(3,5,6-三氯-2-吡啶基)氧基-乙酸乙酯置于甲醇,Sodium Hydroxide体系中,用 四氢呋喃,水 作为反应溶剂,以0.62 G的收率获得产物绿草定 参考文献:Monitoring Of The Organophosphate Pesticide Chlorpyrifos In Vegetable Samples From Local Markets In Northern Thailand By Developed Immunoassay 标题:Monitoring Of The Organophosphate Pesticide Chlorpyrifos In Vegetable Samples From Local Markets In Northern Thailand By Developed Immunoassay 摘要:氯氰菊酯是一种有机磷杀虫剂,广泛用于农民进行作物保护.然而,人们对其在环境和食物链中的污染存在担忧.在本研究中,开发并验证了一种用于检测氯氰菊酯的室内间接竞争酶联免疫吸附测定法(ic-Elisa),并与气相色谱-火焰光度检测(gc-Fpd)作为传统方法进行了比较.开发的ic-Elisa被用于检测蔬菜样品中的氯氰菊酯残留.开发的ic-Elisa对氯氰菊酯表现出非常好的灵敏度,Ic50为0.80 µg/kg,对其他有机磷杀虫剂的交叉反应性低.从泰国北部的清莱,清迈和南府的当地市场收集了160个样品.蔬菜样品中氯氰菊酯残留的阳性率为33.8%,黄瓜,香菜和空心菜中发现的氯氰菊酯水平最高,分别为275,145和35.3 µg/kg.在检测到的样品中,氯氰菊酯的最高中位数水平分别为大白菜(332 μg/kg),黄瓜(146.3 μg/kg)和芥兰(26.95 μg/kg).开发的ic-Elisa适用于快速定量氯氰菊酯残留. DOI:10.3390/ijerph17134723
专利号:WO-2024256370-A1 优先权日:2023-06-13 标 题 :Synthesis of glufosinate using an amidase-based process 发明人:ZIMMERMANN GUNTHER; POTT MORITZ STEFAN 权利人:BASF SE 摘要:The present invention relates to a method of preparing glufosinate, comprising the steps of hydrolysing an N-carbamoyl glufosinate amide with an Amidase enzyme to form an N- carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N- carbamoyl amino acid compound.
专利号:US-2025120400-A1 优先权日:2021-12-10 标题:Synthesis of glufosinate using a hydantoinase-based process 发明人:DITRICH KLAUS; BREUER MICHAEL; POTT MORITZ STEFAN; ZIMMERMANN GUNTHER; SEEMAYER STEFAN 权利人:BASF SE 摘要:The present invention relates to a method of manufacturing glufosinate, comprising the steps of hydrolysing a hydantoin with a Hydantoinase enzyme to form a N-carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N-carbamoyl amino acid compound.
专利号:US-11919928-B2 优先权日:2016-03-16 标题 :Method for producing dihydrotentoxin 发明人:KUBO TAKASHI; MACHIDA MASAYUKI; FUJIOKA TOMONORI; YAMAGUCHI Shigenari; KAWAI KIYOSHI 权利人:KUMIAI CHEMICAL INDUSTRY CO 摘要:An object of the present invention is to identify an enzyme having activity of synthesizing dihydrotentoxin that is a tentoxin precursor and an enzyme having activity of synthesizing tentoxin using dihydrotentoxin as a substrate. The present invention concerns a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 16 and having activity of nonribosomal peptide synthesis of dihydrotentoxin and a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 18 and having activity of converting dihydrotentoxin to tentoxin.
专利号:US-2021386068-A1 优先权日:2018-11-07 标题 :Compositions comprising pyridine carboxylate herbicides and very long chain fatty acid (vlcfa) synthesis inhibitor herbicides 发明人:KISTER JEREMY; SATCHIVI NORBERT M 权利人:CORTEVA AGRISCIENCE LLC 摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a VLCFA synthesis inhibitor herbicide. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof, and (b) a VLCFA synthesis inhibitor herbicide.
专利号:US-2021352899-A1 优先权日:2018-11-07 标题 :Compositions comprising pyridine carboxylate herbicides and fatty acid and lipid synthesis inhibitor herbicides 发明人:KISTER JEREMY; SATCHIVI NORBERT M 权利人:CORTEVA AGRISCIENCE LLC 摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a fatty acid and lipid synthesis inhibitor (FA/LSI) herbicide, an agriculturally acceptable salt or ester thereof, or mixtures thereof. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a fatty acid and lipid synthesis inhibitor (FA/LSI) herbicide, an agriculturally acceptable salt or ester thereof, or mixtures thereof.
专利号:ES-2717283-T3 优先权日:2012-07-24 标 题:Herbicidal compositions comprising 4-amino-3-chloro-5-fluoro-6- (4-chloro-2-fluoro-3-methoxyphenyl) pyridine-2-carboxylic acid or a derivative thereof and herbicides inhibitors of VLCFA synthesis and synthesis of fatty acids / lipids
1: Pandey A, Sharma S, Jain R. Voltammetric sensor for the monitoring of hazardous herbicide triclopyr (TCP). J Hazard Mater. 2019 Apr 5;367:246-255. doi: 10.1016/j.jhazmat.2018.12.083. Epub 2018 Dec 23. doi: 10.1016/j.ecoenv.2018.02.035. Epub 2018 Feb 27. doi: 10.1007/s10661-017-6236-4. doi: 10.1007/s00267-017-0867-7. Epub 2017 Apr 19. doi: 10.1002/etc.3767. Epub 2017 Mar 21. doi: 10.1080/03601234.2015.1028835. doi: 10.1080/03601234.2015.982419. doi: 10.1007/s10653-014-9673-9. Epub 2015 Jan 3. Erratum in: Environ Geochem Health. 2016 Oct;38(5):1215. doi: 10.1107/S160053681401681X. eCollection 2014 Sep 1. 11: Guilherme S, Santos MA, Gaivão I, Pacheco M. Genotoxicity evaluation of the herbicide Garlon(®) and its active ingredient (triclopyr) in fish (Anguilla anguilla L.) using the comet assay. Environ Toxicol. 2015 Sep;30(9):1073-81. doi: 10.1002/tox.21980. Epub 2014 Mar 13. doi: 10.1080/03601234.2013.780943. doi: 10.1016/j.talanta.2012.03.060. Epub 2012 May 10. doi: 10.1007/s00204-011-0734-x. Epub 2011 Jul 16. doi: 10.1080/03601234.2011.559424. doi: 10.3109/15563650.2010.526944. doi: 10.1021/jf803282f. doi: 10.1016/j.talanta.2006.07.015. Epub 2006 Aug 23. Epub 2006 Nov 28. Epub 2005 Dec 13.
合成参考文献
参考文献:10.1007/s00204-011-0734-x 摘要:Kimura O, Tsukagoshi K, Hayasaka M, Endo T. Uptake of triclopyr (3,5,6-trichloro-2-pyridinyloxyacetic acid) and dicamba (3,6-dichloro-2-methoxybenzoic acid) from the apical membranes of the human intestinal Caco-2 cells. Arch Toxicol. 2012 Jan;86(1):55–61. doi: 10.1007/s00204-011-0734-x.