out in a one-pot reaction/system.

专利号:US-2024191270-A1
优先权日:2021-04-16
标 题 :Fermentative production
发明人：BEAUPREZ JOERI; COUSSEMENT PIETER; DECOENE THOMAS
权利人:INBIOSE NV
摘要:The present invention is in the technical field of synthetic biology and metabolic engineering. More particularly, the present invention is in the technical field of metabolically engineered cells and use of said cell in a cultivation, preferably a fermentation. The present invention describes a cell for the production of a compound. The cell comprises a pathway for the production of the compound, which can be a disaccharide, oligosaccharide and/or a Neu(n)Ac-containing bioproduct, wherein (n) is 4, 5, 7, 8 or 9 or a combination thereof. The cell is metabolically engineered for enhanced synthesis of acetyl-Coenzyme A. The invention also resides in a method of producing such compound by cultivation, preferably a fermentation, with such a cell.

专利号:US-2011207183-A1
优先权日:2008-04-30
标 题 :Production Process for Fine Chemicals Using Microorganisms with Reduced Isocitrate Dehydrogenase Activity
发明人：HEROLD ANDREA; SCHROEDER HARTWIG; JEONG WEOL KYU; KLOPPROGGE CORINNA; ZELDER OSKAR; HAEFNER STEFAN; RICHTER ULRIKE; BECKER JUDITH; WITTMANN CHRISTOPH
权利人:BASF SE
摘要:The present invention is directed to a method utilizing a microorganism with reduced isocitrate dehydrogenase activity for the production of fine chemicals. Said fine chemicals may be amino acids, monomers for polymer synthesis, sugars, lipids, oils, fatty acids or vitamins and are preferably amino acids of the aspartate family, especially methionine or lysine, or derivatives of said amino acids, especially cadaverine. Furthermore, the present invention relates to a recombinant microorganism having a reduced isocitrate dehydrogenase activity in comparison to the initial microorganism and the use of such microorganisms in producing fine chemicals such as aspartate family amino acids and their derivatives.