CAS: 759-58-0; Ethyl 2-Cyano-3-Methylbut-2-Enoate

相似化合物

6666-75-7 7085-85-0 686-33-9

上下游产品

ethyl 2-cyanoacetate acetone diazomethane ethyl 2-cyanobut-2-enoateethyl 2-isopropylcyanoacetate 2-cyano-3,3-dimethyl-heptanoic acid ethyl ester ethyl 1,2,2-tricyano-3,3-dimethylcyclopropane-1-carboxylate 2,2-dimethylsuccinic acid

氰乙酸乙酯,丙酮置于lithium Bromide体系中,化学反应 18.0H,以66%的收率获得产物2-氰基-3-甲基丁烯酸乙酯
参考文献:(+/-)-(z)-和(+/-)-(e)-9-(溴亚甲基)-1,5,5-三甲基螺[5.5] Undeca-1,7-Dien-3-One和(+/-)-Majusculone
标题:(+/-)-(z)-和(+/-)-(e)-9-(溴亚甲基)-1,5,5-三甲基螺[5.5] Undeca-1,7-Dien-3-One和(+/-)-Majusculone
摘要:香米草倍半萜类化合物(z)-9-(溴亚甲基)-1,5,5-三甲基螺[5.5] Undeca-1,7-二烯-3-酮及其15-E表基的新的全合成已于2007年完成. 13个步骤.在我们的序列中,Diels-Alder反应和随后的加合物还原烷基化被用作关键策略,以创建具有合适功能性的a环和季螺中心,以接近b环.此外,还可以通过两步轻松地从高级中间体完全合成去甲香豆素天然产物(+/-)-大丁烯酮. 变体-倍半萜-大枣-总合成-Diels-Alder反应
DOI:10.1055/s-0030-1258412

专利信息

专利号:US-7323589-B2
优先权日:2000-10-26
标 题:Intermediates for use in retinoid synthesis
发明人：VALLA ALAIN; CARTIER DOMINIQUE; LABIA ROGER; POTIER PIERRE JEAN-PAUL
权利人:CENTRE NAT RECH SCIENT
摘要:The invention concerns compounds of formula (1) wherein in particular G represents the —N(CH 3 ) 2 —, —N(C 2 H 5 ) 2 -group or N-pyrrolidine: n is an integer equal to 1 or 2: R 1 , R 2 and R 3 , independently of one another, represent a hydrogen atom or a methyl group, the successive unsaturated units capable of being moreover identical or different, provided that at least one of the substituents R 1 , R 2 and R 3 is different from H: and Y 1 and Y 2 represent each a —COOCH 3 group or a COOC 2 H 5 group.

专利号:US-6136982-A
优先权日:1999-01-22
标 题:Synthesis of 3-amino-2-chloro-4-methylpyridine from acetone and ethyl cyanoacetate
发明人：GROZINGER KARL
权利人:BOEHRINGER INGELHEIM PHARMA
摘要:A method for making 3-amino-2-chloro-4-methylpyridine from acetone and ethyl cyanoacetate, as depicted in the following reaction scheme. ##STR1##

专利号:RU-2012554-C1
优先权日:1989-01-24
标 题:Method of synthesis of benzocycloalkenyldihydrooxyalkanoic acid derivatives

专利号:WO-0043364-A1
优先权日:1999-01-22
标题:Synthesis of 3-amino-2-chloro-4-methylpyridine from acetone and ethyl cyanoacetate

专利号:EP-1070053-B1
优先权日:1999-01-22
标题:Synthesis of 3-amino-2-chloro-4-methylpyridine from acetone and ethyl cyanoacetate

专利号:EP-1070053-A1
优先权日:1999-01-22
标题 :Synthesis of 3-amino-2-chloro-4-methylpyridine from acetone and ethyl cyanoacetate