CAS: 67381-50-4; 4-(1-Carboxyethyl)Benzoic Acid

该化合物是一种碳箱酸衍生物,其成分包括苯环和乙酸替代物,在阿尔法位置上又增加了一个甲基组,该化合物因其双功能反应性,能够用作制造更复杂的分子的中间体,因此对有机合成和制药应用感兴趣;芳香和碳箱基组的存在允许多种化学改变,如洗涤或恐吓;其结构特性使其适合医药化学应用,特别是用于开发非类动物抗炎药物和其他生物活性化合物;产品通常以高纯度供应,以确保合成工艺的一致性能.

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362052-00-4 43153-07-7 3076430-28-6

上下游产品

(R,S)-2-(4'-methylphenyl) propionic acid 4-n-chlorophenylacetylene carbon monoxide 4-(1-methoxycarbonyl-ethyl)-benzoic acid methyl ester 4-(1-methoxycarbonyl-ethyl)-benzoic acid methyl ester

合成工艺路线路线简述

    📜2-(4-甲基苯基)丙酸置于alkaline Permanganate体系中,化学反应生成 4-羧基-Alpha-甲基苯乙酸
    参考文献:Errera,Gazzetta Chimica Italiana,1891,Vol. 21 I,P. 98
    标题:Errera,Gazzetta Chimica Italiana,1891,Vol. 21 I,P. 98

    海关参考信息

    专利信息


    专利号:US-7125906-B2
    优先权日:2002-04-03
    标题 :Indole derivatives having anti-angiogenetic activity
    发明人:ARNOULD JEAN-CLAUDE
    权利人:ASTRAZENECA AB
    摘要:The invention relates to the use of a compound of Formula (I), for the manufacture of a medicament to inhibit and/or reverse and/or alleviate symptoms of angiogenesis and/or any disease state associated with angiogenesis: n nwherein: X, p, q, R 1 , R 2 , R 3 , R 4 , and R 5 are as defined in the description. The invention also related to use of compounds of Formula (I) as medicaments and also to novel compounds of Formula (I). The invention further provides pharmaceutical compositions of compounds of Formula (I) and processes for the synthesis of compounds of Formula (I).

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1007/978-3-030-26668-4_7
    摘要:Boudjemaa A, Gómez-Ruiz S. Titanium Oxide-Based Nanomaterials with Photocatalytic Applications in Environmental Chemistry. 2020. In: Environmental Chemistry for a Sustainable World.
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