CAS: 6860-47-5; (2R,3R,4R)-2,3,5-Trihydroxy-4-(((2S,3R,4S,5R)-3,4,5-Trihydroxytetrahydro-2H-Pyran-2-yl)Oxy)Pentanal

上下游产品

β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-D-Xyl β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-β-D-Xylp-(1-4)-β-D-Xyl xylopentaose xylohexaoseD-xylose

Xylohexaose置于polyethylenimine-Coated Selenomonas Ruminantium β-Xylosidase Immobilized On Glyoxyl Agarose,水体系中,用 Aq. Acetate Buffer 作为反应溶剂,化学反应 4.0H,反应生成 木二糖
参考文献:β-Xylosidase From Selenomonas Ruminantium: Immobilization,Stabilization,And Application For Xylooligosaccharide Hydrolysis
标题:β-Xylosidase From Selenomonas Ruminantium: Immobilization,Stabilization,And Application For Xylooligosaccharide Hydrolysis
摘要:The Tetrameric-Xylosidase From Selenomonas Ruminantium Is Very Stable In Alkaline Ph Allowing It To Easily Immobilize By Multipoint Covalent Attachments On Highly Activated Glyoxyl Agarose Gels. Initial Immobilization Resulted Only In Slight Stabilization In Relation To The Free Enzyme,Since Involvement Of All Subunits Was Not Achieved. Coating The Catalyst With Aldehyde-Dextran Or Polyethylenimine,Fully Stabilized The Quaternary Structure Of The Enzyme Rendering Much More Stabilization To The Biocatalyst. The Catalyst Coated With Polyethylenimine Of Molecular Weight 1300 Is The Most Stable One Exhibiting An Interesting Half-Life Of More Than 10 Days At Ph 5.0 And 50 Degrees C,Being,Therefore,240-Fold More Stable Than Free Enzyme. Optimum Activity Was Observed In The Ph Range 4.0-6.0 And At 55 Degrees C. The Catalyst Retained Its Side Activity Against P-Nitrophenyl-L-Arabinofuranoside And It Was Inhibited By Xylose And Glucose. Kinetic Parameters With P-Nitrophenyl-D-Xylopyranoside As Substrate Were V-Max 0.20Mol.Min(-1)Mgprot.(-1),K-M 0.45Mm,K-Cat 0.82S(-1),And K-Cat/k-M 1.82S(-1)Mm(-1). Xylose Release Was Observed From The Hydrolysis Of Xylooligosaccharides With A Decrease In The Rate Of Xylose Release By Increasing Substrate Chain-Length. Due To The High Thermostability And The Complete Stability After Five Reuse Cycles,The Applicability Of This Biocatalyst In Biotechnological Processes,Such As For The Degradation Of Lignocellulosic Biomass,Is Highly Increased.
DOI:10.1080/10242422.2016.1247817

专利信息

专利号:US-7344863-B2
优先权日:1998-03-13
标题:Methods for producing polypeptides through enhanced synthesis of encoding nucleic acid molecules
发明人：LI WU-BO; JESSEE JOEL A; SCHUSTER DAVID; XIA JIULIN; GEBEYEHU GULILAT
权利人:INVITROGEN CORP
摘要:The present invention is directed to compositions and methods for enhancing synthesis of nucleic acid molecules, particularly GC-rich nucleic acid molecules. Specifically, the invention provides compositions comprising one or more nitrogen-containing organic compounds having a formula selected from the group consisting of formula I and formula II (or salts or derivatives thereof), preferably 4-methylmorpholine N-oxide or betaine (carboxymethyltrimethylammonium), and further comprising one or more compounds selected from the group consisting of proline and an N-alkylimidazole compound, and more preferably proline, 1-methylimidazole or 4-methylimidazole. The invention further relates to methods for enhanced, high-fidelity synthesis of nucleic acid molecules, including via amplification (particularly PCR), reverse transcription, and sequencing methods. The invention also relates to nucleic acid molecules synthesized by these methods, to fragments or derivatives thereof, and to vectors and host cells comprising such nucleic acid molecules, fragments, or derivatives. The invention also relates to kits for synthesizing, amplifying, reverse transcribing or sequencing nucleic acid molecules comprising one or more of the compositions of the invention.

专利号:US-10973847-B2
优先权日:2017-06-30
标题 :Core-to-surface polymerization for the synthesis of star polymers and uses thereof
发明人：JOHNSON JEREMIAH A; GOLDER MATTHEW R
权利人:MASSACHUSETTS INST TECHNOLOGY
摘要:Disclosed are methods, compositions, reagents, systems, and kits to prepare star polymers, as well as compositions and uses thereof. Various embodiments show that synthesis of these polymers contain low metal concentration to provide polymers for diverse biomedical applications including in vivo applications.

专利号:US-7732414-B2
优先权日:2000-12-22
标题 :C-glycoside compounds for stimulating the synthesis of glycosaminoglycans
发明人：DALKO MARIA; BRETON LIONEL
权利人:OREAL
摘要:C-glycoside compounds are suited for stimulating the synthesis of glycosaminoglycans containing a D-glucosamine and/or N-acetyl-D-glucosamine residue, advantageously hyaluronic acid, and/or proteoglycans, advantageously proteoglycans containing hyaluronic acid, by fibroblasts and/or keratinocytes.

专利号:US-9447149-B2
优先权日:2012-03-06
标 题 :Methods and compositions for the rapid synthesis of radiometal-labeled probes
发明人：CHEN KAI; CONTI PETER STEPHEN
权利人:UNIV SOUTHERN CALIFORNIA
摘要:The present application is directed to rapid and efficient synthesis of radiometal-labeled probes, pharmaceutical compositions comprising radiometal-labeled probes, and methods of using the radiometal-labeled probes. Such radiometal-labeled probes can be used in imaging studies, such as Positron Emitting Tomography (PET) or Single Photon Emission Computed Tomography (SPECT), and therapy studies.

专利号:US-11390890-B2
优先权日:2015-02-15
标 题:Dibasic organic acid producing strain and preparation and application of same
发明人：TIAN CHAOGUANG; LI JINGEN; LONG CHUANNAN; SUN TAO; LIN LIANGCAI; XU JING; LIU QIAN; JI JINGXIAO; SUN WENLIANG; MA YANHE
权利人:TIANJIN INST IND BIOTECHNOLOGY CAS
摘要:Provided are an engineered strain for synthesizing a dibasic organic acid and preparation and application of same. The engineered strain introduces or up-regulates expression of a positive regulator gene for synthesis of a dibasic organic acid, and/or down-regulates expression of a negative regulator gene for synthesis of a dibasic organic acid, as compared with the origin strain of the engineered strain, the producing capability for producing the dibasic organic acid is improved. The dibasic organic acid comprises malic acid, succinic acid, fumaric acid, oxaloacetic acid, glutaric acid, and adipic acid; the expression product of the positive regulator gene comprises aspartate aminotransferase, glutamic acid-aspartate transporter, C4-dicarboxylic acid transporter, pyruvate carboxylase and malate dehydrogenase, glucose transporter; the expression product of the negative regulatory gene comprises succinyl-CoA synthase, and malic acid-alpha ketoglutarate transporter, and the original strain comprises Myceliophthora thermophila, Thielavia terrestris, Aspergillus , and Rhizopus.

专利号:US-6531454-B1
优先权日:1999-03-16
标 题:Glycosylated polyamines and methods of use therefor
发明人：LEARY JULIE A; GAUCHER SARA P; PEDERSEN STEVEN F
权利人:UNIV CALIFORNIA
摘要:Glycosylated polyamines comprising of mono- or oligo-saccharides that are glycosidically linked to an aliphatic polyamine, and pharmaceutically acceptable salts, prodrugs and derivatives thereof are provided. An exemplary glycosylated polyamine has the following structure: n Glycosylated polyamines, their pharmaceutically acceptable salts, prodrugs and derivatives are useful, for example, as anticancer compounds for the treatment of a variety of cancers. Methods for synthesis of glycosylated polyamines are disclosed. In addition, metal complexes of glycosylated polyamines, the preparation of such metal complexes, analytical methods using the metal complexes are provided. Methods for detecting equatorial and axial conformation of a group other than hydrogen at the C2 position of a saccharide molecule are also provided. The compounds of the invention can be used as anti-cancer agents (e.g., against breast, ovarian, colon or renal cancers). Furthermore, the compounds of the invention are ligands for the estrogen receptor and thus can be used to modulate estrogen receptor activity, for example to treat or prevent breast cancer, to treat or prevent osteoporosis or to reduce the risk of cardiovascular disease in a subject (e.g., a postmenopausal female subject).