CAS: 548-51-6; 2-Hydroxy-3-Isopropyl-6-Methylbenzoic Acid

该化合物是一种属于苯化酸类别的有机化合物,具有一种含有羟基,异丙基的苯化酸核心,以及芳香环上特定位置的甲基替代成分.该化合物一般是白色至白色晶状固体,其特点是有机溶剂中具有中等溶性,水溶解性有限.应参考安全数据,以便处理和接触任何化学物质的准则.

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CAS号89-83-8 麝香草酚 | CAS号124-38-9 二氧化碳 | CAS号112404-71-4 (2-isopropyl-5-... | CAS号56-23-5 四氯化碳 | CAS号463-79-6 碳酸钇二水 | CAS号112404-79-2 thymol 2-tetrah... | CAS号50397-25-6 N-Silber-N-chlo... | CAS号7664-93-9 硫酸 | CAS号108-88-3 甲苯 | CAS号112404-43-0 6-methyl-2-phen... | CAS号4399-52-4 邻麝香草酸的环三内酯 | CAS号50397-25-6 N-Silber-N-chlo...

合成工艺路线路线简述

    📜百里酚置于盐酸体系中,用 乙酸乙酯 作为反应溶剂,化学反应生成 2-羟基-3-异丙基-6-甲基苯甲酸
    参考文献:Substituent Modification In Tri-O-Thymotide And Its Effects On Host Geometry And Guest Enclathration .1. Synthesis
    标题:Substituent Modification In Tri-O-Thymotide And Its Effects On Host Geometry And Guest Enclathration .1. Synthesis
    摘要:
    DOI:10.1016/s0040-4020(01)90268-6

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    专利信息


    专利号:US-9453037-B2
    优先权日:2011-07-28
    标 题 :Methylphenidate-prodrugs, processes of making and using the same
    发明人:GUENTHER SVEN; CHI GUOCHEN; BERA BINDU; MICKLE TRAVIS; BERA SANJIB
    权利人:KEMPHARM INC; KEMPHARM INC
    摘要:The present technology is directed to prodrugs and compositions for the treatment of various diseases and/or disorders comprising methylphenidate, or methylphenidate derivatives, conjugated to at least one alcohol, amine, oxoacid, thiol, or derivatives thereof. In some embodiments, the conjugates further include at least one linker. The present technology also relates to the synthesis of methylphenidate, or methylphenidate derivatives, conjugated to at least one alcohol, amine, oxoacid, thiol, or derivatives thereof or combinations thereof.

    专利号:US-9217012-B2
    优先权日:2009-04-08
    标题 :Inhibitors of protein tyrosine phosphatases
    发明人:ZHANG ZHONG-YIN; ZHANG SHENG
    权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP
    摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.

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    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: F J Marozzi, Et Al. Analgesic And Anti-Inflammatory Evaluation Of Thymotic Acid And Certain Homologs. J Pharm Sci. 1968 Jun;57(6):989-94.

    合成参考文献


    摘要:Farmaco, Edizione Scientifica., 20(506), 1965 []
    摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198
    参考文献:10.1002/jps.3030430710
    摘要:Granatek E, Jannke P. Dehydration Products of o-Thymotic Acid*. Journal of the American Pharmaceutical Association (Scientific ed.). 1954 Jul;43(7):421–2. doi: 10.1002/jps.3030430710.
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