CAS: 79636-94-5; 5-Bromo-2-Ethoxybenzaldehyde

该化合物是一种有机化合物,以其芳香结构为特征,以溴原子为特征,并有一个与苯并二甲胺协会附属的乙氧基组为特征,其分子配方反映溴原子的存在,一个乙氧基组(OO CH2欧元3)和一个甲醛功能组(Eurosho)的存在,该化合物一般是无色的黄色液体或固体,视其纯度和温度而定.该化合物以其再活动性为特征,特别是其因溴苯并二甲胺原子的电子脱氧性而导致的电光化替代反应,这可能影响在芳香环上进一步替代的取向.此外,甲氨基苯并功能组使其易受氧化和凝聚反应的影响. 5-Bromo-2-乙氧基苯甲醚在各种合成应用中使用,包括制药,农用化学剂和其他精密化学品.在处理该化合物时,应当遵守安全防范措施,因为如果在处理该化合物时可能构成健康风险.

结构式图片

上下游产品

CAS号75-03-6 碘乙烷 | CAS号1761-61-1 5-溴水杨醛 | CAS号74-96-4 溴乙烷 | CAS号79636-93-4 4-溴-1-乙氧基-2-甲基苯 | CAS号149489-18-9 5-BROMO-2-ETHOX... | CAS号613-69-4 2-乙氧基苯甲醛

合成工艺路线路线简述

  • 79636-93-4 = 79636-94-5
    反应条件:1.1 Reagents: Copper Sulfate
    标题:Facile Conversion Of Electron Rich Benzylic Hydrocarbons To Carbonyl Compounds By Peroxydisulfate And Copper Ions
    作者:Bhatt,M. Vivekananda; Perumal,P. Thirumalai
    参考文献:Tetrahedron Letters 日期:1981 卷标:22(27) 页码:2605-8]

    1761-61-1 = 79636-94-5
    反应条件:1.1 Reagents: Potassium Carbonate Solvents: Dimethylformamide; Overnight,Rt
    标题:Structural Simplification Of A Tetrahydroquinoline-Core Peptidomimetic μ-Opioid Receptor (Mor) Agonist/δ-Opioid Receptor (Dor) Antagonist Produces Improved Metabolic Stability
    作者:Henry,Sean P.; Fernandez,Thomas J.; Anand,Jessica P.; Griggs,Nicholas W.; Traynor,John R.; Et Al
    参考文献:Journal Of Medicinal Chemistry 日期:2019 卷标:62(8) 页码:4142-4157]

    1761-61-1 = 79636-94-5
    反应条件:1.1 Reagents: Potassium Carbonate Solvents: Dimethylformamide; 2 D,Rt
    标题:Synthesis And Bioevaluation Of Substituted Chalcones,Coumaranones And Other Flavonoids As Anti-Hiv Agents
    作者:Cole,Amy L.; Hossain,Sandra; Cole,Alex M.; Phanstiel,Otto Iv
    参考文献:Bioorganic & Medicinal Chemistry 日期:2016 卷标:24(12) 页码:2768-2776]

    1761-61-1 = 79636-94-5
    反应条件:1.1 Reagents: Potassium Carbonate Solvents: Dimethylformamide; 2 D,Rt
    标题:Development Of Flavonoid-Based Inverse Agonists Of The Key Signaling Receptor Us28 Of Human Cytomegalovirus
    作者:Kralj,Ana; Nguyen,Mai-Thao; Tschammer,Nuska; Ocampo,Nicolette; Gesiotto,Quinto; Et Al
    参考文献:Journal Of Medicinal Chemistry 日期:2013 卷标:56(12) 页码:5019-5032
📜2-乙氧基苯甲醛置于溴体系中,化学反应生成 5-溴-2-乙氧基苯甲醛
参考文献:Perkin,Justus Liebigs Annalen Der Chemie,1868,Vol. 145,P. 302
标题:Perkin,Justus Liebigs Annalen Der Chemie,1868,Vol. 145,P. 302

海关参考信息

专利信息


专利号:US-2021284618-A1
优先权日:2016-08-12
标 题 :Furanochalcones as inhibitors of cyp1a1, cyp1a2 and cyp1b1 for cancer chemoprevention
发明人:BHARATE SANDIP BIBISHAN; SHARMA RAJNI; JOSHI PRASHANT; VISHWAKARMA RAM; CHAUDHURI BHABATOSH
权利人:COUNCIL SCIENT IND RES; DE MONTFORT UNIV
摘要:The present invention relates to the furanochalcone class of compounds of general formula A. The present invention particularly relates to the synthesis of furanochalcones and their CYP1A1, CYP1A2 and CYP1B1 inhibitory activity. In addition, the invention relates to the prevention or treatment of cancer caused by polyaromatic hydrocarbons (PAHs), 4-nitroquinoline-1-oxide, and N-nitroso-N-methylurea, heterocyclic amines, estrogen and 17β-estradiol, resulting from the inhibition of CYP1A1, CYP1A2 and CYP1B1 enzymes.

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

主要参考文献

参考标题:Synthesis Of Aromatic Carboxylic Acids By Carbonylation Of Aryl Halides In The Presence Of Epoxide-Modified Cobalt Carbonyls As Catalysts
作者:V. P. Boyarskii,T. E. Zhesko,S. A. Lanina |发布日期:2005.11
摘要:A New Procedure Was Developed For Synthesis Of Aromatic And Heteroaromatic Acids And Their Derivatives (Esters, Salts) By Carbonylation Of The Corresponding Aryl Halides. The Acids Are Selectively Formed In A High Yield Under Very Mild Conditions. Highly Active Catalytic Systems, Base-Containing Alcoholic Solutions Of Cobalt Carbonyl Modified With Epoxides, Were Used To Activate Aryl Halides.

合成参考文献


参考文献:10.1104/pp.17.00433
摘要:Wase N, Tu B, Allen JW, Black PN, DiRusso CC. Identification and Metabolite Profiling of Chemical Activators of Lipid Accumulation in Green Algae. Plant Physiol. 2017 Aug;174(4):2146–65.
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