专利号:US-7842813-B2 优先权日:2008-05-09 标 题 :Processes for the preparation of O-[5-(4-amino-thiazol-2-yl)-pyridin-2-ylmethyl]-hydroxylamine 发明人:TANG DATONG; HAN YINGLIN; HUANG YANHE; PHAN LY TAM; OR YAT SUN; WANG ZHE 权利人:ENANTA PHARM INC 摘要:The present invention relates generally to novel methods for the synthesis of O-[5-(4-amino-thiazol-2-yl)-pyridin-2-ylmethyl]-hydroxylamine which is an essential reagent in the synthesis of one of the bridged erythromycin derivatives and their respective pharmaceutically acceptable salts in PCT Application WO 03/097659 A1. In particular, the present invention relates to processes and intermediates for the preparation of a compound of formula (Ia):
专利号:US-6914144-B2 优先权日:2002-01-29 标 题:Process for preparing integrin antagonist intermediate 发明人:PYE PHILIP J 权利人:MERCK & CO INC 摘要:A process is provided for the preparation of 2,5-di-(3′-aminopropyl)pyridine which is useful in the synthesis of αvβ3 integrin receptor antagonists. Also provided are useful intermediates obtained from the process.
专利号:RU-2090565-C1 优先权日:1991-02-27 标题 :Racemic or optically active perhydro-1h-pyrido-[1,2-a]-pyrazines or their pharmaceutically acceptable salts and method of their synthesis
[参考文献]: Marta Soler, Et Al. Design, Preparation, And Characterization Of Zn And Cu Metallopeptides Based On Tetradentate Aminopyridine Ligands Showing Enhanced Dna Cleavage Activity. Inorg Chem. 2015 Nov 16;54(22):10542-58.
合成参考文献
参考文献:10.1134/s1070328425600561 摘要:Smirnov DE, Bezzubov SI. Synthesis, Structure, and Optical and Electrochemical Properties of a Chromophoric Cyclometalated Iridium(III) Complex. Russ J Coord Chem. 2025 Jun;51(6):514–21. doi: 10.1134/s1070328425600561.