CAS: 1201905-61-4; (E)-2-(2-Ethoxyvinyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane

相似化合物

219489-07-3 75927-49-0 167896-48-2

上下游产品

CAS号927-80-0 乙氧基乙炔,己烷溶液 | CAS号25015-63-8 频那醇硼烷 | CAS号109-92-2 乙烯基乙醚

📜乙氧基乙炔,频那醇硼烷置于schwartz'S Reagent体系中,用 正己烷,二氯甲烷 用作溶剂,化学反应 16.0H,以81%的收率获得(E)-1-乙氧乙烯基-2-硼酸频那醇酯
参考文献:新的桥接尼古丁类似物的简明合成
标题:新的桥接尼古丁类似物的简明合成
摘要:这项研究描述了一种非常有效的策略,用于合成两个新的桥接尼古丁类似物.从4-或3-氯吡啶开始,仅需三步即可得到所需的三环系统,总产率分别为23%和40%.
Doi:10.1016/j.Tet.2011.12.029

专利信息

专利号:US-2024309003-A1
优先权日:2021-05-04
标题 :Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use
发明人：HOUZE JONATHAN B; BOS MAXENCE; MANCUSO JOHN; FRANZONI IVAN; PANDYA BHAUMIK; KAPLAN ALAN
权利人:VIGIL NEUROSCIENCE INC
摘要:The present disclosure provides compounds of Formula I, useful for the activation of Triggering Receptor Expressed on Myeloid Cells 2 (“TREM2â€?). This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a neurodegenerative disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.

专利号:US-9243002-B2
优先权日:2013-02-07
标题 :Tetracyclic heterocycle compounds and methods of use thereof for the treatment of hepatitis C
发明人：DAI XING; LIU HONG; PALANI ANANDAN; HE SHUWEN; BROCKUNIER LINDA L; NARGUND RAVI; MARCANTONIO KAREN; ZORN NICOLAS; XIAO DONG; PENG XUANJIA; LI PENG; GUO TAO
权利人:MERCK SHARP & DOHME
摘要:The present invention relates to compounds of formula I that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

专利号:WO-2023086799-A1
优先权日:2021-11-09
标 题:Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists
发明人：HOUZE JONATHAN B; PANDYA BHAUMIK; KAPLAN ALAN P
权利人:VIGIL NEUROSCIENCE INC
摘要:The present disclosure provides compounds of Formula I, useful for the activation of Triggering Receptor Expressed on Myeloid Cells 2 ('TREM2'). This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a neurodegenerative disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.

专利号:US-2023119463-A1
优先权日:2019-12-27
标题 :1h-pyrrolo[2,3-b]pyridine derivatives as bcl-2 inhibitors for the treatment of neoplastic and autoimmune diseases
发明人：CHEN YI
权利人:NEWAVE PHARMACEUTICAL INC
摘要:The present invention relates to 1H-pyrrolo[2,3-b]pyridine derivatives and related compounds as BCL-2 inhibitors for treating neoplastic, autoimmune or neurodegenerative diseases. The present description discloses the synthesis and characterisation of exemplary compounds as well as pharmacological data thereof (e.g. pages 162 to 233; examples 1 to 8; table; compound examples cpd-1 to cpd-135; biological examples 1 to 4).

专利号:WO-2022133332-A2
优先权日:2020-12-17
标题 :Synthesis of cannabidiol and analogs thereof, and related compounds, formulations, and methods of use

专利号:US-2023357177-A1
优先权日:2020-12-17
标题:Synthesis of cannabidiol and analogs thereof, and related compounds, formulations, and methods of use