CAS: 68194-17-2; 2,2',3,3',4,5,5',6-Octachlorobiphenyl
该化合物是一种合成有机化合物,其复杂结构由两只双联环组成,8个氯原子在不同位置被替换,该化合物是更大的多氯联苯群体的一部分,众所周知,多氯联苯具有化学稳定性,疏水性和耐降解性,使其具有持久性环境污染物. 2,2',3',3',4,5,5',5',5',6-八氯联苯通常没有色,光黄色和表现出低挥发性.它溶解于水中,但有机溶剂中可溶解,这助长了其在食物链中的生物累积.由于其毒性特性,包括潜在的致癌效应和内分泌干扰,许多国家对其使用严重限制或禁止.环境监测和补救工作正在进行,以解决与多氯联苯有关的污染,包括这一特定化合物,强调了解其行为和生态系统影响的重要性.
- 英文名称2,2',3,3',4,5,5',6-Octachlorobiphenyl
- 中文名称2,2’,3,3’,4,5,5’,6-八氯联苯
- IUPAC名称1,2,3,4,5-pentachloro-6-(2,3,5-trichlorophenyl)benzene
- 其它别名2,2',3,3',4,5,5',6-°Ctachlorobiphenyl; 2,3,4,5,6,2',3',5'-°Ctachlorobiphenyl
- CAS编号68194-17-2
- MFCD编号:MFCD00152683
- FDA UNII编号:881FKL14GM
- 分子式:C12H2Cl8分子量:429.77
- 产品CID: 1670758
- 产品分类分析化学 → 食品安全 → 二噁英，多氯联苯，呋喃
物理性质
MSDS等安全信息
- 危险描述Not Classified
Reported as not meeting GHS hazard criteria by 3 of 3 companies. For more detailed information, please visit ECHA C&L website. - 安全声明The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcription of genes, mainly be inducing the expression of hepatic Phase I and Phase II enzymes, especially of the cytochrome P450 family. Most of the toxic effects of PCBs are believed to be results of Ah receptor binding. Other PBCs are believed to interfere with calcium channels and/or change brain dopamine levels. PCBs can also cause endocrine disurption by altering the production of thyroid hormones and binding to estrogen receptors, which can stimulate the growth of certain cancer cells and produce other estrogenic effects, such as reproductive dysfunction. They will bioaccumulate by binding to receptor proteins such as uteroglobin. (A3, A4, A30, A66)
上下游产品
2,3,5-trichloroaniline pentachlorobenzene 2,3,4,5,6-pentachloroiodobenzene 1,2,5-trichloro-3-iodobenzene合成工艺路线路线简述
- 合成目标产物 2,2',3,3',4,5,5',6-Octachlorobiphenyl 主要起始原料 2,3,5-Trichloroaniline And Pentachlorobenzene
- (文献来源)合成步骤主要原料 2,3,5-Trichloroaniline 和 Pentachlorobenzene
📜三氯苯胺,五氯苯置于亚硝酸异戊酯体系中,化学反应生成 2,2',3,3',4,5,5',6-八氯联苯
参考文献:Physical,Spectral And Chromatographic Properties Of All 209 Individual Pcb Congeners
标题:Physical,Spectral And Chromatographic Properties Of All 209 Individual Pcb Congeners
摘要:Physical,Spectral And Chromatographic Data For All 209 Individual Pcb Congeners Is Presented. The Individual Congeners Were Synthesized And Then Isolated And Purified. Recent Emphasis On The Source Of The Toxicity Of Commercial Pcb Formulations Has Increased The Need For A Complete Set Of The Pcb Congeners. Through The Use Of Two Capillary Gc Columns: 40% octadecyl/ 15% Phenyl Methyl Siloxane And 50% Phenyl Methyl Siloxane,It Was Possible To Separate 201 Pcb Congeners With Only Four Unresolved Pairs. The Data Compiled In This Study For All 209 Congeners Will Aid In The Identification Of Selected Individual Components Of These Environmental Pollutants. The Use Of This Data Also Presents The Opportunity For The Improved Quantification Of The Commercial Pcb Formulations.
DOI:10.1016/0045-6535(95)00140-4
海关参考信息
- 2903911000-邻二氯苯
- 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
摘要:T14: Lewis RJ (1996). Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold.
摘要:L4: ATSDR - Agency for Toxic Substances and Disease Registry (2000). Toxicological profile for polychlorinated biphenyls. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA).
摘要:L134: ATSDR - Agency for Toxic Substances and Disease Registry (2001). Minimal Risk Levels (MRLs) for Hazardous Substances. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA).
摘要:L135: International Agency for Research on Cancer (2014). IARC Monographs on the Evaluation of Carcinogenic Risks to Humans.
摘要:T6: World Health Organization (1993). Environ Health Criteria 140: Polychlorniated Biphenyls and Terphenyls.
📝 需求与反馈
尽可能描述清楚需求与问题信息
