CAS: 13425-84-8; Sulfuric Acid Monopropyl Ester

上下游产品

propan-1-ol diammonium salt of phenyl phosphatosulfate1-propyl-2-(2-hydroxyethyl)piperidine propyl 2-phenylquinoline-4-carboxylate 6-methyl-2-phenyl-quinoline-4-carboxylic acid propyl ester propan-1-ol

📜丙醇置于hydroxysteroid Sulfotransferase A,6-氨基-9-[3-羟基-5-[(羟基-磺基氧基-磷酰)氧基甲基]-4-膦酰氧基-四氢呋喃-2-基]-嘌呤,2-巯基乙醇体系中,用 Phosphate Buffer,丙酮 用作溶剂,化学反应 0.17H,反应生成硫酸氫丙酯
参考文献:底物结构对羟基甾类磺基转移酶sta在醇硫酸化中的催化效率的影响.
标题:底物结构对羟基甾类磺基转移酶sta在醇硫酸化中的催化效率的影响.
摘要:磺基转移酶a(sta)是羟基类固醇(醇)磺基转移酶的同工型,可催化内源性醇和异源性醇形成硫酸酯.在毒理学的各种功能中,Sta是大鼠肝磺基转移酶的主要形式,它催化由羟甲基多环芳烃形成遗传毒性和致癌性硫酸酯.本研究的目的是阐明底物结构与sta催化活性之间的基本定量关系,该关系适用于这些和其他异源生物.我们已经修改了先前纯化sta的程序,以便获得足够量的均相酶来测定kcat / Km值,这是催化效率的定量度量.我们确定了sta在苯甲醇和八种被对位正烷基(cnh2N +1,其中n = 1-8)取代的苯甲醇中的催化效率,以及在这些反应中kcat / Km的最佳值用正戊基苄醇制得.Kcat / Km值的对数与分配系数的对数之间的相关性表明,底物的疏水性是影响sta催化效率的主要因素.伯正烷醇(cnh(2N + 1)oh,其中n = 3-16)对c9-C11表现出最佳kcat / Km值,对c3-C14
Doi:10.1021/tx950065T

专利信息

专利号:US-9777022-B2
优先权日:2012-10-02
标题 :Process for the preparation of macrocyclic polyazacarboxylate ligands and chelates
发明人：MOORE DENNIS A; RAJAGOPALAN RAGHAVAN
权利人:MALLINCKRODT LLC; GUERBET SA
摘要:The present disclosure relates generally to a process for the synthesis of 1,4,7,10-tetraazacyclododecane ligands, chelates, and derivatives thereof. In particular, the present disclosure is directed to a process for the synthesis of 1,4,7,10-tetraaza-1,4,7,10-tetrakis(carboxymethyl)cyclododecane (DOTA) ligands, corresponding DOTA-metal chelates, and various derivatives thereof.

专利号:US-4532322-A
优先权日:1983-05-23
标题:Preparation of thiazine derivatives
发明人：JACKSON ARTHUR; HEYES GRAHAM
权利人:FINE ORGANICS LTD
摘要:A method for the preparation of a thiazine derivative of the formula ##STR1## where each R is independently selected from hydrogen or a lower alkyl having 1 to 4 carbon atoms, the method comprising reacting together a sulphur donor which is selected from sulfur, ammonium or alkali metal sulfides, ammonium or alkali metal hydrosulfides, or hydrogen sulfide, 1,1-bis(methylthio)-2-nitroethene and a compound of the formula n n H.sub.2 NCR.sub.2 CR.sub.2 CR.sub.2 OSO.sub.3 H n n where each R is as defined above. n A preferred method is for the preparation of tetra-2-(nitromethylene)-2H-1,3-thiazine which possesses broad spectrum insecticidal activity, and is also useful as an intermediate in the synthesis of other insecticides.

专利号:US-8288497-B2
优先权日:2008-02-27
标 题 :Synthesis of poly-(P-aryleneethynylene)s in neat water under aerobic conditions
发明人：KANG YOUN K; DERIA PRAVAS; THERIEN MICHAEL J
权利人:KANG YOUN K; DERIA PRAVAS; THERIEN MICHAEL J; UNIV PENNSYLVANIA
摘要:Provided are ethyne synthons comprising boron and related methods. Also provided are related water-soluble arylethynylene polymers capable of being synthesized in neat water under aerobic conditions.

专利号:WO-0001691-A1
优先权日:1998-07-01
标 题 :Process for making farnesyl-protein transferase inhibitors
发明人：ASKIN DAVID; COWEN JENNIFER A; MALIGRES PETER E; MCWILLIAMS J CHRISTOPHER; MCCAULEY JAMES A
权利人:MERCK & CO INC; ASKIN DAVID; COWEN JENNIFER A; MALIGRES PETER E; MCWILLIAMS J CHRISTOPHER; MCCAULEY JAMES A
摘要:The present invention is directed to the improved synthesis of compounds of formula (I): which may be useful as farnesyl-protein transferase inhibitors. The present invention is also directed to the crystal forms of the monohydrate and mon-hydrochloride salt of 1-(3-Chlorophenyl)-4-[1-(4-cyanobenzyl)-5-imidazolylmethyl]-2-piperazinone.

专利号:US-2009326150-A1
优先权日:2008-02-27
标题:Synthesis of poly-(p-aryleneethynylene)s in neat water under aerobic condit

专利号:US-4352788-A
优先权日:1979-08-09
标题 :Derivatives of 2,4,6-triiodo-isophthalic acid, processes for their synthesis and X-ray contrasting materials containing these
发明人：FELDER ERNST; PITRE DAVIDE
权利人:BRACCO IND CHIMICA SPA
摘要:Compounds for use in non-ionic X-ray contrasting materials having the formula ##STR1## in which (H0) 2-3 alkyl is 1,3-dihydroxyisopropyl, 2,3-dihydroxypropyl or 1,3-dihydroxy-2-hydroxymethylisopropyl, n R is hydrogen or methyl, and n R 1 is an alkyl residue with 1 to 5 carbon atoms. n These compounds possess high water-solubility as well as excellent stability against hydrolysis. Methods for preparation and use of the compounds are also disclosed.