CAS: 166737-85-5; H-Cys(Trt)-Nh2
该化合物是一种含硫磺的手性氨基酸衍生物,具有三苯基甲基(三丁基)保护组,在硫酸盐混合物中具有保护组,该化合物在peptide合成和有机化学方面特别宝贵,三丁基混合物为硫醇功能提供选择性保护,从而能够在温和酸条件下有控制的去保护;其立体化学纯度(R-配置)确保非对称合成中精确的性能感应;氨基化合物进一步增强了其在建立peptide脊椎或作为进一步功能化的前体的效用.该试剂有利于其稳定性,处理便利性以及符合标准的联结协议,从而成为先进的合成应用的可靠选择.
- 英文名称H-Cys(Trt)-Nh2
- 中文名称S-三苯甲基-L-半胱氨酰胺
- IUPAC名称(R)-2-amino-3-(tritylthio)propanamide
- 其它别名S-三苯甲基-L-半胱氨酰氨; S-Trityl-L-Cysteine Amide Hydrochloride
- CAS编号166737-85-5
- MFCD编号:MFCD22126061
- EINECS号:963-506-9
- 分子式:C22H22N2OS分子量:362.49
- 产品CID: 844246
- 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物
相似化合物
2799-07-7 25840-82-8 725728-41-6物理性质
MSDS等安全信息
欧盟法规
C&L通报上下游产品
CAS号58885-35-1 S-trityl-L-cyst...合成工艺路线路线简述
📜S-Trityl-L-Cysteine Methyl Ether置于氨体系中,用 甲醇 用作溶剂,化学反应 14.0H,以57%的收率获得s-三苯甲基-L-半胱氨酰胺
参考文献:Acetylenic Sulfonamide Thiol Tace Inhibitors
标题:Acetylenic Sulfonamide Thiol Tace Inhibitors
海关参考信息
- 2902300000-甲苯
2912110000-甲醛
2912120000-乙醛
2921211000-乙二胺 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-8349899-B1
优先权日:2008-12-03
标题:Selective inhibitors of EG5 motors and methods of use
发明人：ARTERBURN JEFFREY; SHUSTER CHARLES
权利人:ARROWHEAD CT INC; ARTERBURN JEFFREY; SHUSTER CHARLES
摘要:Embodiments of the present invention comprises a compound of formula I or its enantiomer, diastereomer, stereoisomer or its pharmaceutically acceptable salt, methods of use and methods of synthesis.
专利号:CN-101085809-B
优先权日:2006-06-06
标 题:Synthesis and preparation technology of batifiban and its analogues
专利号:CN-101993475-A
优先权日:2009-08-21
标 题 :Synthesis method of full liquid-phase Eptifibatide
专利号:US-2014315720-A1
优先权日:2012-10-24
标 题 :Polysaccharide ester microspheres and methods and articles relating thereto
发明人：FALLON DENIS G; GARRETT THOMAS S; KIZER LAWTON E; ZAZZARA KAREN L; COMBS MICHAEL T; JOHNSON RICHARD K; DEHART GARY
权利人:CELANESE ACETATE LLC
摘要:A method for producing a polysaccharide ester microsphere may include forming a polysaccharide ester product from a polysaccharide synthesis, wherein the polysaccharide ester product comprises a polysaccharide ester and a solvent; diluting the polysaccharide ester product, thereby yielding a polysaccharide ester dope; and forming a plurality of polysaccharide ester microspheres from the polysaccharide ester dope. Suitable polysaccharides may include, but are not limited to, starch, cellulose, hemicellulose, algenates, chitosan, and any combination thereof. Esters thereof may be organic esters (e.g., acetate and the like), inorganic esters (e.g., sulfonates and the like), or combinations thereof. Further, the solids conent of the polysaccharide ester dope, in some instances, may be greater than about 16 wt %.
专利号:CN-102924569-A
优先权日:2012-09-14
标 题 :Liquid phase synthesis method of eptifibatide
专利号:DE-69428401-T2
优先权日:1993-06-18
标 题 :Process for the preparation of alpha-amino acid amides for use in peptide synthesis
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品牌试剂参考报价(招募中)
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合成参考文献
参考文献:10.1016/j.bmcl.2007.04.101
摘要:Ogo N, Oishi S, Matsuno K, Sawada J, Fujii N, Asai A. Synthesis and biological evaluation of l-cysteine derivatives as mitotic kinesin Eg5 inhibitors. Bioorganic & Medicinal Chemistry Letters. 2007 Jul;17(14):3921–4. doi: 10.1016/j.bmcl.2007.04.101.
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