CAS: 13794-15-5; 2-(4-Methoxyphenoxy)Propanoic Acid

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94050-90-5 940-31-8 1129-46-0

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CAS号111479-08-4 ethyl 2-(4-meth... | CAS号17639-93-9 2-氯丙酸甲酯 | CAS号150-76-5 4-甲氧基苯酚(MEHQ) | CAS号598-72-1 2-溴丙酸 | CAS号598-78-7 2-氯丙酸 | CAS号535-11-5 2-溴丙酸乙酯 | CAS号935-50-2 4,4-DIMETHOXY-2... | CAS号150-76-5 4-甲氧基苯酚(MEHQ) | CAS号106-51-4 苯醌 | CAS号201230-82-2 carbon monoxide | CAS号75-07-0 乙醛 | CAS号1877-75-4 对甲氧基苯氧乙酸 | CAS号67648-61-7 2-(4-羟基苯氧基)丙酸 | CAS号17509-54-5 2-(4-甲氧基苯氧基)-2-甲基丙酸 | CAS号111479-08-4 ethyl 2-(4-meth... | CAS号69033-92-7 Propanoic acid,...

Lactisole置于磷酸体系中,用82%的收率获得2-(4-甲氧基苯氧基)丙酸
参考文献:非循环立体选择.23. 乳醛烯醇化物当量
标题:非循环立体选择.23. 乳醛烯醇化物当量
摘要:Etudie Lastereochimie De L'Addition D'Enolates D'Esters D'Acide O-Alkyllactique Aux Aldehydes
Doi:10.1021/ja00338A027

专利信息

专利号:US-6818633-B2
优先权日:2001-06-29
标题:Antiviral compounds and methods for synthesis and therapy
发明人：BALZARINI JAN M R; DE CLERCQ ERIK D A; HOLY ANTONIN
权利人:ACAD OF SCIENCE CZECH REPUBLIC; REGA STICHTING
摘要:Novel compounds are provided having formula (I)whereR1, R2, R3, R4, Z, X and * are defined herein. Also provided are antiviral methods for use and processes for synthesis of the compounds of formula (I).

专利号:US-7115592-B2
优先权日:2003-06-16
标题:Phosphonate substituted pyrimidine compounds and methods for therapy
发明人：BALZARINI JAN M R; DE CLERCQ ERIK D A; HOLY ANTONIN; HOCKOVA DANA
权利人:BIOCHEMISTRY OF THE ACADEMY OF
摘要:Novel compounds are provided having formula (I) n nwheren n R 1 , R 2 , R 3 , R 4 , Z, X and * are defined herein. Also provided are antiviral methods for use and processes for synthesis of the compounds of formula (I).

专利号:US-5585275-A
优先权日:1992-09-02
标 题 :Pilot apparatus for peptide synthesis and screening
发明人：HUDSON DEREK; JOHNSON CHARLES R; GIEBEL LUTZ
权利人:ARRIS PHARM CORP
摘要:Method and apparatus for simple and rapid preparation of reusable, addressable surface-immobilized arrays of biomolecules (libraries) used for screening for interaction with any biologically significant target. A special plate having on or in its surface a plurality of discreet functionalized substrate areas, typically in arrays of 10x10 to 400x400, is provided for chemical synthesis or bonding thereon of desired families of biomolecules (e.g. peptides, DNA, RNA, oligosaccharides). In the case of peptides, such as hexapeptides, the resulting permanently hexapeptide-loaded plate is a reusable Addressable Synthetic Peptide Combinatorial Library (ASPCL), in which 1 to 3 (typically two) of the positions in the sequence are uniquely identified by the address location. The preferred plate embodiment employs an HPMP wink of porous polyolefin removably received in holes in the plate. A unique multi-slot block assembly is used to prepare the ASPCLs. The wink carrier plate is also employed with a vacuum block system to assist in washing, deprotection, and probing. In library applications, for example determining peptides which bind to functional proteins (enzymes, receptors, antibodies), the substrate-bound peptides are assembled with several positions consisting of uniformly distributed equimolar mixtures of residues, and 2 separated or sequential positions uniquely identified by their spatial location on the substrate array, the 'address'. Following identification of the known residues giving the greatest affinity for the arrayed positions in the sequence, optimal binding for the complete peptide sequence is determined by an iterative process replacing formerly mixed positions with known AAs at unique addresses.

专利号:US-5886179-A
优先权日:1993-09-17
标 题 :Nucleotide analogs
发明人：ARIMILLI MURTY N; BISCHOFBERGER NORBERT W; JONES ROBERT J; LEE WILLIAM A; PRISBE ERNEST J
权利人:GILEAD SCIENCES INC
摘要:Nucleotide phosphonate esters characterized by the presence of an ester linked group which is bonded to the phosphorus atom of phosphonate nucleotide analogs are disclosed. The analogs comprise an ester bond that is hydrolyzed in vivo to yield a corresponding phosphonate nucleotide analog. Methods and intermediates for their synthesis and use are described.

专利号:CN-101735037-B
优先权日:2009-12-11
标 题:Synthesis method of sweet taste inhibitor 2-(4- methoxyphenyl) sodium propionate

专利号:US-5656745-A
优先权日:1993-09-17
标题:Nucleotide analogs
发明人：BISCHOFBERGER NORBERT; JONES ROBERT J; ARIMILLI MURTY; LIN KUEI-YING; LOUIE MICHAEL; MCGEE LAWRENCE R; PRISBE ERNEST J
权利人:GILEAD SCIENCES INC
摘要:Nucleotide analogs characterized by the presence of an amidate linked amino acid or an ester linked group which is bonded to the phosphorus atom of phosphonate nucleotide analogs are disclosed. The analogs comprise a phosphoamidate or ester bond that is hydrolyzed in vivo to yield a corresponding phosphonate nucleotide analog. Methods and intermediates for their synthesis and use are described.