CAS: 824-46-4; 2-Methoxyhydroquinone

• 英文名称2-Methoxyhydroquinone
• 中文名称2-甲氧基对苯二酚
• IUPAC名称2-methoxybenzene-1,4-diol
• 其它别名2,5-Dihydroxyanisole; 2-Methoxybenzene-1,4-diol
• CAS编号824-46-4
• MFCD编号:MFCD00013971
• EINECS号:212-530-1
• FDA UNII编号:2HI6HNR5U1
• 分子式:C7H8O3
• 分子量:140.14
• 产品CID: 1815252
• 产品分类化学试剂 → 有机试剂 → 脂肪酮(含烯醇)

• 相似结构搜索
• 产品信息参考;
• InChIKey: LAQYHRQFABOIFD-UHFFFAOYSA-N
• InChI=1S/C7H8O3/c1-10-7-4-5(8)2-3-6(7)9/h2-4,8-9H,1H3…
• 计算化学: 氢键受体数3.0氢键供体数2.0可旋转键数1.0

物理性质

• 熔点88-91  °C(文献)
• 沸点311.3±22.0 °C at 760 mmHg
• 闪点142.1±22.3 °C
• 密度1.3±0.1 g/cm3
• pKa:10.30±0.18(预测)
• PSA:49.69
• LogP:0.47
• 折射率1.580
• 蒸汽压0.0±0.7 mmHg at 25°C
• 溶解性DMF: 2 mg/mL,DMSO: 5 mg/mL,Ethanol: 10 mg/mL
• 敏感性常温常压下稳定，避免强氧化剂接触
• 外观形态橙棕色至棕色和灰色结晶粉末和块状物
• 储存条件储存在 -20°C
• 产品应用该化合物用于白腐菌真菌TRAMETES用FERUC酸制造的醇.

MSDS等安全信息

• GHS象形图
• GHS符号GHS07;
  注释: Exclamation mark
• 危险类别特定目标器官毒性 - 单次接触 类别3
  皮肤腐蚀/刺激 类别2
  严重眼刺激 类别2
• 警示词Warning(警告)
• 危险描述H335 |可能引起呼吸道刺激.
  H315 |造成皮肤刺激.
  H319 |造成严重眼刺激.
• 防范说明P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
• UN编号NONH for all modes of transport
• 危险品标志Xi
• 风险等级Irritant
• 安全声明22-24/25
• 危险类别码36/37/38
• WGK Germany3

欧盟法规

上下游产品

合成工艺路线路线简述

• 合成目标产物 2-Methoxyhydroquinone 主要起始原料 2-Methoxyhydroquinone
• 2880-58-2 = 824-46-4
  反应条件:1.1 Reagents: Chlorotrimethylsilane,1,1,3,3-Tetramethyldisiloxane,Sodium Iodide Solvents: Dichloromethane
  标题:Ionic And Organometallic-Catalyzed Organosilane Reductions
  作者:Larson,Gerald L.; Et Al
  参考文献:Organic Reactions (Hoboken 日期:2008 卷标:71 页码:1-737]
  
  2880-58-2 = 824-46-4
  反应条件:1.1 Reagents: Chlorotrimethylsilane,1,1,3,3-Tetramethyldisiloxane,Sodium Iodide Solvents: Acetonitrile,Dichloromethane
  标题:Reagents And Synthetic Methods. 57. Reduction Of Carbonyl Compounds Promoted By Silicon Hydrides Under The Influence Of Trimethylsilyl-Based Reagents
  作者:Aizpurua,Jesus M.; Et Al
  参考文献:Canadian Journal Of Chemistry 日期:1986 卷标:64(12) 页码:2342-7]
  
  121-33-5 = 824-46-4
  反应条件:1.1 Reagents: Sodium Percarbonate Solvents: Tetrahydrofuran,Water; Overnight,25 °C1.2 Reagents: Hydrochloric Acid Solvents: Water; Ph 1,25 °C
  标题:Epoxy Thermosets From Model Mixtures Of The Lignin-To-Vanillin Process
  作者:Fache,M.; Et Al
  参考文献:Green Chemistry 日期:2016 卷标:18(3) 页码:712-725]
  
  121-34-6 = 824-46-4 [标题:Reaction Conditions
  标题:Oxidative Decarbonylation Of Phenolic Acids By Singlet Oxygen
  作者:Chibber,S. S.; Et Al
  参考文献:Indian Journal Of Chemistry 日期:1982 卷标:(4) 页码:352-3]
  
  121-34-6 = 824-46-4 [标题:Reaction Conditions
  标题:Vanillic Acid Metabolism By Sporotrichum Pulverulentum: Evidence For Demethoxylation Before Ring Cleavage
  作者:Ander,Paul; Et Al
  参考文献:Archives Of Microbiology 日期:1983 卷标:136(1) 页码:1-6]
  
  61654-67-9 = 824-46-4
  反应条件:1.1 Reagents: Butyllithium,N,N,N′,N′-Tetramethylethylenediamine
  标题:The Generation Of C,O,O-Trilithiated Derivatives Of Dihydric Phenols
  作者:Saa,Jose M.; Et Al
  参考文献:Tetrahedron Letters 日期:1991 卷标:32(49) 页码:7313-16]
  
  1135-24-6 = 824-46-4 [标题:Reaction Conditions
  标题:Metabolism Of Trans-Ferulic Acid By The White-Rot Fungus Sporotrichum Pulverulentum
  作者:Grupta,Jugal K.; Et Al
  参考文献:Archives Of Microbiology 日期:1981 卷标:128(4) 页码:349-54]
  
  537-98-4 = 824-46-4 [标题:Reaction Conditions
  标题:Vanillin As A Product Of Ferulic Acid Biotransformation By The White-Rot Fungus Pycnoporus Cinnabarinus I-937: Identification Of Metabolic Pathways
  作者:Falconnier,B.; Et Al
  参考文献:Journal Of Biotechnology 日期:1994 卷标:37(2) 页码:123-32]
  
  90-05-1 = 824-46-4
  反应条件:1.1 Solvents: Dimethylformamide,Water; 60 Min,Ph 6.5,37 °C
  标题:Saturation Mutagenesis Of Burkholderia Cepacia R34 2,4-Dinitrotoluene Dioxygenase At Dntac Valine 350 For Synthesizing Nitrohydroquinone,Methylhydroquinone,And Methoxyhydroquinone
  作者:Keenan,Brendan G.; Et Al
  参考文献:Applied And Environmental Microbiology 日期:2004 卷标:70(6) 页码:3222-3231]
  
  90-05-1 = 824-46-4
  反应条件:1.1 Reagents: Oxygen Catalysts: Cuprous Chloride Solvents: Acetonitrile,Water; 3 H,2 Mpa,50 °C2.1 Reagents: Sodium Dithionite Solvents: Water; 0.5 - 1 H,Rt
  标题:Selective Activation Of C-H Bond Into C=o Bond Of Phenols In Para-Position Via Aerobic Oxidation
  作者:Yang,Shilei; Et Al
  参考文献:Catalysis Communications 日期:2019 卷标:123 页码:105-108]
  
  121-34-6 = 824-46-4 + 121-33-5
  反应条件:1.1 Reagents: Maltose,Diammonium Tartrate Solvents: Water; 7 D,30 °C
  标题:A Two-Step Bioconversion Process For Vanillin Production From Ferulic Acid Combining Aspergillus Niger And Pycnoporus Cinnabarinus
  作者:Lesage-Meessen,Laurence; Et Al
  参考文献:Journal Of Biotechnology 日期:1996 卷标:50 页码:107-113]
  
  498-02-2 = 824-46-4 + 57244-88-9
  反应条件:1.1 Reagents: Acetic Acid,Peracetic Acid Solvents: Water; 1 H,Ph 3,60 °C
  标题:The Baeyer-Villiger Oxidation Of Ketones And Aldehydes
  作者:Krow,Grant R.
  参考文献:Organic Reactions (Hoboken 日期:1993 卷标:43]
  
  90-05-1 = 824-46-4 + 6100-60-3
  反应条件:1.1 Catalysts: Toluene Monooxygenase
  标题:Alanine 101 And Alanine 110 Of The Alpha Subunit Of Pseudomonas Stutzeri Ox1 Toluene-O-Xylene Monooxygenase Influence The Regiospecific Oxidation Of Aromatics
  作者:Vardar,Gonul; Et Al
  参考文献:Biotechnology And Bioengineering 日期:2005 卷标:92(5) 页码:652-658]
  
  2880-58-2 = 824-46-4
  反应条件:1.1 Reagents: Sodium Dithionite Solvents: Water; 0.5 - 1 H,Rt
  标题:Selective Activation Of C-H Bond Into C=o Bond Of Phenols In Para-Position Via Aerobic Oxidation
  作者:Yang,Shilei; Et Al
  参考文献:Catalysis Communications 日期:2019 卷标:123 页码:105-108]
  
  121-33-5 = 824-46-4
  反应条件:1.1 Reagents: Sodium Carbonate,Hydrogen Peroxide Solvents: Water; Rt
  标题:Amine Hardeners And Epoxy Cross-Linker From Aromatic Renewable Resources
  作者:Fache,Maxence; Et Al
  参考文献:European Polymer Journal 日期:2015 卷标:73 页码:344-362]
  
  121-33-5 = 824-46-4
  反应条件:1.1 Reagents: Sodium Carbonate Solvents: Tetrahydrofuran,Water; Rt; 3 H,Rt1.2 Reagents: Hydrochloric Acid Solvents: Water; Ph 3
  标题:New Vanillin-Derived Diepoxy Monomers For The Synthesis Of Biobased Thermosets
  作者:Fache,Maxence; Et Al
  参考文献:European Polymer Journal 日期:2015 卷标:67 页码:527-538]
  
  498-02-2 = 824-46-4
  反应条件:1.1 Reagents: Sodium Percarbonate Solvents: Tetrahydrofuran,Water; Overnight,25 °C1.2 Reagents: Hydrochloric Acid Solvents: Water; Ph 1,25 °C
  标题:Epoxy Thermosets From Model Mixtures Of The Lignin-To-Vanillin Process
  作者:Fache,M.; Et Al
  参考文献:Green Chemistry 日期:2016 卷标:18(3) 页码:712-725]
  
  139209-92-0 = 824-46-4
  反应条件:1.1 Reagents: Butyllithium,N,N,N′,N′-Tetramethylethylenediamine
  标题:The Generation Of C,O,O-Trilithiated Derivatives Of Dihydric Phenols
  作者:Saa,Jose M.; Et Al
  参考文献:Tetrahedron Letters 日期:1991 卷标:32(49) 页码:7313-16]
  
  121-34-6 = 824-46-4 [标题:Reaction Conditions
  标题:Vanillate Hydroxylase From The White Rot Basidiomycete Phanerochaete Chrysosporium
  作者:Yajima,Yasuo; Et Al
  参考文献:Archives Of Microbiology 日期:1979 卷标:123(3) 页码:319-21]
  
  150-19-6 = 824-46-4
  反应条件:1.1 Solvents: Dimethylformamide,Water; 60 Min,Ph 6.5,37 °C
  标题:Saturation Mutagenesis Of Burkholderia Cepacia R34 2,4-Dinitrotoluene Dioxygenase At Dntac Valine 350 For Synthesizing Nitrohydroquinone,Methylhydroquinone,And Methoxyhydroquinone
  作者:Keenan,Brendan G.; Et Al
  参考文献:Applied And Environmental Microbiology 日期:2004 卷标:70(6) 页码:3222-3231]
  
  73759-43-0 = 824-46-4
  反应条件:1.1 Reagents: (T-4)-Chlorodioxo(1,1,1-Trimethylsilanolato)Chromium Solvents: Dichloromethane
  标题:Reagents And Synthetic Methods. 45. Synthetic Applications Of Chromium(Vi) Reagents In Combination With Chlorotrimethylsilane
  作者:Cossio,Fernando P.; Et Al
  参考文献:Canadian Journal Of Chemistry 日期:1986 卷标:64(2) 页码:225-31]
  
  = 824-46-4
  反应条件:1.1 Reagents: (T-4)-Chlorodioxo(1,1,1-Trimethylsilanolato)Chromium Solvents: Dichloromethane
  标题:Reagents And Synthetic Methods. 45. Synthetic Applications Of Chromium(Vi) Reagents In Combination With Chlorotrimethylsilane
  作者:Cossio,Fernando P.; Et Al
  参考文献:Canadian Journal Of Chemistry 日期:1986 卷标:64(2) 页码:225-31]
  
  9005-53-2 = 824-46-4
  反应条件:1.1 -2.1 Reagents: Sodium Percarbonate Solvents: Tetrahydrofuran,Water; Overnight,25 °C2.2 Reagents: Hydrochloric Acid Solvents: Water; Ph 1,25 °C
  标题:Epoxy Thermosets From Model Mixtures Of The Lignin-To-Vanillin Process
  作者:Fache,M.; Et Al
  参考文献:Green Chemistry 日期:2016 卷标:18(3) 页码:712-725]
  
  1135-24-6 = 824-46-4 + 121-34-6
  反应条件:1.1 Reagents: Maltose,Diammonium Tartrate Solvents: Water; 7 D,30 °C
  标题:A Two-Step Bioconversion Process For Vanillin Production From Ferulic Acid Combining Aspergillus Niger And Pycnoporus Cinnabarinus
  作者:Lesage-Meessen,Laurence; Et Al
  参考文献:Journal Of Biotechnology 日期:1996 卷标:50 页码:107-113]
  
  1135-24-6 = 824-46-4 + 121-33-5
  反应条件:1.1 Reagents: Maltose,Diammonium Tartrate Solvents: Water; 7 D,30 °C2.1 Reagents: Maltose,Diammonium Tartrate Solvents: Water; 7 D,30 °C
  标题:A Two-Step Bioconversion Process For Vanillin Production From Ferulic Acid Combining Aspergillus Niger And Pycnoporus Cinnabarinus
  作者:Lesage-Meessen,Laurence; Et Al
  参考文献:Journal Of Biotechnology 日期:1996 卷标:50 页码:107-113

海关参考信息

• 2905110000-甲醇
  2907210001-间苯二酚
  2907221000-对苯二酚
  2908199090-其他酚的卤化衍生物
• 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
• 详情请参考：📖 海关编码查询和海关进出口税则

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